1.Image reconstruction of positron emission tomography
Chinese Journal of Medical Physics 2000;17(4):197-200
As the great progress in computer technology, the image reconstruction of PET has been extensively studied, especially the fast methods being able to suppress the noise and meanwhile improve spatial resolution. This paper gives a brief description of the principle and research status of PET reconstructions, and that of 3D PET as well.
2.Real-time energy correction in digital gamma camera
Chinese Medical Equipment Journal 1989;0(04):-
This paper introduces the generating principle of energy correction table for digital gamma camera and elaborates a method for real-time energy correction. According to the position information of the collected events, correction cells are determined. With the correction value in four adjacent correction cells, coefficient of energy correction is worked out through bilinear interpolation. Finally, real-time energy correction for the collected events is achieved through software programming.
3.Research progress of SPARC in esophageal cancer
Haibo HUANG ; Yan ZHAO ; Shujun YANG
Journal of International Oncology 2014;41(12):918-921
Secreted protein acidic and rich in cysteine (SPARC) is expressed in esophageal cancer abnormally.On the one hand,recent studies show that high SPARC expression is correlated with progression and metastasis of esophageal cancer.On the other hand,high SPARC expression increases chemosensitivity and improves short-term efficacy in patients.
4.Lymphangiogenesis factor in the lymph node metastasis of head and neck cancer
Shujun SUN ; Limin ZHAO ; Jianming ZHOU
Journal of International Oncology 2011;38(7):509-512
Early lymph node metastasis is a common clinical phenomenon in many human cancers, which is associated with both aggressive disease and poor prognosis. Clearly, treatments to specifically block dissemination through the lymphatic network would be desirable either as independent therapies or as adjuncts to existing chemotherapy. At the present stage the target vessels for invasion by lymph-metastasizing tumor cells include preexisting tissue lymphatics abutting the tumor mass through either coincidence or mutual chemoattraction, as well as new lymphatic vessels that proliferate either within or around the tumor as a result of lymphangiogenesis. The lymphangiogenesis is regulated primarily by the lymphangiogenic growth factors VEGF-C and VEGF-D generated by tumor cells or host cells including tissue macrophages. Nevertheless, it remains controversial as to whether this metastasis-enhancing effect simply results from an increase of the number of target vessels due to mitogenesis or from other properties of the newly dividing tumor lymphatics.
5.An epidemiologic analysis of maxillofacial injuries resulted in different causes
Shujun LI ; Yanpu LIU ; Jinlong ZHAO
Medical Journal of Chinese People's Liberation Army 2001;0(08):-
Objective To analyse the characteristics of maxillofacial injuries resulted in different causes. Methods A retrospective review was done of patients admitted to the Stomatology Hospital of Fourth Military Medical University from January, 1996 to July, 2003. Data was grouped by different causes. Results 1 188 patients were reviewed, the majority of victims caused by different causes were males, the ratio of male and female is 3.34∶1. Most industrial and sport injury occurred in men. Traffic accidents were the major cause of the midface fracture and mandibular fracture. While violence was the major cause of pure soft injure and alveolar bone fracture. Conclusions Traffic accidents and violence were the major causes of facial injury. The facial injury caused by traffic accidents, industrial accidents and fall was more serious than those caused by other causes. More emphasis should be put on the prevention and treatment of these injuries to minimize the maxillofacial malformation.
6.Surgical treatment of recurrent gastric carcinoma
Yuting ZHAO ; Zhan SONG ; Shujun ZHANG
Journal of Clinical Surgery 2001;0(03):-
Objective To investigate the surgical indicatin and outcome of recurrent gastric carcinoma.Methods Review the clinical data of 56 cases with recurrent gastric carcinoma underwent reoperation from 1990 to 2000.The operative indication, surgical method and complications were analized.Results In 25 cases the recurrent tumor were resected (44.6%),in 10 cases adjacent organs were resected.NO operative motality was observed.Conclusions More aggressive radical resection of the gastric cancer is the key to prevent recurrence.Laparotomy should be performed without delay once there is a suspicion of recurrence.
