Combined Modality Therapy ; Heart Failure ; therapy ; Humans ; Integrative Medicine ; Medicine, Chinese Traditional

Beijing University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medi-cine, Guangzhou University of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Nanjing University of Traditional Chinese Medicine, and Chengdu University of Traditional Chinese Medicine served as the study object in this study.Their published patent data were recorded and analyzed in terms of the number and types of patent applications, the number of validated patents, and the distribution of patent technologies using the patent information service platform on China Intellectual Property Right Net in order to understand their scientific research level, innovative ability, and scientific research trends.Certain suggestions were put forward for the solu-tion of existing problems and for working out strategies for the protection of intellectual property right.

Angina, Unstable ; therapy ; Angioplasty, Balloon, Coronary ; China ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Myocardial Infarction ; therapy ; Phytotherapy

OBJECTIVETo study the effect of Jiangya Tongmai Recipe (JYTMR), a Chinese herbal medicine preparation for activating blood circulation to remove stasis, on vascular activating substances in treating patients of hypertension with left ventricular hypertrophy.

METHODSThe 37 patients with hypertension were randomly divided into two groups, the treated group (n = 21) and the control group (n = 16). They were treated with JYTMR and captopril respectively for 8 weeks. Left ventricular mass weight (LVMI), peak flow velocity of early diastole (Emax), peak flow velocity of atrial contraction (Amax), Emax/Amax, ejection fraction (EF), as well as levels of plasma endothelin (ET), calcitonin gene-related peptide (CGRP) and angiotensin II (Ang II) were measured before and after treatment and compared.

RESULTSJYTMR could enhance the left ventricular dilation and contractile functions, lower the levels of plasma ET and Ang II and increase the level of plasma CGRP.

CONCLUSIONJYTMR shows good effect in improving left ventricular function and regulating vascular activating substances, it could prevent and treat hypertension and its complications for prolonged treatment via multiple paths and links.

Adult ; Angiotensin-Converting Enzyme Inhibitors ; therapeutic use ; Calcitonin Gene-Related Peptide ; blood ; Captopril ; therapeutic use ; Drugs, Chinese Herbal ; therapeutic use ; Endothelins ; blood ; Female ; Humans ; Hypertension ; blood ; drug therapy ; physiopathology ; Hypertrophy, Left Ventricular ; blood ; drug therapy ; physiopathology ; Male ; Middle Aged ; Phytotherapy ; Ventricular Function, Left ; drug effects

Objective To study the therapeutic effects of extracorporeal shock wave therapy (ESWT) on temporomandibular joint disorders (TMDs).Methods Sixty patients with a temporomandibular joint disorder were randomly divided into an ESWT group and a control group,each of 30.Both groups were given routine rehabilitation training,but the treatment group additionally received ESWT for 2 weeks.Fricton's index was used to evaluate temporomandibular joint function.The subjects used a visual analogue scale (VAS) to evaluate their pain levels.The SF-36 scale was applied to assess their life quality.Results After two weeks of treatment,the average assessment score and VAS score had decreased significantly in both groups.After treatment the average scores for mandibular movement,muscle palpation,joint noise and joint palpation,and the palpation,dysfunction and craniomandibular indexes were all significantly lower in the ESWT group than in the control group.Significant differences were also found in the average VAS scores and on the social functioning domain of the SF-36 between the ESWT group and the control group.Conclusion ESWT combined with rehabilitation training can significantly relieve the symptoms and pain of TMDs.

Drug Therapy, Combination ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Integrative Medicine ; Medicine, Chinese Traditional ; Phytotherapy

Objective To study the method of obtaining a large number of dendritic cells (DC). To study the specific cytotoxicity T lymphocyte (CTL) effect against tumor cells initiated by DC pulsed with peptide of cancer cell. Methods Development of cells with cytologic features of DC in bone marrow cultures supplemented with granulocyte macrophage-colony stimulus factor (GM-CSF) and IL-4. Determining the DC phenotype and the specific structure by electronic microscopy. The CTL effect against pancreatic carcinoma leading by the DC pulsed with tumor cells lysate in vitro was observed. Results A large number of typical DC was proliferated by supplementing with GM-CSF and IL-4 cytokines. DC had specific cell appearance and structure, and highly expressed various cell surface molecules. TNF-? had the ability of stimulating DC mature, the mature DC had the enhancing abilities of antigen presenting and IL-12 self-secreting, as well as, expressed higher levels of CD54, MHC-Ⅱ and CD86 molecules than control group (P

Objective To explore the effects of motor imaginary therapy combined with occupational therapy on the function of upperlimbs hands and activities of daily living for stroke patients with hemiplegia. Methods 62 stroke patients with hemiplegia were divided intoobservation group (n=31) and control group (n=31). Both groups were treated with basic medication and occupational therapy while the observationgroup was treated additionally with motor imaginary therapy. The function of upper limbs and hands was assessed by Fugl-MeyerAssessment (FMA), and activities of daily living was assessed by Functional Independence Measurement (FIM) before and 2 months aftertreatment. Results There were significant difference between the two groups in the scores of FMA in the function of upper limbs and hands,and FIM 2 months after the treatment (P<0.01). Conclusion Motor imaginary therapy combined with occupational therapy can effectivelyimprove the functional outcomes of upper limbs and hands for stroke patients with hemiplegic, and can even effectively improve the functionalactivities of daily living.

Animals ; Education, Medical ; trends ; Humans ; Medicine, Chinese Traditional ; methods ; trends

Animals ; Complementary Therapies ; Drugs, Chinese Herbal ; administration & dosage ; therapeutic use ; Humans ; Injections, Intravenous ; Myocardial Infarction ; physiopathology ; therapy ; Myocardial Reperfusion ; methods ; Ventricular Remodeling ; drug effects