Objective　In a RCT study, the safety and efficacy of sabot (a slow-release salbuteral) and volmax (controlled-release salbuterol) were compared in bronchial asthma. Methods　40 patients with moderate to severe asthma were randomly divided into two groups and treated by sabot or volmax for 2 weeks. The FEV1%, peak expiratory flow (PEF), symptom score and use of rescue ventolin were measured to evaluate the effect of treatment. Results　After treatment FEV1%, PEF and symptom score improved and the need for inhaling short-acting beta 2-agonis in both groups reduced significantly. There was no difference of these improvement between two groups. Conclusion　The safety and efficacy of sabot for treatment of asthma was similar to volmax.

Objective To investigate the pathological change in articular cartilages after firearm injury.Methods Four rabbits from 28 New Zealand healthy rabbits were chosen as control group and subjected to joint capsule incision only. Another 24 rabbits were equally divided into 6 experimental groups( groups B to G) and subjected to medial femoral condyle cartilage surface damage by the nail gun.After the operation, their specimens were collected after 6 h,3 d,7 d,14 d,28 d and 56 d, respectively.Tissue sections were observed and stained by HE staining and toluidine blue staining.The histolopathological changes in articular cartilage after firearm injury were detected.Results The color of articular cartilages in experimental groups became lighter, the cell number increased but then decreased, the articular cartilage layer disappeared, the cell shape became uneven, cells began to cluster and the Mankin score increased, and the statistical differences between experimental groups and control group were significant.Conclusion The histological pathological changes in articular cartilages after fiream injury seem to follow some pattern.The degeneration seems obvious after 7 days and then becomes heavier.

Objective:The treatment of Tossy type Ⅲ acromioclavicular joint dislocation with clavicular hook plate combined with coracoclavicular ligament repair, and to explore its clinical effect.Methods:80 patients with Tossy type Ⅲ acromioclavicular joint dislocation who were admitted to our hospital from January 2014 to January 2019 were selected. They were randomly divided into control group ( n=39, treated with clavicular hook plate) and study group ( n=41, treated with clavicular hook plate combined with coracoclavicular ligament repair) by number table method. The clinical efficacy at 12 months after operation, related clinical indicators, recovery at 12 months after operation and complications after operation were compared between the two groups. Results:The excellent and good rate was 92.68% in the study group at 12 months after operation, which was higher than 76.92% in the control group ( P<0.05). There were no significant differences in operation time, intraoperative bleeding volume and hospital stay between the study group and the control group ( P>0.05). At 12 months after operation, the abduction activity and flexion activity of the study group were higher than those of the control group, and the visual analogue score (VAS) score was lower than that of the control group ( P<0.05). The incidence of complications in the study group was slightly lower than that in the control group, but there was no significant difference between the two groups ( P>0.05). Conclusions:For Tossy type Ⅲ acromioclavicular joint dislocation, clavicular hook plate combined with coracoclavicular ligament repair has a good clinical effect. It can improve shoulder joint function, alleviate shoulder pain, and have fewer complications. It can provide a reference for clinical treatment of this type of acromioclavicular joint dislocation.

Aiming at the problem of low recognition accuracy of motor imagery electroencephalogram signal due to individual differences of subjects, an individual adaptive feature representation method of motor imagery electroencephalogram signal is proposed in this paper. Firstly, based on the individual differences and signal characteristics in different frequency bands, an adaptive channel selection method based on expansive relevant features with label F (ReliefF) was proposed. By extracting five time-frequency domain observation features of each frequency band signal, ReliefF algorithm was employed to evaluate the effectiveness of the frequency band signal in each channel, and then the corresponding signal channel was selected for each frequency band. Secondly, a feature representation method of common space pattern (CSP) based on fast correlation-based filter (FCBF) was proposed (CSP-FCBF). The features of electroencephalogram signal were extracted by CSP, and the best feature sets were obtained by using FCBF to optimize the features, so as to realize the effective state representation of motor imagery electroencephalogram signal. Finally, support vector machine (SVM) was adopted as a classifier to realize identification. Experimental results show that the proposed method in this research can effectively represent the states of motor imagery electroencephalogram signal, with an average identification accuracy of (83.0±5.5)% for four types of states, which is 6.6% higher than the traditional CSP feature representation method. The research results obtained in the feature representation of motor imagery electroencephalogram signal lay the foundation for the realization of adaptive electroencephalogram signal decoding and its application.
Humans ; Imagination ; Signal Processing, Computer-Assisted ; Brain-Computer Interfaces ; Electroencephalography/methods* ; Imagery, Psychotherapy ; Algorithms