Objective To investigate the effects of physical exercises on cardiac function and plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in hypertensive patients combined with diastolic cardiac dysfunction.MethodsA total of 66 essential hypertension patients who had abnormal left ventricular relaxation and normal systolic function were assigned to the intervention group ( n =33 ; doing physical exercises once a day,5 days a week) or control group (n =33 ).All the patients received standard treatment.At 6 months,body weight,blood pressure,heart rate,NT-proBNP,and echocardiography were measured.ResultsAt 6 months,body weight [ (68 ± 7 ) kg vs (72 ± 8 ) kg ],systolic blood pressure [ (135.4 ±5.1) mm Hg (1 mm Hg =0.133 kPa) vs (141.9 ±5.2) mm Hg ],diastolic blood pressure [ (81.1 ±4.0) mm Hg vs (84.7 ±4.6) mm Hg],New York Heart Association class (1.4 ±0.3 vs 1.8 ±0.4),NT-proBNP level [ (526 ± 126 ) ng/L vs (741 ± 189 ) ng/L] were significantly decreased in the intervention group when compared with the control group ( all P ＜ 0.05 ) although left ventricular ejection fraction (LVEF) (62.9 ±6.7 vs 59.0 ±5.6) and E/A ratio ( 1.1 ±0.3 vs 0.9 ±0.3) were significantly increased ( both P ＜ 0.05).ConclusionPhysical exercises could play a role in reduced blood pressure and body weight and improved cardiac function in hypertensive patients with diastolic cardiac dysfunction.

Objective:To explore the mediating effect of medical coping style on psychological resilience and death anxiety in cancer patients.Methods:Using the convenient sampling method, a total of 330 inpatients from 2 cancer hospitals in Beijing were selected as the research objects from June to August 2020. The general information questionnaire, Chinese Version of Templer 's Death Anxiety Scale (C-T-DAS) , Medical Coping Modes Questionnaire (MCMQ) and the Connor-Davidson Resilience Scale (CD-RISC) were used to investigate them. Pearson correlation analysis and multiple linear regression were used to analyze the relationship between death anxiety, medical coping style and psychological resilience in cancer patients. AMOS 21.0 was used to establish the structural equation model and verify the mediation effect. A total of 330 questionnaires were sent out in this study, and 302 were effectively received, with the effective recovery of 91.5%. Results:The score of Chinese Version of Templer's Death Anxiety Scale for 302 cancer patients was (40.12±10.23) , the score of Connor-Davidson Resilience Scale was (70.97±13.43) and the scores of confrontation, avoidance and resighation dimension of Medical Coping Modes Questionnaire were (18.80 ±3.65) , (15.64±3.16) and (8.75±2.84) . The psychological resilience of cancer patients was negatively correlated with death anxiety and the resignation dimension in medical coping styles ( P<0.01) , and positively correlated with the facing and avoiding dimensions in medical coping styles ( P<0.05) . The face and yield dimensions in the medical coping style of cancer patients were positively correlated with death anxiety ( P<0.05) . Medical coping styles played a partial mediating role between psychological resilience and death anxiety, and the mediating effect accounted for 32.47% of the total effect. Conclusions:Clinical medical staff should pay attention to the death anxiety of cancer patients, improve their psychological resilience and encourage patients to actively cope with the disease, so as to reduce their death anxiety level and promote mental health.

Cardio-oncology is an emerging cross-discipline， which has received extensive attention and rapid development at home and abroad in recent years， while the construction of related disciplines in the field of traditional Chinese medicine （TCM） is still in its initial stage. By sorting out the construction of oncology and cardiology related disciplines at home and abroad at this stage， and clarifying the significance and main research contents of the discipline， it is proposed that the construction of TCM related disciplines should be oriented to the four main aspects， including clinical practice， scientific research， talent training and promotion of cultural characteristics. Therefore， actively carrying out multidisciplinary crossing， cultivating related professional talent team， and forming TCM diagnosis and treatment guidelines or consensus to support clinical practice is the essential foundation for the construction of TCM cardio-oncology discipline. Meanwhile， fully exploring the characteristics and advantages of TCM is the key to the construction process of the discipline， such as writing and summarising and analysing relevant high-quality clinical case reports of TCM for evidence-based optimisation， as well as widely applying the concept of "treating disease before it arises" of TCM characteristics to the clinical prevention and treatment of the relevant diseases and scientific research， etc.， so as to comprehensively guarantee the development of the discipline of TCM cardio-oncology.