1.Effects of scallop skirt glycosaminoglycan on the expression of c-myc and TNF-? genes in proliferative vascular smooth muscle cells
Liying SHA ; Ying YANG ; Yi YIN ; Shouyi DING
Chinese Journal of Marine Drugs 2001;0(05):-
Objective To observe the effects of Chlamys farreri skirt glycosaminoglycan(SS-GAG) on the expressions of c-myc and TNF-? genes so as to explore the anti-atherosclerosis(AS) mechanism of SS-GAG.Methods The cell proliferation model of vascular smooth muscle cells(VSMC) was established by basic fibroblast growth factor(bFGF) induction.In Situ hybridization marked by non-isotope was applied to determine the effects of SS-GAG on the mRNA levels of c-myc and TNF in proliferative VSMC.Results The mRNA levels of c-myc and TNF in low dose group and high group of SS-GAG were obviously lower than that of model group(P
2.Estrogen-like effects of saikosaponin-d in mice.
Yong LI ; Peng WANG ; Jianlin REN ; Dongying YUAN ; Shouyi YIN
Journal of Integrative Medicine 2009;7(7):657-60
To investigate whether saikosaponin-d (SSd) had estrogen-like effects in mice.
Result Analysis
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