1.Methods of removing the baseline wander in ECG based on the lifting wavelet transform
China Medical Equipment 2014;(3):16-19
Objective:To avoid the redundant computation based on the convolution operation in the traditional wavelet transform, and to remove the baseline wander noise existing in the course of collecting the ECG signal. Methods: Use the lifting wavelet transform with two wavelets, and constitute the ECG signal with the noise removed after decomposing, setting the subband coefficient including the noise to zero, and rebuilding. Results:Use MATLAB to remove the baseline wander noise in the ECG signal and bw provided by the MIT-BIH database, and the results show that the baseline wander was removed effectively. Conclusion:The baseline wander noise in the ECG signal can be removed accurately though the method mentioned above, the waveform information in the original ECG signal can be maintained effectively, and subsequently, that can provide help for detecting the characteristic parameters in the ECG signal.
2.Expressions of epidermal growth factor receptor signaling substances in gastric mucosal cells influenced by serum derived from rats treated with electroacupuncture at stomach meridian acupoints
Jie YAN ; Zongbao YANG ; Xiaorong CHANG ; Shouxiang YI ; Yaping LIN ; Yan ZHONG
Journal of Integrative Medicine 2007;5(3):338-42
OBJECTIVE: To study the effects of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expressions of epidermal growth factor receptor (EGFR) signaling substances phospholipase C gamma-1 (PLC gamma-1), protein kinase C (PKC) and c-myc in gastric mucosal cells. METHODS: Sixty rats were randomly divided into normal group, stomach meridian group, gallbladder meridian group, stomach meridian plus PD153035 group and gallbladder meridian plus PD153035 group. Water-immersion and restrained stress methods were adopted for inducing gastric mucosal injury in the rats. Gastric mucosal cells were separated by using pronase digestion method, and incubated by PD153035, a EGFR inhibitor, and 100 ml/L serum. The expression of PLC gamma-1 in the gastric mucosal cells was tested by enzyme linked-immunosorbent assay (ELISA), while the expression of PKC by isotope incorporate assay and the expression of c-myc by reverse transcription polymerase chain reaction assay (RT-PCR). RESULTS: In gastric mucosal cells, weak expressions of PLC gamma-1, PKC and c-myc were seen in the normal group, and relatively strong expressions of PLC gamma-1, PKC and c-myc were seen in the stomach meridian group and the gallbladder meridian group, among which, the expressions of PLC gamma-1, PKC and c-myc in the stomach meridian group were the strongest, and there was a significant difference between the stomach meridian group and the gallbladder meridian group (P<0.01). Relative weak expressions of PLC gamma-1, PKC and c-myc were seen in the stomach meridian plus PD153035 group and the gallbladder meridian plus PD153035 group, and there was a significant difference between the stomach meridian group and the stomach meridian plus PD153035 group (P<0.01). CONCLUSIONS: The serum derived from the rats treated with electroacupuncture at stomach meridian acupoints can activate the EGFR singling pathway, and this provides an evidence for the theory of "relative particularity between meridians and viscera" in traditional Chinese medicine.