1.Effect of damage control laparotomy on the treatment of serious pancrea injury in 38 cases
Shanyong XU ; Xuhai ZHAO ; Xiaojuan LIU ; Shuangyan WANG
Chinese Journal of Primary Medicine and Pharmacy 2009;16(5):789-790
Objective To Summarize experiences in the treatment of serious injury of pancreas using damage control laparotomy. Methods Retrospectively analyze the choice of surgical method and follow-up treatments on 38 patients cured by DCL,who were in serious injury of pancreas. Results 12 cases(32%) were stanched, surgical debrided and drainage quickly,6 cases(16%) were treated with improved Cogbill operation,and 20 cases(S3% ) were treated with pancreateduodenectomy without reconstruction of enteron. After recovery in SICU, all patients were treated with deterministic operation again. Totally 4 cases(11%) died,with no relation with surgical operation,and 34 cases (89%) were cured. Pancreatic fistula occurred in 4 patients(11% ) ,all of which have been cured with conservative treatment. Conclusion Patients with serious injury of pancreas in accordance with DCL, should choose proper method and take fractionated operation,based on different places and extent of the injury of pancreas.
2.Effect of peppermint oil on GSH and ATPase in rat liver-tissues and primary cultured rat hepatocyte
Hongjie LIU ; Ruomin JIN ; Shuangyan QI ; Caixia MEI ; Liming TANG
Chinese Traditional Patent Medicine 1992;0(05):-
AIM: To study the effect of peppermint oil on GSH、ATPase in rat liver-tissues and primary cultured rat hepatocyte. METHODS: The rat liver tissues were obtained to detect content of GSH and level of Na~+-K~+-ATPase、Ca~(2+)-Mg~(2+)-ATPase after being administered peppermint oil orally at 24 % concentration of peppermint oil in 36 and 48 hours.Primary rat hepatocyte was separated and cultured,then peppermint oil and the serum containing that were respectively added level of LDH,ALT,AST in the supernatant fluid was respectively determined after incubating for 12,24 and 48 hours. RESULTS: The content of GSH and level of Na~+-K~+-ATPase and Ca~(2+)-Mg~(2+)ATPase in liver tissues was low remarkably(P
3.Chemical constituents from Buthus martensii
Shuangyan AI ; Weiguo LI ; Yadong FENG ; Lijun TIAN ; Yuming LIU
Chinese Traditional Patent Medicine 2017;39(8):1639-1641
AIM To study the chemical constituents from Buthus martensii Karsch.METHODS The dichloromethane and 70% methanol fractions of B.martensii extract were isolated and purified by silica,ODS,Sephadex LH-20 and mid-pressure preparative column,then the structures of obtained compounds were identified by physiochemical properties and spectral data.RESULTS Nine compounds were isolated and identified as cholest4-en-3-one (1),cholesterol (2),uracil (3),1-stearyl-2-lyso-sn-glycero-3-phosphatidylcholine (4),glycerol (5),oleic acid (6),proline (7),alanine (8),leucine (9).CONCLUSION Compounds 1,4,5 are isolated from B.martensii for the first time.
4.Risk Factors for Short-term Prognosis of Transient Ischemic Attack
Na LIU ; Xuehua LI ; Shuangyan CHEN ; Yan REN
Journal of China Medical University 2010;(3):221-223,237
Objective To explore the clinical risk factors influencing the short-term prognosis of transient ischemic attack(TTA).Methods We collected the clinical data of 162 patients with TIA in this study.All the patients were followed up for 90 days.Multiple factor analysis was performed by Cox regression model(SPSS 13.0 software).Results Within 90 days after TIA,40 of 162 patients(24.7%)experienced cerebral infarction.The risk of cerebral infaition during the first 30 days after TIA was higher.The independent risk factors for the prognosis within 90 days after TIA were the duration of TIA(RR=17.172,P<0.01),hyperfibrinogenemia(RR=3.071,P<0.01),abnormal blood glucose level(RR=2.651,P<0.01),and hypertension(RR=3.356,P<0.01).Conclusion The duration of TIA,hyperfibrinogenemia,abnormal blood glucose level,and hypertension are independent risk factors for the short-term prognosis of TIA.
