Objective:To Explore the correlation between silent cerebral infarcti on(SCI) and aged depression.Methods:SCI was analyzed in 90 aged patients w ith or without depression. Results:Incidence rate of SCI was 71.1% in 45 aged p ersons with depression(depression group), but incidence rate of SCI was 13.56% i n 45 aged persons without depression(no depression group). Compared no depressio n group the SCI incidence rate of depression group was obviously increase(P< 0.01).Conclusion: There is significantly correlation between SCI and aged depression