Objective To explore the influence of minimally invasive percutaneous plate psteosynthesis on the postoperative healing and functional recovery of patients with comminuted fracture of proximal end of humerus.Methods Clinical materials of 58 patients with comminuted fracture of proximal end of humerus were analyzed.Results Incision of 58 cases were stage Ⅰheal,the average length of hospital stay was (16.35±2.71)days,fracture healed completely in 55 cases,the average healing time was (13.53±2.64)weeks.3 patients′X-rays showed there was no callus growth.According to Neer scores (100 point scale),the average score of function recov-ery was (85.44±10.95).Different fracture fractal function recovery time and the comparison of type II patients with type Ⅲ had no obvious difference (P <0.05).Conclusion MIPPO has a quite good cure effect on the patient with comminuted fracture of proximal end of humerus.For type Ⅱ and type Ⅲ fracture patients,the efficacy was obviously better than that of type Ⅳ pa-tients.

Objective To explore the influence of minimally invasive percutaneous plate psteosynthesis on the postoperative healing and functional recovery of patients with comminuted fracture of proximal end of humerus.Methods Clinical materials of 58 patients with comminuted fracture of proximal end of humerus were analyzed.Results Incision of 58 cases were stage Ⅰheal,the average length of hospital stay was (16.35±2.71)days,fracture healed completely in 55 cases,the average healing time was (13.53±2.64)weeks.3 patients′X-rays showed there was no callus growth.According to Neer scores (100 point scale),the average score of function recov-ery was (85.44±10.95).Different fracture fractal function recovery time and the comparison of type II patients with type Ⅲ had no obvious difference (P <0.05).Conclusion MIPPO has a quite good cure effect on the patient with comminuted fracture of proximal end of humerus.For type Ⅱ and type Ⅲ fracture patients,the efficacy was obviously better than that of type Ⅳ pa-tients.

Objective To discuss the application of nano-hydroapatic crystals and polyamide composite(n-HA/PA66) for artificial vertebrae in treating thoracic or lumbar vertebrae tumor.Methods A total of 14 cases suffering from thoracic or lumbar vertebrae tumor underwent deuto-total vertebrae resection via anterior approach,then canalis vertebralis was deboosted,artificial vertebrae was implanted and fixed with screw-stick system.Fourteen patients,9 male and 5 female were admitted by our hospital from Dec 2003 to Sep 2005,aged 32 to 68 years old(average 50).The tumor located at T_(11) in 2 cases,T_(12) in 2,L_1 in 5,L_2 in 5.Pathological diagnosis showed 3 cases were of aneurysmal bone cyst,5 of hemangioma,2 of giant cell tumor,3 of metastatic thoracic lumbar vertebra tumor. Results The follow-up lasted 3-18 months,mean 10 months.The rate of bone graft fusion reached 85.7%,with no loosened internal fixation or breakage of screw or stick.No screw breakage or spinal instability occurred during the follow-up.All cases were alive till follow-up finished.Conclusion If the thoracic vertebral tumor compresses spinal cord seriously,the patients should be recommended for surgical treatment.Total vertebrectomy followed by reconstruction could relieve the compression caused by tumor and restore the stabilization of spine effectively.Artificial vertebrae is the ideal substitute material for bone transplantation,for it has good biocompatibility,high security,high rate of bone graft fusion and firm fixation.

Objective To analyze the characteristics of clinical manifestations, risk factors, therapies and acute outcomes in patients with cerebral venous sinus thrombosis complicated by cerebral hemorrhage. Methods Seventy-five patients with cerebral venous sinus thrombosis were included in the study. According to the radiological findings on the brain image, patients were divided into two subgroups:cerebral hemorrhage group and non-hemorrhage group. The demo?graphic data, potential risk factors, clinical manifestations, radiological features, therapeutic strategies and acute out?comes were compared between two subgroups, and high risk factors were also analyzed. Results There were seventy-five patients with cerebral venous sinus thrombosis in the present study. Twenty-eight patients of them (37.2%) had cerebral hemorrhage whereas the remaining forty-seven patients (62.7%) did not have cerebral hemorrhage. Pregnancy/puerperi?um were significantly higher in patients with cerebral hemorrhage (with vs without;28.6%vs. 6.4%, P=0.015), while in?fection was markedly higher in patients without cerebral hemorrhage (with vs without;7.1% vs. 29.8%, P=0.021). Head?ache (92.9% vs. 70.2%, P=0.021), unconsciousness (25.0% vs. 6.4%,P=0.034), seizures (53.6% vs. 19.1%, P=0.002) and motor deficits (35.7% vs. 12.8%, P=0.019) were more common in patients with cerebral hemorrhage. Moreover, mul?tiple sinus involvement (1.4% vs. 44.7%, P=0.024) was significantly higher and the acute outcomes(mRS≥3: 46.4%vs.17.0%, P=0.006)were poorer in patients with cerebral hemorrhage. Binary Logistic analysis showed that pregnancy/pu?erperium (P=0.004) and multiple sinus involvement were positively, whereas infection was negatively correlated with cere?bral venous sinus thrombosis and hemorrhage ( P=0.007;P=0.03). Conclusions Pregnancy/puerperium, headache, uncon?sciousness, seizures, motor deficits and multiple sinus involvement are more frequently in patients with cerebral venous sinus thrombosis and hemorrhage, and the acute outcomes are poorer in patients with cerebral venous sinus thrombosis complicated by cerebral hemorrhage.