1.Hospital Infection among Psychiatric Inpatients in State of Protective Constraint
Zhengping CHEN ; Xiaohua CHEN ; Shunquan WANG
Chinese Journal of Nosocomiology 2006;0(12):-
OBJECTIVE To explore the affection of protective constraint on infection among psychiatric inpatients and it′s preventive methods.METHODS A retrospective study of infection among psychiatric patients was carried by medical records investigation.Inpatients in states of protective constraint and non-constraint in confining units of psychiatric department were divided into study group and control group.Case-control study was carried up on rate of hospital infection and rate of infection of parts of body between groups.RESULTS The infective rate of study group was significantly higher than control one,in which,infective rates of lower respiratory tract,urinary tract,dermatological and mucous parts of study group were significantly higher than control group.CONCLUSIONS Protective constraint for psychiatric patients is one of risk factors of hospital infection,to which should be pay attention,and preventive methods might be taken.
2.The diagnoses of mental disorder in ShaoXing city
Shunquan WANG ; Zhengping CHEN ; Xiaohua CHEN
Chinese Journal of Rehabilitation Theory and Practice 2005;11(6):489-491
ObjectiveTo investigate the incidence of the intense mental disorder of the diagnosed population, prepared for the prevention and cure of psychosis in the community.MethodsAn national prevention and cure of psychosis table was carried out family by family to diagnose, with the group consisted of the leader of village, psychiatrists, doctors being engaged in the prevention and cure of mental disorders, cadre of village.ResultsIn the 1528133 population, 10266 were diagnosed as mental patients, with the rate of diagnosis of 6.72‰. Of that non-therapists were 6649, account for 64.77%; in the 3617 ever-therapists, 2487 had ever recurred, with the recurrcence rate of 68.76%.ConclusionThe prevention and cure and scientific research of psychosis should be paid more attention.
3.The establishment of HCV IgG antibody chemiluminescence detection method and preliminary application
Jun HOU ; Yan HU ; Shunquan WU ; Bingke BAI ; Qiyu JIANG ; Sujuan SHI ; Baojun WANG ; Weijun OU ; Panyong MAO
Chinese Journal of Laboratory Medicine 2015;(3):159-162
Objective To establish a chemiluminecentdetection method ( CLIA ) of HCV IgG antibody for the detection of HCV infection and therefore lay a foundation for the research and development of testing kit.Methods Based upon the indirect ELISA method, the microwell plate was coated with HCV-NS3 and HCV-Core antigen expressed through gene engineering, and the anti-human IgG antibody was labeled with horse radish peroxidase.In this way, the chemiluminesent detection method of HCV IgG antibody was established.Meanwhile, the serum specimen of randomly selected 198 patients infected with HCV from No.302 Hospital of PLA and 222 blood donors, and the results were compared.Results The HCV-IgG antibody, a positive consistent rate of 99.0%( 196/198 ) , a negative consistent rate of 98.2%(218/222), and a total consistent rate of 98.6%(414/420) were found through testing 420 serum specimen with self-made agent and contrast agent.One HCV positive serum was repetitively tested with the self-made agent for 10 times, and a coefficient of variation ( CV) of less than 10% was found.Conclusion The chemiluminescent detection method of HCV IgG antibody is initially established, and the method, with an outstanding specificity and sensitivity, is applicable for screening blood donors, clinically detecting HCV infection as well as epidemiological survey.
4.Efficacy and safety of tandem autologous stem cell transplantation in multiple myeloma: a retrospective single-center analysis.
Shunquan WU ; Zongjian QIU ; Ting LIN ; Zhijuan ZHU ; Xiaofan LI ; Xianling CHEN ; Ping CHEN ; Yiting WANG ; Rong ZHAN ; Nainong LI
Chinese Medical Journal 2023;136(15):1873-1875