ObjectiveTo investigate the clinical effect of Chinese Medicine Naotan Ⅰ on cerebral palsy. Methods120 orphans with cerebral palsy from welfare houses were divided into experimental group and control group. The former took Naotan Ⅰ and the latter took piracetam. ResultsThe total effective rate was 93.33% in the experimental group and 78.67% in the control group (P<0.05).ConclusionNaotan Ⅰ is effective on cerebral palsy of children.