1.Research progress of Kangai injection in the treatment of lung cancer
Cancer Research and Clinic 2014;26(2):136-139
In recent years,the research of Kangai injection,which is one of TCM anti-tumor injections,has been recognized as the most active areas of tumor treatment.To lung cancer patients,solo Kangai injection therapy could improve their quaility of life.It can also increase the efficiency,enhance the immune function,decrease the incidence of toxicities and adverse reactions when it has been combined with chemotherapy or radiotherapy.Overall,Kangai injection is effective in improving therapeutic effect and reducing side-effects of chemotherapy or radiotherapy.This article will discuss about recent research status of Kangai injection in the treatment of lung cancer.
2.An analysis of prognosis risk factors in sever acute epiglottitis
Chinese Journal of Emergency Medicine 2016;25(7):915-919
Objective To confirm the risk factors of poor prognosis in patients with severe acute epiglottitis by comparing symptoms and results of laboratory tests.Methods A total of 698 patients with acute epiglottitis from outpatient and emergency room from 1995 to 2014 were retrospectively studied.These patients were divided into severe or mild group as per the means of treatment of airway including invasive (n =115)and non-invasive (n =583).The past history,general conditions and laboratory tests were compared between the two groups by chi-square or t test;the spearman correlation between the degree of dyspnea and epiglottis edema was analyzed,and the risk factors of poor prognosis were detected by logistic regression.Results The ratio of male to female was 1.366/1.There was a high prevalence of sever acute epiglottitis in spring,winter and at night, respectively.More smokers were found in the severe group compared with the mild group (χ2 =41.957,P <0.01).Severe dyspnea and low PaO2 (r =0.573,P <0.01),but not the poor grading of epiglottis edema evaluated by pharyngo-fiberoscope (r =-0.024,P =0.525),were correlated with poor prognosis.Male (OR =1.84,95%CI:1.41 -3.22,P =0.001),an attack at night (OR =2.61,95%CI:1.98 -3.16),P =0.07), smoker (OR =1.63,95%CI:1.05 -3.39,P =0.04)and low PaO2 (OR =2.97,95%CI:1.58 -4.49,P =0.02)were independent risk factors for a poor prognosis.Conclusions Male,an attack at night,smoker and low PaO2 were independent risk factors for a poor prognosis of acute epiglottitis.A critical care should be given to patients with those risk factors,even their epiglottis edema was not very serious.
3.Sexual behavior and risk factors of HIV-positive men who have sex with men:a review
Chinese Journal of AIDS & STD 2006;0(02):-
Sexual behavior of HIV-positive men who have sex with men (MSM) are different from the general MSM. HIV-positive men who know their HIV status are more likely to have sex with positive partner and to engage in receptive anal intercourse as a self harm reduction approach than the general MSM. It is important to strengthen behavioral interventions so as to practice safe sexual behavior to prevent HIV transmission and maintain high life quality among HIV-positive MSM.
5.Surgical treatment of benign prostatic hyperplasia in elderly patients
Chinese Journal of Geriatrics 2014;33(2):169-171
Objective To investigate the clinical efficacy of surgery treatment of benign prostatic hyperplasia in elderly patients.Methods 60 elderly patients with prostatic hyperplasia aged 80 years and over were admitted in our hospital from January 2005 to January 2009.56 cases were treated with transurethral plasmakinetic resection of benign prostatic hyperplasia,and 4 cases were treated with suprapubic prostatic hyperplasia enucleation.IPSS score,residual urine volume and maximum urinary flow rate (Qmax) in all patients were compared between pre-and post-surgery.Results 60 cases of patients were operated successfully without significant intraoperative capsular perforation,ureteral orifice and urethral sphincter injury.IPSS scores and residualurine volume were significantly less after surgery than before surgery [(20.3 ± 3.7) vs.(11.5 ± 2.1),(85.1 ± 13.0) ml vs.(37.7±7.9) ml,t=16.02,24.14,both P<0.05].The maximum flow rate Qmax was significantly higher after surgery than before surgery[(8.7 ± 2.1) ml/s vs.(14.9 ± 3.2) ml/s,t =12.55,P<0.05].All patients were followed up for 6-12 months.No incontinence and recurrence of benign prostatic hyperplasia were found.Conclusions Transurethral plasmakinetic resection for treatment of benign prostatic hyperplasia is safe and effective in elderly patients,with a low recurrence rate,and is worthy of promoting.
7.Retroperitoneal laparoscopic partial nephrectomy: A report of 4 cases
Rongjiang WANG ; Shuo WANG ; Sihai SHAO
Chinese Journal of Minimally Invasive Surgery 2001;0(03):-
Objective To study the feasibility of retroperitoneal laparoscopic partial nephrectomy. Methods Retroperitoneal laparoscopic partial nephrectomy was performed in 2 cases of renal malignant tumor and 2 cases of renal hamartoma from August to November 2005.After a retroperitoneal working space was established under laparoscope,the diseased kidney was mobilized with a harmonic scalpel.The renal artery and veins and the ureter were exposed and dissected.Then a laparoscopic partial nephrectomy was conducted.During operation a cotton thread was passed around the renal artery to control the blood supply.ResultsAll the operations were successfully accomplished.No conversions to open surgery were required.The operation time was 1.5 h,1.5 h,2 h,and 3 h,respectively.The intraoperative blood loss was 50~180 ml.A renal pedicel blockage for 25 min was needed in 1 case and was not required in the remaining 3 cases. Conclusions Retroperitoneal laparoscopic partial nephrectomy is feasible.
