Objective To compare the analgesia effect and the safety of Flurbiprofen Axetil (FA) and Parecoxib Sodium (PS) after posterior lumbar fusion surgery. Methods 90 patients undergoing internal fixation of lumbar spine randomly assigned to 3 groups:those in Group A(n = 30) received 100 mg of FA; those in Group B (n=30) received 40 mg of PS and those in Group C received saline.The VAS scores of 2, 6, 12, 24, 48, 72 h after operation and the dose of tramadol hydrochloride (TH) used and the side effect was recorded respectively. Results Group A and B had significantly better analgesic effect than Group C(P<0.05). Group A and B had lower average dose of TH than Group C (P<0.05). The VAS scores in Group A was lower than that in Group B in 2 h after the surgery. The VAS scores after the surgery showed no significant difference between Group A and B in 6 , 12, 24 h after the surgery. The VAS scores in Group A was higer than that in Group B in 48,72 h after the surgery. Conclusion Both PS and FA can alleviate postoperative pain and have fewer adverse reactions.

BACKGROUND:Closed reduction using proximal femoral nail antirotation gradual y becomes the golden standard in the treatment of intertrochanteric fractures.
OBJECTIVE:To evaluate the advantages of proximal femoral nail antirotation in the treatment of intertrochanteric fractures by a new way that accurate positioning is used to modify the skin incision.
METHODS:Ninety-nine patients with intertrochanteric fractures undergoing proximal femoral nail antirotation were included in the study, including 41 cases in the modified incision group and 58 cases in the standard operation group. Length of skin incision, mean bleeding volume, mean operation time, mean hospitalization time and the Harris scores were compared between two groups postoperatively.
RESULTS AND CONCLUSION:Compared with the standard incision group, the mean bleeding volume and length of skin incision were decreased by 50.9%and 44%respectively in the modified incision group, as wel as the mean operation time was also shorter in the modified incision group (P<0.05). However, there was no difference in mean hospitalization time and Harris scores at the end of fol ow-up. The modified incision is more suitable for proximal femoral nail antirotation treatment of intertrochanteric fractures, with smal er incision, less trauma, shorter operation time and less blood loss.

Objective To explore the efficacy of early aggressive debridement with implant retention, primary wound clo-sure, closed suction drain without irrigation and antibiotic therapy for the treatment of delayed deep infection after spinal fixation. Methods 4057 patients were underwent dorsal spinal fixation from January 2010 to June 2014. Among them, 42 cases of de-layed deep infection after operation were included in the study. There were 25 males and 17 females, with an average age of 68.6± 8.1 years (ranged from 53 to 83 years). The diagnosis of delayed deep infection was based on the time of onset, clinical symptoms and signs, imaging and laboratory findings. Surgical debridement was performed immediately after diagnosis of infection. In addi-tion, devitalized and necrotic tissue and biofilms which adhered to the surface of the implant were removed meticulously and thor-oughly. Primary wound closure was performed in each patient, and closed suction drains were maintained for about 7-10 d without irrigation. Routine sensitive antimicrobial drugs was applied for 3 months after operation. Results 42 cases were all followed up for 24 to 72 months with an average of 46 months. Among the 42 infected patients, 3 patients were underwent posterior cervical spine surgery and 39 patients were underwent posterior lumbar spine surgery. There were 13 cases of staphylococcus aureus infec-tion, 7 cases of escherichia coli infection, 3 cases of ESBL escherichia coli infection, 3 cases of enterobacter cloacae infection, 2 cases of MRSA, 2 cases of acinetobacter baumannii infection, 2 cases of klebsiella pneumoniae infection, 1 case in enterococcus faecium and pseudomonas aeruginosa and staphylococcus haemolyticus, respectively. There were still 7 patients with negative bacterial culture. 41 cases retained their implant, whereas 1 staphylococcus aureus infection patient had the implants removed be-cause of loosening during debridement. Nevertheless, primary wound healing was found in all patients, and stitches were removed 2 to 3 weeks after debridement. Infections were effectively controlled with no recurrence of infection during the follow-up. The av-erage erythrocyte sedimentation rate was (65.76±20.08) mm/h preoperative, (41.43±14.65) mm/h 1 month postoperative, (10.81±2.72) mm/h 6 months postoperative, and (8.10±5.46) mm/h 12 months postoperative, respectively, the differences were statistically significant. The average C reactive protein was (40.55±16.91) mg/L preoperative, (6.50±2.46) mg/L 1 month postoperative, (4.31± 1.26) mg/L 6 months postoperative, and (3.83±1.50) mg/L 12 months postoperative, respectively, the differences were statistically significant. The average procalcitonin was (0.47±0.28) ng/ml preoperative, (0.08±0.06) ng/ml 1 month postoperative, (0.06±0.03) ng/ml 6 months postoperative, and (0.05±0.00) ng/ml 12 months postoperative, respectively, and the differences were statistically significant. Conclusion A timely diagnosis, aggressive and meticulous debridement, high vacuum closed-suction drain, routine and adequate use of antibacterial agents are keys to successfully resolving infection and maintaining implant retention in the treat-ment of delayed deep infection after spinal fixation.

