In recent years,the research of Kangai injection,which is one of TCM anti-tumor injections,has been recognized as the most active areas of tumor treatment.To lung cancer patients,solo Kangai injection therapy could improve their quaility of life.It can also increase the efficiency,enhance the immune function,decrease the incidence of toxicities and adverse reactions when it has been combined with chemotherapy or radiotherapy.Overall,Kangai injection is effective in improving therapeutic effect and reducing side-effects of chemotherapy or radiotherapy.This article will discuss about recent research status of Kangai injection in the treatment of lung cancer.

Objective To confirm the risk factors of poor prognosis in patients with severe acute epiglottitis by comparing symptoms and results of laboratory tests.Methods A total of 698 patients with acute epiglottitis from outpatient and emergency room from 1995 to 2014 were retrospectively studied.These patients were divided into severe or mild group as per the means of treatment of airway including invasive (n =115)and non-invasive (n =583).The past history,general conditions and laboratory tests were compared between the two groups by chi-square or t test;the spearman correlation between the degree of dyspnea and epiglottis edema was analyzed,and the risk factors of poor prognosis were detected by logistic regression.Results The ratio of male to female was 1.366/1.There was a high prevalence of sever acute epiglottitis in spring,winter and at night, respectively.More smokers were found in the severe group compared with the mild group (χ2 =41.957,P <0.01).Severe dyspnea and low PaO2 (r =0.573,P <0.01),but not the poor grading of epiglottis edema evaluated by pharyngo-fiberoscope (r =-0.024,P =0.525),were correlated with poor prognosis.Male (OR =1.84,95%CI:1.41 -3.22,P =0.001),an attack at night (OR =2.61,95%CI:1.98 -3.16),P =0.07), smoker (OR =1.63,95%CI:1.05 -3.39,P =0.04)and low PaO2 (OR =2.97,95%CI:1.58 -4.49,P =0.02)were independent risk factors for a poor prognosis.Conclusions Male,an attack at night,smoker and low PaO2 were independent risk factors for a poor prognosis of acute epiglottitis.A critical care should be given to patients with those risk factors,even their epiglottis edema was not very serious.

Audiometry, Pure-Tone ; Hearing Loss, Sensorineural ; Humans ; Speech Perception

Objective To investigate the clinical efficacy of surgery treatment of benign prostatic hyperplasia in elderly patients.Methods 60 elderly patients with prostatic hyperplasia aged 80 years and over were admitted in our hospital from January 2005 to January 2009.56 cases were treated with transurethral plasmakinetic resection of benign prostatic hyperplasia,and 4 cases were treated with suprapubic prostatic hyperplasia enucleation.IPSS score,residual urine volume and maximum urinary flow rate (Qmax) in all patients were compared between pre-and post-surgery.Results 60 cases of patients were operated successfully without significant intraoperative capsular perforation,ureteral orifice and urethral sphincter injury.IPSS scores and residualurine volume were significantly less after surgery than before surgery [(20.3 ± 3.7) vs.(11.5 ± 2.1),(85.1 ± 13.0) ml vs.(37.7±7.9) ml,t=16.02,24.14,both P＜0.05].The maximum flow rate Qmax was significantly higher after surgery than before surgery[(8.7 ± 2.1) ml/s vs.(14.9 ± 3.2) ml/s,t =12.55,P＜0.05].All patients were followed up for 6-12 months.No incontinence and recurrence of benign prostatic hyperplasia were found.Conclusions Transurethral plasmakinetic resection for treatment of benign prostatic hyperplasia is safe and effective in elderly patients,with a low recurrence rate,and is worthy of promoting.

Sexual behavior of HIV-positive men who have sex with men (MSM) are different from the general MSM. HIV-positive men who know their HIV status are more likely to have sex with positive partner and to engage in receptive anal intercourse as a self harm reduction approach than the general MSM. It is important to strengthen behavioral interventions so as to practice safe sexual behavior to prevent HIV transmission and maintain high life quality among HIV-positive MSM.

Combined Modality Therapy ; Heart Failure ; therapy ; Humans ; Integrative Medicine ; Medicine, Chinese Traditional

Objective To evaluate the effects of different interventions on and influencing factors of picky eaters aged 1 to 5 years old.Methods Two hundred and forty-seven individuals were randomly assigned to the Identification and Management of Feeding Difficulties (IMFeD) group (n =147) and the control group (n =100).The IMFeD group received comprehensive guidance once a month,3 times in total;while the control group had traditional eating guidance.Scores of the IMFeD group were compared with the control group.Multivariate method was used for data analysis.Results Behavior scores of the IMFeD group were 4.7 ± 1.1 at baseline and 9.5 ± 2.6 after the intervention ; although behavior scores of the control group were 4.9 ± 1.1 at baseline and 6.6 ± 2.3 following the routine guidance (F =32.99,P ＜ 0.001).Univariate analysis showed that those two interventions significantly affected the outcomes of intervention (x2 =52.76,P ＜0.05).Regression analyses revealed an odds ratio (OR) of 6.171 (95％ confidence interval (CI) 3.652-10.428) or 0.448 (95％ CI:0.264-0.761) for intervention strategy and time with parents during their 1 year.Conclusion Family-based periodicity intervention may play an important role in eating behavior change and should be widely conducted in child health care.

Objective To study the feasibility of retroperitoneal laparoscopic partial nephrectomy. Methods Retroperitoneal laparoscopic partial nephrectomy was performed in 2 cases of renal malignant tumor and 2 cases of renal hamartoma from August to November 2005.After a retroperitoneal working space was established under laparoscope,the diseased kidney was mobilized with a harmonic scalpel.The renal artery and veins and the ureter were exposed and dissected.Then a laparoscopic partial nephrectomy was conducted.During operation a cotton thread was passed around the renal artery to control the blood supply.ResultsAll the operations were successfully accomplished.No conversions to open surgery were required.The operation time was 1.5 h,1.5 h,2 h,and 3 h,respectively.The intraoperative blood loss was 50~180 ml.A renal pedicel blockage for 25 min was needed in 1 case and was not required in the remaining 3 cases. Conclusions Retroperitoneal laparoscopic partial nephrectomy is feasible.

Objective To investigate clinical significance of D-dimer and other easily-obtained laboratory parameters in rapid screening for acute aortic dissection ( AAD). Methods Data of general health, clinical symptoms, white blood cell (WBC) count, serum levels of C-reactive protein (CRP),cardiac troponin Ⅰ (cTn Ⅰ ) and D-dimer in patients with confirmed AAD and acute coronary syndrome (ACS) were retrospectively analyzed. Significance of varied parameters in clinical diagnosis for AAD was evaluated by logistic regression model and their diagnostic values were evaluated by receiver operating characteristics (ROC) curve. Results Serum level of D-dimer increased significantly in patients with type Ⅰ AAD, as compared with that in those with type Ⅱ and type Ⅲ (P = 0. 111 and 0. 002, respectively). D-dimer, WBC and CRP all were independent risk factors for type Ⅰ AAD by logistic regression model fitted,with the largest effect of D-dimer. Analysis by ROC curve with sensitivities and specificities of serum levels of D-dimer and CRP, and WBC count also showed the same results. Conclusions Determination of serum level of D-dimer had significantly diagnostic value for AAD, and can be sued as rapid screening for it if combined with determinations of WBC and CRP.

Capillaries ; Cells, Cultured ; Down-Regulation ; Endothelial Cells ; metabolism ; Humans ; Leptin ; genetics ; metabolism ; Ophiopogon ; chemistry ; Polysaccharides ; pharmacology ; RNA, Messenger ; genetics ; metabolism