7.Betatrophin and glucose-lipid metabolism
Shujun ZHAO ; Mingming WANG ; Shiwei LIU
Chinese Journal of Endocrinology and Metabolism 2015;31(3):288-290
Betatrophin,discovered in 2013,is a protein secreted by liver,white adipose tissues,and brown adipose tissues.Betatrophin can improve glucose tolerance in mice by promoting islet β cell proliferation and increasing the number of β cells significantly and specifically.At the same time,Betatrophin is involved in lipid metabolism.Betatrophin may work as the new target for treatment of diabetes and disorders of lipid metabolism.
8.Characteristics and clinical values of SPECT/CT whole-body bone scanning in detecting bone metasta-ses in patients with lung adenocarcinoma or squamous cell carcinoma
Shujun LIANG ; Bin ZHAO ; Shaojun ZHOU ; Yan SUN ; Yuxiang WANG
Journal of International Oncology 2015;(6):407-409
Objective To investigate the clinical values and characteristics of whole body bone ima-ging (SPECT/CT)in detecting bone metastases in the preoperative patients with lung adenocarcinoma or squa-mous cell carcinoma for staging and determining the best treatment plan.Methods Eighty-two preoperative patients with primary pulmonary adenocarcinoma or squamous cell carcinoma performed 99 Tcm-MDP SPECT/CT whole-body bone imaging.One week before surgery,parts of positive lesions performed MRI scan.The differ-ence of the incidence of bone metastasis was analysed by χ2 test.Results In all 82 patients with lung cancer, there were 38 adenocarcinomas and 44 squamous cell carcinomas.Bone metastases were detected in 38 cases, the incidence rate was 46.3%.Of which,among lung adenocarcinoma,the incidence rate was 57.9% (22 /38),and the incidence rate was 36.4% (1 6 /44)in lung squamous cell carcinoma,and the difference was sta-tistically significant (χ2 =1 2.66,P =0.027).The most common area was bilateral ribs,followed by vertebra, pelvis,bones of the extremities and skull.Conclusion Lung adenocarcinoma compared with squamous cell carcinoma is prone to bone metastases,and bone metastases are more common in bilateral ribs.It has important value that whole body bone imaging in screening for bone metastases of pre-operative patients with lung cancer for staging and making the treatment plan.
9.Oxaliplatin combined with tegafur as adjuvant chemotherapy for esophageal squamous cell carcinoma
Haibo HUANG ; Kai LIU ; Haiying WANG ; Yan ZHAO ; Shujun YANG
Cancer Research and Clinic 2015;27(2):103-106
Objective To investigate the survival benefit of patients with esophageal squamous cell carcinomas who recieved postoperative chemotherapy of tegafur combined with FT-207 radiotherapy.Methods Data from 126 patients with esophageal squamous were analyzed who undergone radical resection from January 2008 to December 2010,consisting of 92 patients underwent surgery alone and 34 patients took oxaliplatin combined with tegafur postoperatively (oxaliplatin 130 g/m2,d1,tegafur 500 mg/m2,d1-5,21 d for a cycle,every patient received at least two cycles).Results The 1-year survival rate and 3-year survival rate was 93.5 % and 75.0 % in the surgery alone group,was 97.1% and 76.2 % in the surgery plus postoperative chemotherapy (P =0.590).There was no significant differences in survival in the two groups,even with Coxregression multivariate analysis and with stratifications of gender,age,tumor location,degree of cell differentiation,invasion depth,lymphatic metastasis and TNM stage.Conclusion Postoperative adjuvant chemotherapy with oxaliplatin combined with tegafur has not significantly improve the survival rate of patients with esophageal squamous cell carcinomas undergoing radical resection.It is still lack of an effective project for postoperative adjuvant chemotherapy for esophageal cancer,and it is necessary for further study.
10.Advances of quantitative analysis methods on diffusion tensor imaging
Binbin NIE ; Jingjing ZHAI ; Lijing WANG ; Shujun ZHAO
Chinese Journal of Medical Imaging Technology 2010;26(3):581-584
Quantitative analysis on diffusion tensor imaging is prerequisite. The arithmetic of statistical analysis was reviewed in this article via analyzing the arithmetic of quantitative parameters and fiber track on diffusion tensor imaging.