1.Incidence of Depression among Parkinson’s Disease in China:A Meta-Analysis
Shuqi HUANG ; Siqing LI ; Shuangyan TU
Journal of Apoplexy and Nervous Diseases 2020;37(11):984-988
Objective To analyze the rate of depression among Chinese Parkinson’s disease patients by Meta-analysis. Methods CNKI,VIP,Wanfang,PubMed,Web of Science and Embase databases were searched systematically. The studies focus on depression of Parkinson’s disease patients in China from the year of establishment to 2019 were collected. Two researchers independently screened literature,extracted data and applied the standard of Agency for Healthcare Research and Quality to evaluate the quality of literatures. According to the results of heterogeneity test,the data were analyzed by Stata 12.0 software using random effect model. Results A total of 7842 PD patients,4394 males and 3088 females,were included in 37 studies. The combined value of depression detection rate was 43.0% [95%CI (0.370,0.490)]. Subgroup analysis showed that the incidence of depression in the study with sample size<150 was 47.7% [95%CI (0.413,0.542)],and the incidence of depression in the study with sample size≥ 150 was 34.3% [95%CI (0.254,0.432)],respectively. The prevalence rates of depression with assessment tools were different,Hamilton Depression Rating for Depression 43.0%[95%CI(0.359,0.501)],Center for Epidemiologic Studies Depression Scale 38.1% [95% CI (0.301,0.461)],Self-Rating Depression Scale 41.0% [95%CI (0.163,0.657)],Beck Depression Inventory 46.0% [95%CI (0.353,0.567)]. The incidence of depression in female PD patients was 43.0% [95%CI(0.340,0.519)],43.2% [95%CI (0.330,0.533)] in male. The incidence of depression was 43.2% [(95%CI (0.330,0.533)],among patients disease duration ≤ 5 years,44.4% [(95%CI (0.362,0.501)] in patients with PD whose disease duration more than 5 years. The incidence of depression was 40.2%[95%CI(0.226,0.538)]in PD patients whose onset age ≥60 years,45.3% [95%CI(0.335,0.570)]in PD patients whose onset age <60 years. The incidence of depression was 45.4%[95%CI(0.441,0.497)]in patients with UPDRSIII score > 25,39.1%[95%CI(0.261,0.521)] in those with score ≤ 25.42.1%[95%CI(0.303,0.538)]PD patients with mild depression,22.7%[95%CI(0.160,0.293)]with moderate depression and 7.4%[95%CI(0.049,0.100)] with severe depression. Conclusion The incidence of depression is high in PD patients. The emotion of PD patients in every stage need evaluate,diagnose and cure earlier.
2.Readmission rate and related risk factors of ischemic stroke patients after 3 months of discharge in Southwest China
Lihong Zhao ; Xiaohui Miao ; Shuangyan Tu ; Muke Zhou ; Li He ; Rong Yang
Neurology Asia 2020;25(2):119-125
Background: Readmission after stroke is common, but limited data is available in West China. This
study aimed to assess the frequencies and influencing factors of unplanned readmissions within 3
months after hospital discharge. Methods: This was a retrospective study in a single center. In our
study, 596 ischemic stroke patients who were admitted to the Department of Neurology of West China
Hospital from November 2011 to August 2012 were enrolled. Demographic data, disease data and
follow–up data were collected at first admission and after 3 months of discharge. The readmission
rate and risk factors were calculated. Results: Of 596 ischemic stroke patients, the readmission
rate was 19.30% (115/596) within three-months, the top three reasons for readmission were needs
of rehabilitation (74/115, 64.35%), recurrence of stroke (14/115, 12.17%), complications (11/115,
9.57%). The readmission was associated with older age, whether patients have indwelling catheter
and endotracheal tube and pressure sores. (P < 0.05)
Conclusions: The rate of readmission within 3 months in ischemic stroke patients was 19.30%. Greater
attention should be paid to the elderly patients and patients with endotracheal tube on discharge to
reduce readmission. Extended nursing care is also needed to reduce the readmission rate of patients
with ischemic stroke.