Objective To evaluate the therapeutic efficacy and safety of Wenxin Particle combined with amiodarone in the treatment of premature ventricular beats.Methods 78 cases with premature ventricular beats were divided into observation group(n=40)and control group(n=38).The observation group was treated with Wenxin Particle and amiodarone,the control group was treated amiodarone with only.The improvement of clinical symptoms and premature ventricular beats and the side effects were observed.Results Total effective rate was 78.94％ in control group,92.50％ in observation group.There was a significantly statistical difference between two groups(P＜0.05).Conclusion Wenxin Particle combined with amiodarone in treating premature ventricular beats can improve the clinical effect and have no obvious side effect,so it is worth being used widely.

Objective: To establish normative value of multiple segments motor nerve conduction of bilateral median nerve and ulnar nerve, including motor nerve conduction velocity (MCV)、latency (LAT)and amplitude (AMP). Method: Two hundred normal volunteers were divided into 5 groups according to different ages. Median nerve was examined at multiple points: palm, wrist, elbow, axilla and Erb's. Ulnar nerve was examined at multiple points: wrist, below elbow, above elbow, axilla and Erb's. The values of segmental MCV, LAT and AMP were recorded. Result: Gender and sidedness had no effect on MCV, LAT and AMP of median nerve and ulnar nerve. However, age had significant effects on MCV, LAT and AMP of median nerve and AMP of ulnar nerve. Conclusion: The examination of multiple segments motor nerve conduction of bilateral median nerve and ulnar nerve possess important value in diagnosis.

Objective:To retrospectively evaluate whole body ~(18)F-FDG PET/CT in depicting the primary tomors in cervical metastatic adenocarcinoma of unknown primary site.Methods:Seventeen patients were included and underwent whole body PET/CT imaging.The primary tumors and metastases were detected by visual evaluation and measurements of standardized uptake values.The PET/CT impression was verified by histopathology and(or)follow-up.Results:In 17 patienis,primary tumors of 13 patients were confirmed by pathological or clinical follow-up.Among them,8 were in the lung,1 in breast,1 in renal,2 in colon and 1 in cervix.Among the other 4 cases,3 cases were correctly diagnosed as malignant lymphoma finally by PET/CT instead of metastatic adenoearcinoma previously.The sensitivity,specificity and accuracy of PET/CT in were 92.3%,75.0% and 88.2%,identifying primary tumors respectively.After PET/CT examination,10 patients(58.8%)were detected additional metastatic lesions which were missed previously.Conclusion:Whole body ~(18)F-FDG PET/CT may be of relatively higher value in identifying the primary tumor of cervical metastatic adenocarcinoma from unknown primary site.It also may display tumor involvement extent.

Objective To investigate the correlation between serum procalcitonin (PCT) and acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ) score and prognosis in acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Methods A total of 88 patients with AECOPD admitted to emergency department of Peking university third hospital were prospectively studied,and were divided into three groups,namely high score group,median score group and low score group according to APACHE Ⅱ score.Serum PCT,hypersensitive C-reactive protein (hs-CRP),WBC and lactate were assayed within the first 24 hours after admission,the differences in those indicators between three groups were analyzed; and the correlation between PCT and APACHE Ⅱscore,hs-CRP,WBC,lactate were investigated.The patients were divided into survival group and death group according to prognosis,and the differences in those indicators between the two groups were analyzed.Results The serum levels of PCT was higher in high score group (0.60±0.32) ng/ml than that in median score group (0.36 ±0.23) ng/ml and that in low score group (0.24 ±0.19) ng/ml,differences between groups were statistically significant (P ＜0.01).The hs-CRP was higher in high score group M (P25,P75) 36.88 (10.14,47.16) mg/L than that in median score group 15.00 (3.64,30.33) mg/L and that in low score group 14.77 (4.35,15.80) mg/L (P =0.046).The PCT significantly correlated with APACHE Ⅱ and hs-CRP (P ＜0.01).The serum levels of PCT,APACHE Ⅱ score,hs-CRP and lactate were significantly higher in death group than those in survival group (P ＜ 0.05).Conclusions There is a good correlation between PCT and APACHE Ⅱ score in patients of AECOPD,suggesting PCT to be a sensitive predictor of prognosis.

Objective :To establish a RP-HPLC method for determination of isofraxidin in Pientzehuang oral tablet. Methods: RP-HPLC analysis was carried out on Nava-Pak C18 column and with acetonitrile: 0.1%phosphoric acid (15∶85) as a mobile phase. Results: The linear range was 12.9～90.3 ?g/mL(r=0.9999,n=7).The average recovery rate was 102.65 %and RSD=0.71 %.The intra-day and inter-day RSD was less than 3 %.Conclusion :This method is simple, rapid and accurate and suitable for the quality control of the preparations of Chinese herbal medicine containing isofraxidin.