8.Effect of clinical intervention on and influencing factors of young picky eaters
Shuo WANG ; Xiaona HUANG ; Huishan WANG
Chinese Journal of Health Management 2013;(3):155-158
Objective To evaluate the effects of different interventions on and influencing factors of picky eaters aged 1 to 5 years old.Methods Two hundred and forty-seven individuals were randomly assigned to the Identification and Management of Feeding Difficulties (IMFeD) group (n =147) and the control group (n =100).The IMFeD group received comprehensive guidance once a month,3 times in total;while the control group had traditional eating guidance.Scores of the IMFeD group were compared with the control group.Multivariate method was used for data analysis.Results Behavior scores of the IMFeD group were 4.7 ± 1.1 at baseline and 9.5 ± 2.6 after the intervention ; although behavior scores of the control group were 4.9 ± 1.1 at baseline and 6.6 ± 2.3 following the routine guidance (F =32.99,P < 0.001).Univariate analysis showed that those two interventions significantly affected the outcomes of intervention (x2 =52.76,P <0.05).Regression analyses revealed an odds ratio (OR) of 6.171 (95% confidence interval (CI) 3.652-10.428) or 0.448 (95% CI:0.264-0.761) for intervention strategy and time with parents during their 1 year.Conclusion Family-based periodicity intervention may play an important role in eating behavior change and should be widely conducted in child health care.
9.Effects of eyes movement training on event-related potentials of visual attention of mid cognitive impairment patients
Shuo WANG ; Xiuyan LI ; Mengmeng SU
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(4):345-347
Objective To study the visual attention of mild cognitive impairment patients (MCI)by eyes movement training. Meathods 48 mild cognitive impairment patients were divided into eye movement training group,finger training group and untreated control group by single-blind randomized block method. Then they were trained respectively three months. Event-related potentials (ERPs) were used to measure the face recognition of them before and after training. The amplitude and latency of P3b elicited by target stimuli and P3a elicited by new stimuli of the three said groups were compared and contrasted. Results After training,the amplitude of P1 elicted by novelty stimulus were larger in eye movement training group( (6.78 ± 1.55 ) μV) and in finger training group ( ( 5.43 ± 1.47 ) μV) than untreated control group ( ( 3.09 ± 0.98 ) μV) significantly, especially in the frontal area. The amplitude of P1 elicted by target stimulus were larger in eye movement training group( (6.75 ±2.01 ) μV)than in finger training group( (4.12 ± 1.33 )μV)and untreated control group( (3.45 ± 1.01 )μV)significantly, especially in the frontal area. The amplitude of P3a were larger in eye movement training group( ( 10. 19 ± 3.09)μV ) than in finger training group ( ( 7.57 ± 2.66 ) μV ) and untreated control group ( ( 6.06 ± 2.03 ) μV ) (P < 0.05,P<0.05) significantly,especially in the frontal area. The latency of P3a were earlier in eye movement training group( (390.67 ±55.03 ) ms) compared to finger training group( (428.55 ± 48.68 ) ms) and untreated control group( (435.89 ± 59.21 )ms)significantly, especially in the frontal region and central parietal area. Conclusion Eyes movement can improve the MCI patients' non-selective attention function, especially in frontal area.The finger execrises have no significant effect on visual attention.
10.Laparoscopic radical prostatectomy: A report of 10 cases
Shuo WANG ; Liping XIE ; Danbo FANG
Chinese Journal of Minimally Invasive Surgery 2001;0(06):-
Objective To study the feasibility of transperitoneal laparoscopic radical prostatectomy. Methods Laparoscopic radical prostatectomy was performed according to Montsouris technique. Results All the operations were successfully completed. The operating time was 330~540 min (mean, 433 min) and the estimated blood loss was 100~550 ml (mean, 274 ml). No patients required a blood transfusion. Bladder injury was found in 1 patient and was sutured promptly during the operation. The postoperative hospital stay was 15~23 days (mean, 17 days). The catheterization time was 14~23 days (mean, 16 days). In 2 patients presenting with urinary leakage, the catheter was removed at 20 and 23 days after surgery respectively, while in the remaining 8 patients, at 2 weeks after operation. Mild urinary incontinence occurred in 3 patients and disappeared after 4 weeks of supportive treatment. Pathological examinations revealed stage pT_ 1c) in 3 patients, stage pT_2 in 6, and stage pT_3 in 1. A follow-up for 3~21 months (mean, 7.5 months) was carried out. The postoperative prostate-specific antigen (PSA) level was 0~2.70 ?g/L(mean,0.05 ?g/L). Two patients returned a normal sexual function. Conclusions Strict following surgical indications, adequate preoperative preparation, improvement of surgical techniques, and proper application of surgical instruments and devices make transperitoneal laparoscopic radical prostatectomy feasible.