This paper summarizes the progress in the study on anthelmintics,including nematocide,trematocide and cestocide since the founding of the People′ s Republic of China and the roles that these agents played in the control of parasitic diseases.Meanwhile,views are given to the challenges faced in the further study on anthelmintics.

Praziquantel is the only effective drug of choice against five huaman species of schistosomes. Main adva-ntages of praziquantel include convenient oral administration, high safety and efficacy as well as short treatment course. To better understand the mode of action of praziqantel against schistosomes would be helpful for further development of new broad-spectrum anthelminthics. This paper summarizes the 30 years′ research progress on the mode of action of the drug against schistosomes proceeded by domestic and abroad laboratories.

Objective To discuss the reliability of sensory integration curing and the affecting element of curing result. Method Adopt standardized curing method to 455 children, four to twelve years old, who have sensory integration disorder. Start up parents school as well. Result The total effective rate is 85%. The more parents grasp the children sanitation knowledge, the better results are. The better results are also related to the level of disorder, intelligence quotient, age and curing period. Conclusion Sensory integrating treatment is effective in treating sensory integrating disohter in children by systematic psychological intervention for children and personal psychological intervention for parents.

More than 40 institutions have set up the specialty of medical law in order to train inter-disciplinary talents of medical law.Many scholars undertook extensive research aiming at strengthening and developing this new specialty,but many problems still existed in its teaching and the quality of the graduates was been questioned.Through in-depth analysis of the existing research,we pointed out three problems of the current research:being subjective and lacking data support; confining to the ivory tower and lacking contact with the social; limiting to scholars and teachers and lacking retrospective thinking and critique from postgraduates.

Objective To discuss the clinical curative effect on maxillary sinusitis nasal endoscopic single path surgical treatment and provide reference for the clinical treatment.Methods A total of 52 patients of fungal ball type maxillary sinusitis were randomly divided into group A(26 patients) and group B (26 patients).The patients in group A were treated by endoscopic single path surgical treatment and the patients in group B were treated by intranasal antrostomy.The clinical curative effect was analyzed.Results In group A and group B,the total effective rate was 88.5％(23/26) and 65.4％(17/26),there was significant difference (P ＜0.05).The remission rate of nasal obstruction,nasal discharge with suppuration,nasal discharge with blood,headache were 100.0％ (26/26),92.3 ％ (24/26),84.6％ (22/26),73.1％ (19/26) in group A,and 100.0％(26/26),88.5％(23/26),76.9％(20/26),65.4％(17/26) in group B.The recurrence rate in group A and group B was 0,15.4％(4/26),there was significant difference (P＜ 0.05).Conclusions The clinical curative effect of endoscopic single path surgical treatment is better,and the recurrence rate is lower.It is worthy of clinical application.

Physiological MR imaging techniques provide abundant information for the diagnosis and research of knee cartilage le -sions.It can not only evaluate the morphology and structure of cartilage , but also analyze the functional , metabolic and biochemical changes quantitatively , to explore the causes of cartilage lesions at the molecular level .Application and advance of physiological MR imaging of knee articular cartilage are reviewed , including sodium imaging , delayed gadolinium enhanced magnetic resonance imaging of cartilage, T1ρ, T2 mapping, chemical exchange saturation transfer , diffusion imaging and so on, aiming at providing references for choosing MR imaging of knee articular cartilage .

Objective To evaluate the health effects of ambient air pollution on the respiratory systems of school children and screen the risk factors associated with respiratory diseases in order to propose air pollution control measures and to protect susceptible population. Methods The air pollution monitoring data were obtained from the local environmental protection bureau. Six thousand elementary school pupils (grade 1 and grade 6, half girls and half boys) were selected from light and heavy air pollution areas. Respiratory health states were assessed by investigation of the children's respiratory symptoms and diseases using a parent-completed questionnaire. The results were analyzed by non-conditional logistic regression analysis to calculate ORs of respiratory symptoms and diseases and 95% confidence intervals, after adjustment for air pollution levels, age, sex, indoor coal-burning, parents' smoking, ventilation and parents' respiratory disease history. Results TSP in lightly and heavily air-polluted areas were 0.59 mg/m3 and 1.02 mg/m3 respectively (P

The academic thinking of WU Pei-heng derived from the theory of thinking highly of yang-qi in Inner Canon of Huangdi and the theory of waming yang to support vital qi in Treatise on Febrile Diseases. He considered that the yang-qi was the essence of the life, warming yang and assisting yang was the core of his academic thinking. He was good at using Radix Aconiti Lateralis Preparata with hige dosage. The 4 cases in this article proved the science and practicality of warming yang and assisting yang.

The afferent projections to the head of the caudate nucleus of rat from subcortical nuclei were studied with the method of retrograde axonal transport of horseradish peroxidase (HRP). Experiment were carried out in a series of adult rat. Under pentobarbital sodium anesthesia, 0.2～0.5,?l of 50% solution of HRP was injected slowly into the head of the caudate nucleus of the rat. according to the stereotaxic atlas by Massopust, Jr. After a survival time of 6～72 h, the animals were perfused with fixative solution (1.25% glutaraldehyde and 2.0% paraformaldehyde in 0.1M phosphate buffer, at pH 7.4). The brain was removed and then postfixed in same fixative at 4℃ for 6～18h. The frozen sections were incubated in a medium containing 3, 3′-diaminobenzidine tetrahydrochloride and hydrogen peroxide. The sections were examined microscopically under both bright-field and dark-field illumination. Labelled neurons were found ipsilaterally in the parafascicular nucleus of the thalamus and substantia nigra of the midbrain. They were also found in the dorsal nucleus of the midbrain raphe, mainly ipsilaterally, scantily contralaterally. Statistical examination showed as follows: The substantia nigra of the midbrain has the most labelled neurons, the dorsal nucleus of the midbrain raphe has the least labelled neurons, while the parafascicular nucleus of the thalamus has moderate number of labelled neurons. The afferent projections to the head of the caudate nucleus of the rat from the subcortical nuclei may play the role in the mechanism of pain and pain control.

Two cases of left atrial myxoma were reported and the clinical data of 58 cases in Chinese literature were reviewed with the emphasis to find the characteristics of this disease on x-ray plain films and in the clinical features. The criteria to differentiate this condition from rheumatic mitral stenosis were listed. It is suggested that the diagnosis of left atrial myxoma be considered when the x-ray features of a clinically suspected case of mitral stenosis are not typical and then echocardiography be performed to investigate the case further.