Objective: To explore the predictors of the non-survivable patients with severe cerebral infarction after mechanical ventilation. Methods: The clinical data of 36 patients with acute cerebral infarction who had tracheal intubation were analyzed retrospectively. The patients were divided into survivor (n = 18) group and non-survivor group (n = 18) according to their prognosis. The observational endpoint was at day 60. Patients' Glasgow Coma Scale (GCS) score, respiratory function (blood gas pH value, oxygen partial pressure, carbon dioxide partial pressure, and oxygenation index), and the causes of death before tracheal intubation were documented. Results: The mortality at day 60 after mechanical ventilation was 50% in patients with severe cerebral infarction. The median GCS score was 3. 6 ± 1. 0 in the non-survivor group, and the median GCS score was 6.3 ± 1.2 in the survivor group before tracheal intubation. Oxygen partial pressure and oxygenation index presented to decrease in both groups before the tracheal intubation. The median oxygen partial pressure in the survivor and non-survivor groups were 69 ± 17 and 52 ± 7 mm Hg, respectively; and the oxygenation indexes were 170 ± 31 and 109 ± 34, respectively. The univariate analysis showed that the patients' GCS scores decreased before the tracheal intubation. The decrease of oxygen partial pressure and oxygenation index were the important factors for predicting mortality. The multivariate regression analysis showed that the patients' GCS score (P = 0.015) and oxygen partial pressure (P = 0.026) before the tracheal intubation were an independent factors for predicting the mortality in patients with cerebral infarction at day 60 after the mechanical ventilation. Conclusion: For patients with severe cerebral infarction, the mechanical ventilation support may contribute to decreasing the mortality, particularly in patients whose respiratory system complications have resulted in deterioration of the disease. The aggregate analysis has showed that the patients' severity of conscious disturbance and the oxygenation parameters before the tracheal intubation may contribute to predicting the prognosis.

Animals ; Herpesviridae ; genetics ; metabolism ; Herpesviridae Infections ; virology ; Humans ; Viral Envelope Proteins ; genetics ; metabolism

Bronchogenic Cyst ; diagnosis ; Diagnostic Errors ; Goiter ; Goiter, Nodular ; diagnosis ; Humans ; Neck

Carcinoma, Adenoid Cystic ; diagnosis ; surgery ; Endoscopy ; Humans ; Neoplasm Recurrence, Local ; diagnosis ; Nose ; surgery ; Nose Neoplasms ; diagnosis

Objective To explore the application of question-based lectures made by students in teaching chapter of nuclear chemical and biological weapon damage among field military nursing.Methods The participants were junior students of four-year undergraduate program.Questions on emergency treatment and care of chemical and biological weapon damage were proposed after a lecture by teacher.Students were divided into three groups after class and each group was assigned to a lecture on emergency treatment and care of one kind of weapon damage.Students had to collect information and prepare PPT for the next lecture.After lectures given by students at next class,discussion on the lectures was organized and comments were given by teachers.Results All students approved this kind of teaching activities,97.44％ believed that it can arouse their interest in study,94.87％ participated in the collection of data,89.74％ took part in the discussion,and 87.18％ obtained the sense of achievements.Conclusion Question-based lectures made by students are helpful in stimulating their interest in learning,cultivating their abilities of acquiring and applying knowledge.The teaching activities achieve the preferable results through proper application and meticulous organization.

Objective To detect Tp-e/QT ratio in patients with acute ST-segment elevation myocardial infarction (STEMI) and explore its clinical significance. Methods Healthy individuals and patients with acute STEMI were recruited in this study. Their first QTc,QTd and Tp-e were measured within 24 h after admission to hospital,and Tp-e/QT ratio was calculated so as to analyze the relation between Tp-Te/QT ratio and malignant ventricular arrhythmia. Results Compared with those of the healthy individuals,the intervals of QTd,Tp-e and QTc were significantly lengthened \[(33.66?16.76)ms vs. (55.29?31.12)ms,(89.55?12.61)ms vs. (142.65?39.33)ms,and (426.57?65.03)ms vs. (482.26?48.03)ms,P