Objective To observe the clinical efficacy of modified laminoplasty with C3 laminectomy and C7 spinous process retention in the treatment of cervical ossification of the posterior longitudinal ligament(OPLL).Methods From February 2014 to March 2016,133 cases of OPLL were admitted,and 42 OPLLs were included according to the inclusion and exclusion criteria.A case-control study was conducted.Twenty-two cases were included in modified group and 20 cases in traditional group.There were 13 males and 9 females in the modified surgery group,and the average age was 56.2±9.75 years (39-77 years).Modified surgery was conducted with C3 laminectomy,C4-C6 laminoplasty,resection at the upper part of the C7 lamina and retaining the C7 spinous process.Meanwhile,there were 12 males and 8 females in the traditional surgery group,with an average age of 53.7± 8.23 years (41-75 years).Patients in the traditional surgery group were treated with standard C3-C7 laminoplasty.The mean followup was 22.9±4.5 (15-29) months.The JOA,NDI scores of the two groups were recorded preoperatively and postoperatively.The physiological curvature and activity of the cervical spine before and after operation were observed,and the incidence of axonal symptoms and postoperative complications in both groups were recorded.Results The follow-up period was 15-28 months,with an average of (23.2 ± 4.8) months.There was no significant difference between the base line of two groups before operation.At the last follow-up,the JOA and NDI scores of the two groups were significantly improved.There was no difference of JOA scores between the two groups at the last follow-up,while the NDI sores at the modified group(6.56±4.78) was superior to the traditional group(9.25±7.63).The VAS score at the first day after surgery in modified group was lower than that of the traditional group.The average cervical curvature of the patients in the modified surgery group and the standard surgery group were 12.32°±8.26° and 11.56°± 8.05°,respectively.There was no significant difference between the two groups.The postoperative range of movement (ROM) of cervical spine was 39.68°±9.52° in modified group and 33.51°± 10.39° in traditional group(P＜0.05).Eight patients (19％) had augmentation of axial symptoms,including 3 patients in the modified surgery group(13.6％) and 5 patients in the standard surgery group (30％).There was no significant difference between the two groups.During the follow-up period,there were no complications such as cerebrospinal fluid leakage,spinal cord injury,wound infection,laminar collapse,postoperative closure,internal fixation loss or fracture.Conclusion The modified laminectomy with C3 laminectomy and C7 spinous process retentionis minimally invasive,whichachieved satisfactory decompression effect,reduced the incidence of postoperative axial symptoms and maintained the cervical ROM.

Objective:A clinical case of rotational vertebral artery occlusion (bow hunter's syndrome, BHS) caused by left C 1 osteophyte was reported, and the epidemiological characteristics, diagnosis and treatment methods, and clinical outcomes of BHS were further analyzed. Methods:The clinical data, diagnostic methods, treatment options, and clinical outcomes of the above-mentioned BHS patient are described. The literature from 1978 to 2021 was retrieved, the BHS patients involved were taken as the research objects, and the data of onset age, gender, etiology, site of onset, diagnosis method, treatment method, and clinical outcomes of each selected patient were collected. The data were subdivided through systematic analysis.Results:A patient with rotational compression of the left vertebral artery associated with the left osteophyte of the atlas was presented. 3D-CT showed that the vertebral artery was compressed by the left osteophyte of the atlas. Dynamic digital subtraction angiography (dDSA) showed mild stenosis of the distal V2 segment of the left vertebral artery. When his head turned to the left, the distal V2 segment of the left vertebral artery was compressed and the blood flow was interrupted. After his head was in a neutral position, the blood flow was restored. Because the symptoms could not be relieved after conservative treatment, posterior C 1 osteophyte resection was used to decompress the vertebral artery, and the symptoms disappeared after the operation, and the short-term follow-up results were good. All of the 87 articles and 126 patients have been studied. The median age was 55.0 years (IQR: 43.5, 65.0 years) and the peak age of onset was 51 to 60 years old. The gender difference has been uncovered and the sex ratio was 1.9∶1 (male∶female). Among the 126 patients, 65 patients had vertebral artery occlusion or stenosis located in the C 1-C 2 segment; 66 patients involved the left vertebral artery, 45 patients involved the right vertebral artery, and 15 patients involved bilateral vertebral arteries. DSA was used to confirm BHS in 114 of 126 patients. The follow-up time was 0.25-114 months, with an average of 16.6 months. Thirty-six patients were treated conservatively, and 12 patients had residual symptoms; 33 patients underwent fusion surgery, and all patients' symptoms were relieved after surgery; 54 patients underwent simple decompression surgery, and 4 patients had residual symptoms after surgery; 4 patients received endovascular surgery, and their symptoms were relieved after surgery. Conclusion:Patients with BHS are rare clinically, often involving C 1-C 2 and the left vertebral artery is more likely to be involved. The peak age of onset was 51 to 60 years old. DSA is the gold standard for the diagnosis of BHS. For BHS caused by abnormal bone structure, intervertebral disc herniation, joint instability, etc., decompressive surgery of the vertebral artery or C 1-C 2 segment fusion is the most common treatment modality.