5.Plasma resistin level and its correlation in patients with essential hypertension of Kazakans and Han nationalities
Yinjun TIAN ; Qiangui LIU ; Zhong WANG ; Shuxia GUO ; Li ZHAO ; Jinhong LI ; Shuangyan ZHAO
Journal of Chinese Physician 2008;10(10):1342-1345
Objective To observe plasma resistin levels in patients with essential hypertension (HT) of Xinjiang Kazakans and Han nationalities, and explore its association with insulin resistance (IR), blood glucose, blood lipids, blood pressure and obesity. Methods Total 127 Kazakan cases and 131 Han cases were selected as the subjects. According to their blood pressure, they were divided into HT group of Kazakans, control group of Kazakans, HT group of Hans and control group of Hans. Blood pressure, height, weight, waist circum-ference (WC) and hip were measured. Plasma resistin, fasting insulin(FINS), fasting plasma glucose (FPG), total cholesterol (TC), tri-glyceride (TG), high-density lipoprotein cholesterol ( HDL-C), low-density lipoprotein cholesterol ( LDL-C), apoprotein-A1( Apo-A1)and apoprotein-B(Apo-B) were determined. Body mass index (BMI), waist-hip ratio ( WHR), body fat percentage ( BF% )and homeostasis model assessment of insulin resistance index ( HOMA-IR) were calculated. Results Plasma resistin levels in the HT groups of Kazakans and Hans were significantly higher than those in their control groups ( P<0.01 ). There were no significant difference in the comparison of plasma resistin levels in HT groups or control groups between Kazakans and Hans ( P>0.05). Plasma resistin was posi-tively and significandy correlated with age, systolic blood pressure (SBP), WC, BMI, WHR, BF%, FlaG, FINS, HOMA-IR, TG in HT groups of Kazakans and Hans ( HT group of Kazakans, r=0.492,0.296,0.281,0.648,0.263,0.515,0.742,0.759,0.797,0.595; HT group of Hans, r=0.417,0.275,0.391,0.483,0.278,0.318,0.453,0.560,0.641,0.310; P<0.05). After the influential factors such as age, blood glucose, blood lipids and obesity were adjusted, plasma resistin level in four groups were still positively and significantly corre-lated with FINS and HOMA-IR ( HT group of Kazakans, r=0.432,0.410 ; control group of Kazakans, r=0.327,0.305 ; HT group of Hans, r=0.426,0.425 ; control group of Hans, r=0.377,0.392 ; P<0.05), but not correlated with SBP or DBP( P>0.05 ). HOMA-IR, FPG and BMI were independent factors for plasma resistin level in HT group of Kazakans, while HOMA-IR, FlaG and BF% were inde-pendent factors for plasma resistin level in HT group of Hans. Conclusion Plasma resistin level was increased in patients with HT of Kaza-karts and Hans. Close correlations between resistin and obesity, blood glucose and IR were found, and there may be indirect correlation be-tween resistin and blood pressure.
6.A case of nasal NK/T-cell lymphoma
Yi ZHAN ; Guangcheng ZHANG ; Jian LIU ; Shuangyan LUO ; Qianjin LU ; Rong XIAO ; Guiying ZHANG
Journal of Central South University(Medical Sciences) 2017;42(7):860-864
A 29-year-old male patient with extranodal NK/T-cell lymphoma,a nasal type lymphoma with involvement of skin as the first symptom,was reported.The patient presented with swelling in the left side of the nose and suffered intermittent fever for 1 month.The fester in the oral mucosa and skin under the left nostril and redness,and the swelling on the orbit of the left eye lasted for 1 week.Physical examination showed that the left side of nose was swelling,and the skin below the left nostril was anabrotic and crusted.There were different ulcers in his jaws and buccal mucosa.Bilateral eyelid was redness and swelling,especially in the left side.Binocular conjunctival was congestive.The diagnosis of extranodal NK/T-cell lymphoma (nasal type) was confirmed by biopsy and immunohistochemistry.
7.Clinical observation of formula for clearing heat,eliminating phlegm and relaxing bowel on treating encephalopathy complicated with pulmonary infection
Junying LV ; Kai LI ; Liping HUANG ; Aize XIE ; Xuejia ZHENG ; Juan LIANG ; Shuangyan LIU
The Journal of Practical Medicine 2017;33(6):1001-1004
Objective The efficacy and safety of rectal instillation with formula for clearing heat, eliminating phlegm and relaxing bowel on treating encephalopathy complicated with pulmonary infection were evaluated by randomized controlled clinical trials. Methods Eighty eligible cases of encephalopathy complicated with pulmonary infection were randomly divided into treatment group and control group. Control group was given conventional treatment and treatment group was given rectal instillation treatment with formula for clearing heat , eliminating phlegm and relaxing bowel. The changes of index were observed before and after treatment in two groups including temperature,antifebrile time,white blood cell count,neutrophils ratio,C-reactive protein,procalcitonin, pneumonia severity index,and the efficacy score of TCM syndrome. Results Rectal instillation with formula for clearing heat and eliminating phlegm to relax bowel can be better improved encephalopathy complicated with pulmonary infection with syndrome of phlegm-heat obstructing in which the patients have yellow sputum, constipation,yellow urinary and other symptoms. It can reduce TCM syndrome score and level of serum calcitonin, relieve inflammation,enhanc antibacterial effect,and improve the clinical curative effect. Conclusions The curative effects of rectal instillation with formula for clearing heat and eliminating phlegm to relax bowel on treating encephalopathy complicated with pulmonary is definite which has no adverse reaction and safety use. It is worthy of further popularizing in clinic.
