Objective To explore the significance of interleukin -35 (IL -35)in serum of patients with severe hepatitis.Methods Collected 39 cases of chronic hepatitis B(CHB)patients and severe hepatitis,and col-lected 19 cases of healthy control's(HC)peripheral blood at the same time.ELISA method was used to detect IL -35 levels.Results IL -35 in CHB and severe hepatitis group [(483.5 ±280.7)ng/mL and (277.9 ±248.7)ng/mL] were higher than HC group (50.5 ±47.8)ng/mL(t =2.089,3.303,P =0.044,0.002).In severe hepatitis group, the IL -35 levels in survivors group (305.3 ±301.2)ng/mL was higher than death group (78.7 ±33.2)ng/mL (P =0.012).IL -35 was positively correlated with ALT and AST,the correlation coefficient were 0.649 and 0.599. Conclusion IL -35 is involved in the pathogenesis of hepatitis B process,the low serum IL -35 levels in severe hepatitis patients may herald a bad prognosis.

Medical image registration is a key step of image processing and analysis and the first problem of medical image fusion to be solved. In this paper, we focus on magnetic resonance images registration for preoperative and postoperative of deep brain stimulation for the Parkinson's disease. First of all, mutual distance is brought into the mutual information in this paper, realize the two groups of MR slices (for both preoperative and postoperative) mapping, and then 3D images are reconstructed from the corresponding MR slices. Finally, we use Powell algorithm to register 3D images. After the 3D images is registered, we can analyze the relative position between planted electrode (postoperative) and the subthalamic nucleus (preoperative), and measure the quality of deep brain stimulation scientifically.
Algorithms ; Deep Brain Stimulation ; methods ; Electric Stimulation ; Humans ; Image Processing, Computer-Assisted ; methods ; Imaging, Three-Dimensional ; Magnetic Resonance Imaging ; methods ; Parkinson Disease ; pathology ; therapy ; Subthalamic Nucleus ; pathology

Objective To study the relationship between cleanliness of children′s hands and diminution of Ascaris lumbricoides infection. Methods Before the study all persons positive for ascaris eggs in the preliminary survey were treated with albendazole. Hand washing habit before meal and after defecation was kept in children of experimental group, but not in the control group. Kato thick smear stool examination was done once every two months for one year to compare the new infection rates in children without ascaris infection in the two groups, and the reinfection rates in the cured negative cases were also compared between them in half a month after chemotherapy. Results All the new infection rates as well as reinfection rates of each reexamination in the experimental group were significantly lower than that of the control group ( P