Objective To assess whether AECOPD patients can breathe independently at the PIC window and thus whether NPPV was necessary after extubation.Methods We performed a prospective observational study, we used the spontaneous breathing trial (SBT)to assess whether each patient could breathe independently at the PIC window,then performed extubation.Patients who passed the SBT received oxygen therapy only,whereas those who failed received NPPV.However,if the former showed respiratory distress,they also received NPPV.The primary out-come variables were SBT pass/fail,the demand for NPPV and rate of reintubation within 72h following extubation. Results In all,23 patients were enrolled,15cases(65.2%)of which passed the SBT.Of these,12cases (80.0%) patients developed respiratory distress after extubation and required NPPV (one of whom required reintubation).Of the eight patients that failed,one received reintubation after NPPV.The reintubation rates within 72h following extuba-tion of SBT-pass(7.0%)and SBT-fail (13.0%)(χ2 =1.476,P>0.05)patients were comparable.Conclusion Most AECOPD patients can breathe independently at the PIC window,but nonetheless develop respiratory distress and thus require NPPV following extubation.

Objective:To explore the status of early social function in young and middle-aged patients after percutaneous coronary intervention (PCI) and analyze its influencing factors, so as to provide a basis for formulating relevant intervention measures.Methods:From July to December 2021, the convenient sampling method was used to select 110 young and middle-aged patients with coronary heart disease after PCI in the First Affiliated Hospital of Harbin Medical University as the research objects. The general information questionnaire, Social Disability Screening Schedule (SDSS) , Social Support Rate Scale (SSRS) and General Self-Efficacy Scale (GSES) were used to investigate the patients. Univariate analysis and multiple linear regression analysis were used to explore the influencing factors of early social function in young and middle-aged patients with coronary heart disease after PCI. A total of 110 questionnaires were distributed and 106 valid questionnaires were recovered, with an effective recovery rate of 96.36% (106/110) .Results:The scores of SDSS, SSRS and GSES of 106 young and middle-aged patients after PCI were (3.89±1.63) , (38.80±7.02) and (21.08±6.39) , respectively. The results of univariate analysis showed that there were statistically significant differences in SDSS scores among patients with different gender, family per capita monthly income, education level and number of stents ( P<0.01) . The results of multiple linear regression analysis showed that gender, family per capita monthly income, education level, number of stents, general self-efficacy and social support were the influencing factors of early social function in young and middle-aged patients with coronary heart disease after PCI ( P<0.05) . Conclusions:The status of early social function in young and middle-aged patients with coronary heart disease after PCI is not ideal. Medical staff should give more intervention and guidance to patients after PCI who are female, have a lower education level, have a lower per capita monthly family income and have a large number of stents, consider the influence of self-efficacy and social support on the social function of patients and formulate corresponding intervention measures according to the influencing factors, so as to improve the level of social function of patients.