Retinopathy of prematurity(ROP) has evoken generally social attention now,and correlated reports point that prematurity and low birth weight could be the foundation of ROP,and irrationable oxygen therapy could be the significantly causative factor for some premature infants with shorter gestational age,maldevelopment and low birth weight.The irrationable oxygen therapy includes aspiration of hyperxia,long-time aspiration of oxygen and striking fluctuation of oxygen partial pressure.The review would summarize the relationship between retinopathy of prematurity and oxygen therapy according to lately research reports,and search for the certain cause,pathogenesy and the method of prevention and cure of ROP.

Neonatal necrotizing enterocolitis (NEC) is the most common neonatal gastrointestinal disease and has most lethal effect. In recent years,with the development of the neonatal intensive care unit,the survival rate of premature infants is increased, but the incidence rate of NEC is also increasing. At the present stage,the etiology of NEC is still not completely clear,which greatly limits the prevention and treatment of NEC. Risk factors including premature birth, infection, bacterial colonization, hypoxia ischemia,inflammatory reaction and enteral nutrition are summarized in this paper to provide basis for clinical diagnosis,treatment and prevention of NEC.