Objective To evaluate the early diagnostic value of human heart-type fatty acid- binding protein (H-FABP) of acute coronary syndrome (ACS) and compare the diagnostic accuracy of different combination regimens of cardiac markers. Methods A total of 103 consecutive patients with chest pain (within 6 h after admission to Peking University Third Hospital,emergency department) suggestive of ACS were recruited for the analysis from April,2010 to June,2011.The blood levels of H-FABP,cardiac troponin-T (cTnT) and creatine kinase-myocardial band (CK-MB) were obtained at admission. The sensitivity,specificity,positive predictive value and negative predictive value together with the sensitivity and specificity in different phases of illness at admission were analyzed and compared among H-FABP,cTnT,CK-MB and different combinations by using SPSS version 17.0 software.Results Within 6 h of onset of symptom,the overall sensitivities of H-FABP,cTnT and CK-MB were 62.5％,30.6％ and 33.3％ respectively for patients with ACS.The sensitivity of H-FABP was significantly higher than that of cTnT and CK-MB (P ＜0.01 ).There were no differences in specificity and positive predictive value.The combination of H-FABP with cTnT had the greatest negative predictive value (53.8％ ).The sensitivity of H-FABP was higher during 3 - 6 h (77.8％ ) than during 0 - 3 h (53.3 ％ ) after chest pain onset (P =0.038).Within 0 - 3 h of onset of AMI,the overall sensitivities of the combination of H-FABP with cTnT and H-FABP with CK-MB (55.6％) were significantly higher than the combinaton of cTnT with CK-MB ( 24.4％ ) ( P =0.003 ).The sensitivity of the combination of H-FABP with cTnT was higher than that of single H-FABP during 0- 3 h and 3 -6 h after onset of AMI with increment in 3.3％ and 7.4％ respectively.The combination of H-FABP with cTnT had the greatest sensitivity ( 85.2％ ) during 3 - 6 h after onset.Conclusions H-FABP is the most sensitive cardiac marker in diagnosing of ACS in the early phase within 6 h,especially during 3 -6 h after onset.The sensitivity of the combination of H-FABP with cTnT is higher than that of H-FABP alone.The combination of H-FABP with cTnT has the best diagnostic value during 3 -6 h after onset of ACS.

Objective:To design a tuberculosis(TB) laboratory equipment management system based on Internet of Things (IOT), and put forward the specific plan of IOT technology used in TB laboratory equipment management.Methods: Bases on data acquisition technology, wireless mobile terminal based on wireless LAN technology, radio frequency identification (RFID) technology and computer technology, the Web application system architecture built equipment management system to realize internal information sharing and management of laboratory equipment.Results: The tuberculosis laboratory equipment management system using RFID networking technology and 2-dimensional bar code identification based on recognition, positioning and tracking of equipment, built system architecture by the user login module, device management module, equipment ledger management module and public affairs workflow management module. It has high efficiency, and is convenient for data query, updating and unifying management, information monitoring, real-time dynamic effect of maintenance equipment for positioning and bio safety management.Conclusion:The application of program links TB laboratory equipment management system networking and related technology based on IOT can achieve recognition, positioning and tracking of laboratory equipment, and also can effectively improve the overall level of laboratory equipment management intelligence and laboratory management efficiency.

Objective Effect of preventing recurrent pterygium excision combining amnion transplant by using recombinate interferon aIb drip eyes. Methods 105 cases of pterygium excision and combining amnion transplant patients were divided two groups,one group was treated by interferon aIb dripping eyes for 50 pterygium, another group was treated by 0.1%fu mi long drip eyes liquid to drop eyes as a contrast group. Results 50 patients in treatment group were followed up a case by regular visits to months after the operation and none of them had not been seen pterygium recurrent after passing 12～24 months and average time was 15 months;55 patients in contrast group had 6 recurrents,recurring rate was 10.9%,the statistic difference was significant( P

Objective·To compare the stress distribution at abutments, edentulous ridge, and peri-implant tissue under the vertical load between the RPI-type removable partial denture supported by implants with different diameter and the conventional RPI-type removable partial denture using a three-dimensional photoelastic method. Methods·The mandibular Kennedy I type denture defect models were fabricated according to the standard mandibular model. Four Straumann system soft tissue level implants with different diameters (two 4.1 mm implants and two 3.3 mm implants) were implanted into the bilateral first molar areas. Planting nails and epoxy resin teeth were inversely put into the mandibular silicone rubber molds to fabricate the epoxy resin photoelastic models and the regular neck (RN) healing abutments were screwed into the implants. A simulated alveolar mucosa with thickness of 2mm and a conventional RPI-type removable partial denture were placed on the epoxy resin models with or without implants. Then a force of 1 kg was vertically applied by a bite force loading device which fixed the model and denture in the centric occlusion. After the stress was frozen, model slices at different areas were cut and the stress fringes were observed. The stress was calculated according to the fringe value of per unit thickness. Results·For the conventional RPI-type removable partial denture, the maximum stress of distal abutment was mainly concentrated on the apical regions and the maximum stress of edentulous ridge was concentrated on the first molar area, particular on the lingual side of alveolar bone. For the implant-supported RPI-type removable partial denture, the maximum stress of distal abutment was lower than that of the conventional RPI-type removable partial denture, and the maximum stress of edentulous ridge (without the implants) was similar to that of abutment and supporting tissues and was lower than that of the conventional RPI-type removable partial denture. The stress around the implant was the largest and the peri-apical stress of implant was greater than the neck stress of implant. Meanwhile, the maximum stress around the implant was increased with the decrease of implant diameter. Conclusion·Compared to the conventional RPI-type removable partial denture, removable partial dentures supported by implants are more stable with a more balanced stress distribution in supporting tissues, thus benefit the health of abutments and supporting tissues.

ObjectiveTo review the surgical technique and outcome of intracranial angiographically occult vascular malformations (AOVM) hemorrhage. Methods40 patients with spontaneous intracranial hemorrhage episodes and accepted microsurgery were analyzed retrospectively. ResultsAll AOVMs were successfully resected. No operative death occurred.36 patients were followed up for mean 28 months. CT and/or MRI revealed no residual lesions. Most neurological complications improved postoperatively. 1 case demonstrated rebleeding in surgical site 48 months after operation. Another case, a follow-up MRI scan revealed a contralateral denovo lesion 44 months after operation.ConclusionA current neurosurgical procedure is a satisfactory method to prevents AOVMs rebleeding. Long-term follow-up evaluation is necessary despite the lesion has been totally resected.