Objective To explore the common pathogenic bacteria and medication in urinary tract infection in the patients with spinal cord injury (SCI). Methods 240 SCI patients were analyzed retrospectively in China Rehabilitation Research Center from January 2009 to October 2010, who were diagnosed as urinary tract infection (UTIs) according to urine culture and bacterial identification. Results The first 3 positions of pathogenic bacteria were Gram-negative bacteria, such as Escherichia coli (53.8%), Enterococcus (8.9%), and Klebsiella pneumonia (8%), while some patients were followed Gram-positive bacteria and fungal infections. Conclusion The clinically selected antibacterial drugs should be based on the bacterial culture and drug susceptibility test to promote the antibacterial drugs use rationally, frequently changing the medicine and continuing the administration of antibacterial drugs for a long period of time should be avoided.

Objective To investigate the drug utilization of inpatients in neurological rehabilitation department in our hospital. Methods The statistics data of neurological rehabilitation treatment drugs in our hospital from 2008 to 2010 were statistically analyzed, including drug type, the amount of medication, defined daily doses (DDDs) and average defined daily cost (DDC). Results The amount of medication and DDDs increased year by year, the top 3 amount of sales drugs were neurological function and nootropics drugs, the top 3 for DDDs were the promotion of brain metabolism and nootropics drugs. Methylcobalamin tablets, nifedipine and aspirin enteric-coated tablet were in low DDC. Conclusion The use of drug in neurological rehabilitation department in our hospital was in line with the basic features of neuro-rehabilitation specialist.

Objective To explore the effect of Qingretonglin pill combined with levofloxacin tablet on urinary tract infection after spinal cord injury. Methods 55 spinal cord injury patients with urinary tract infection were divided into control group (n=27) and observation group (n=28). Levofloxacin tablets were orally administered in both groups, 500 mg everyday, 14 days. The Qingretonglin pill was also orally administered in the observation group, 1.6 g, 3 times every day, 14 days. The improvement time of frequent micturition, urgent urination and odynuria, and urinary leukocyte number, urinary bacterial quantitative culture changes and the side effect before and after treatment were observed. Results The effective rate was higher in the observation group (89.3%) than in the control group (63%) (P<0.05). The improvement time of frequent micturition, urgent urination and odynuria was shorter in the observation group than in the control group (P< 0.05). The number of urinary leukocyte and urinary bacterial significantly decreased after treatment (P<0.001), and was less in the observation group than in the control group (P<0.05). The rate of side effect was low in both groups, and there was no significant difference (P> 0.05). Conclusion Qingretonglin pill can release the clinical symptoms of urinary tract infection after spinal cord injury, and improve the clearance rate of bacteria.