Colorectal Neoplasms ; diagnosis ; prevention & control ; Humans ; Translational Medical Research

Central nervous system demyelination in children include acute disseminated encephalomyelitis (ADEM),multiple sclerosis (MS),optic neuritis(ON),transverse myelitis(TM),neuromyelitis optica(NMO).Most of these conditions are thought to be caused by immune -mediated demyelination triggered by an infectious agent in a ge-netically susceptible host.There are certain differences,including clinical features and imaging features,for these condi-tions.With the possible exception of the NMO -IgG autoantibody found in NMO,there are no disease -specific biomar-kers for these conditions,making it difficult to distinguish among them at the time of the initial presentation.However, certain clinical features,laboratory results,and imaging findings can usually lead to the correct diagnosis.MS is to a large extent still a diagnosis of exclusion,and therefore requires intense investigation for other conditions that might present in a similar manner.

The modern education requires creativity while the key to foster creativity is divergent thinking.To foster divergent thinking,we should reform the education system,improve the method,and change the evaluation method.Thus we can help students form comprehensive thinking capacity,shape question consciousness,get rid of conventionalism thinking type,foster divergent thinking,and improve the comprehensive quality.

Objective To evaluate the safety of epidural resiting and the incidence of postdural puncture headache following accidental dural puncture. HZ Methods Among 63 patients of ASA I-II undergoing lower abdominal or lower extremity surgery, forty-two with postdural puncture who had received epidural resiting were randomly assigned to patient controlled epidural analgesia (PCEA) ( n =21) or control treatment ( n =21). The remaining 21 patients who had successful epidural insertion received the routine PCEA. All patients after operation received 48-hours monitoring of BP, HR, RR and SpO_2. The analgesic effect of each treatment and the occurrence of headache were also assessed. Results All operations were uneventful under epidural anesthesia. A satisfactory level of analgesia was observed in patients who received PCEA. There was no statistically significant difference in pain control between patients who had had epidural resiting and who received PCEA and those who received routine PCEA. No respiratory inhibition was observed. The occurrence of headache in the epidural resiting group was 19% (4/21), compared to 57% (12/21) in the control group ( P

It is reported in this article that the effect of Jie Mei Traditional Chinese Herbal Medica- ment for Women's Health Care on Hemorheology in experimental rats. The result suggested that the compound medicament had an evident action on antichrombosis.

Objective:To screen auramine O in Guci tablets. Methods:Auramine O was detected by HPLC method on a Diamon-sil-C18(250mm×4.6mm,5μm)columnwiththemobilephaseofacetonitrile-0.025mol·L-1monopotassiumphosphatebuffersolu-tion(containing 0. 2% triethylamine,adjusting pH to 3. 0 with phosphoric acid)(36∶65)at the flow rate of 0. 8 ml·min-1. The detec-tion wavelength was 432 nm and the column temperature was 35℃. Results:The LOD of auramine O was 0. 05ng. Among 45 batches of tested samples, auramine O was found in seven ones. Conclusion:The method is simple, rapid and accurate, which can guarantee the drug safety of Guci tablets.

Intracranial pressure monitoring is a mainstay in the management of children with severe traumatic brain injury.The research issues on the intracranial pressure monitoring have become important for neurocritical care.This paper has reviewed the significance of intracranial pressure monitoring in children with severe traumatic brain injury.

Objective To explore the value of hepcidin measurement in differential diagnosis of iron deficiency anemia(IDA) and anemia of chronic diseases(ACD) .Methods Serum hepcidin was measured by using ELISA .Serum iron(SI) and total iron binding capacity(TIBC) were determined by using Ferro zine colorimetric method .Results Hepcidin expression increased in ACD group (P<0 .05) ,but decreased in IDA group(P<0 .05) .The area under the curve of ROC for hepcidin ,SI and TIBC were 0 .97 ,0 .66 and 0 .85 respectively .Conclusion Hepcidin is a simple and safe indicator in differential diagnosis of IDA and ACD ,and its diagnos-tic accuracy is better than SI and TIBC .

BACKGROUND:There is no unified conclusion on the efficacy of immediate implantation and restoration. Some studies have shown that the success rate and aesthetic effect of immediate implantation are better than those of delayed implantation. However, in other studies, the immediate implantation has no difference from the delayed implantation, and it also has safety hazards. OBJECTIVE:To observe the clinical efficacy and safety of BLB implant for immediate implantation and delayed implantation. METHODS:Eighty patients undergoing denture implantation and restoration, 35 males and 45 females, aged 20-52 years were equaly divided into research group treated with immediate implantation of BLB implant and control group treated with delayed implantation. Crown restoration was completed at 3 months after implantation. Then, the patients were folowed up for 6 months to observe the implant stability, implantation efficacy and adverse effects. RESULTS AND CONCLUSION:There was no intra-group or intergroup difference in the implant stability quotients of two groups at 1, 3, 6 months after restoration (P> 0.05). The total effective rate was 95% in the research group and 90% in the control group, and there was no significant difference between the two groups (P > 0.05). In the research group, there was one case of gingivitis and one case of lower lip numbness; in the control group, there were two cases of wound infection and one case of lower lip numbness, but there was no difference in the incidence of complications between the two groups (P > 0.05). These findings indicate that BLB implant has good efficacy and safety both in immediate implantation and delayed implantation.