1.Community-based family intervention improves symptom and social function of schizophrenic patients
Jing TANG ; Keming WU ; Dean LIU ; Jianjun LI ; Shubing QIU ; Qing ZHOU ; Xiaolin ZHOU
Chinese Journal of General Practitioners 2013;(3):216-218
One hundred and twenty patients with schizophrenia were randomly divided into intervention group and the control group with 60 in each.Family members in intervention group were given community based-rehabilitation training and education once a month for 12 months.Brief Psychiatric Rating Scale (BPRS) and Social Disability Screening Schedule (SDSS) were used to assess the symptoms and social function of patients before and after intervention.The results were compared between two groups.Results showed that the BPRS total score and the SDSS total score in intervention group were lower than those in control group (P < 0.05).The training and education of family members can improve symptoms and functional recovery for patients with schizophrenia.
2.Determination of Cyromazine and Dicyclanil Residues on Greasy Wool by High Performance Liquid Chromatography
Yuanmu FAN ; Xuejun YU ; Xiaojun GU ; Juyi YIN ; Yajun QIU ; Shubing CHEN ; Jie CHEN ; Jia ZHAN ; Xiaoyu HE ; Jun CHEN ; Shaotang HUANG
Chinese Journal of Analytical Chemistry 2010;38(1):113-116
A method for the determination of cyromazine and dicyclanil residues on greasy wool was developed with HPLC and confirmed with HPLC-MS/MS.The cyromazine and dicyclanil residues on greasy wool were extracted with 1% trichloroacetic acid solution with ultrasonic, and cleaned up by MCX SPE column.The HPLC separation was performed on a Hypersil NH_2 using water-acetonitrile (V/V) as the mobile phase with gradient elution and detected at the wavelength of 214 nm.The corroboration method of HPLC-MS/MS was used with electro-spray ionization of positive ion mode.The [ M + H ]~+ and characteristic ions of dicyclanil were m/z 191.0, 150.0 and 163.0, and cyromazine were m/z 167.0, 85.0 and 125.0.The linear ranges of cyromazine and dicyclanil were 0.05-5.0 mg/L.There were good linear relationships between the peak area and concentration in the linear range.The correlation coefficient was 0.9999.The detection limit of cyroma zine was 0.02 mg/kg, and dicyclanil was 0.01 mg/kg.The average recoveries of cyromazine and the dicycla nil were 95.0%-99.9% and 83.6%-92.2%, respectively.