8.Effect of Multidisciplinary Comprehensive Pulmonary Rehabilitation on Aged Patients with Pneumoconiosis
Yinjun TIAN ; Qiangui LIU ; Jinhong LI ; Lili ZHAO ; Shuangyan ZHAO ; Miaozi ZHOU ; Yuan ZHANG ; Xuehong MA
Chinese Journal of Rehabilitation Theory and Practice 2017;23(3):352-357
Objective To explore the effects of multidisciplinary comprehensive pulmonary rehabilitation on aged patients with pneumo-coniosis. Methods From January, 2012 to January, 2015, 85 old stable inpatients with pneumoconiosis were divided into control group (n=40) and rehabilitation group (n=45). Both groups accepted routine medicine, while the rehabilitation group received multidisciplinary com-prehensive pulmonary rehabilitation for twelve weeks. They were assessed with cardiopulmonary exercise test, BODE index and quality of life before and after treatment. Results The maximum work, maximal oxygen uptake, 6-minute walk distance, scores of modified Version of the British Medical Researsh Council Respiratory Questionnaire, BODE index, activities of daily living, social activities, depression and anx-iety improved in the rehabilitation group after treatment (t>3.379, P<0.01), and were better than those in the control group (t>2.201, P<0.05). No imporvement was found in all the indices in the control group after treatment (t<2.339, P>0.05). Conclusion Multidisciplinary comprehensive pulmonary rehabilitation can effectively improve exercise tolerance and quality of life in aged patients with pneumoconiosis.
9.The Quadriplegia Index of Function in Use wiith Quadriplegic Patients:A Preliminary Report
Jiazong WANG ; Hongjun ZHOU ; Genlin LIU ; Yuhua MA ; Yufen CHEN ; Xuemei WU ; Xuemei LIU ; Shuangyan HU ; Aimin ZHANG
Chinese Journal of Rehabilitation Theory and Practice 1995;1995(1):10-12
Presented in this paper is a report on the Quadriplegia Index of Function(QIF) in usewith 16 cases of quadriplegic patients.Compared with the Barthel Index and Japan ADL Scale,QIF wasfound to be more sensitive and effective to document the small but significant funtional gains made byquadriplegics during medical rehabilitation,therefore,authors suggest that QIF should be widely usedin the rehabilitation evaluation of quadriplegic patients.
10.Effects of grading pulmonary rehabilitation nursing on weaning trend among patients with mechanical ventilation in intensive care unit
Chinese Journal of Practical Nursing 2022;38(11):807-811
Objective:To explore the effects of grading pulmonary rehabilitation nursing on weaning trend among patients with mechanical ventilation in ICU.Methods:A total of 68 patients with mechanical ventilation from May 2018 to May 2019 in ICU of Guangzhou Red Cross Hospital were divided into the experimental group and the control group with 34 cases in each group by random digits table method. The control group was given routine rehabilitation nursing and the experimental group was given graded pulmonary rehabilitation nursing based on routine nursing. The differences between the two groups were compared in terms of rapid shallow breathing index(RSBI), oxygenation index, mechanical ventilation time, hospitalization time, success rate of weaning and incidence of complications.Results:On the 5th day and the 7th day after the intervention, the RSBI were 80.59 ± 5.69 and 75.74 ± 8.62 in the experimental group, which were significantly lower than those in the control group (89.54 ± 8.96 and 85.15 ± 9.75), ( t=5.06 and 4.28, both P<0.05). On the 3th, 5th, 7th day after the intervention, the oxygenation index were (244.82 ± 22.77), (248.21 ± 17.49) and (263.79 ± 17.31) mmHg in the experimental group, which were significantly lower than those in the control group (137.41 ± 15.01), (192.79 ± 15.82) and (206.26 ± 17.40) mmHg, ( t=22.97, 13.70, 13.67, all P<0.05). The duration of mechanical ventilation, length of ICU stay and the incidence of ventilator-associated pneumonia, deep venous thrombosis were (11.29 ± 1.38) days, (12.47 ± 1.73) days and 0, 0 in the experimental group, which were significantly lower than those in the control group (12.18 ± 1.47) days, (13.53 ± 1.62) days and 11.8%(4/34), 14.7%(5/34). The withdrawal success rate was 94.1%(32/34) in the experimental group, significantly higher than that in the control group 76.5% (26/34), the difference was statistically significant ( χ2=4.22, P<0.05). Conclusions:Grading pulmonary rehabilitation nursing can improve the respiratory function, shorten the time of mechanical ventilation and the length of ICU hospitalization, as well as reduce the occurrence of complicaitons.