1.Ethical thinking about the regulation how to deal with unskillful and faulty medical treatment
Yingchun LAN ; Min WANG ; Shouqin XU ;
Chinese Medical Ethics 1995;0(04):-
The regulation how to deal with unskillful and faulty medical treatment is a policy and legal document.It is a implement to the measure how to deal with unskillful and faulty medical treatment. It will make doctor and patients on an equal basis.
2.ESTIMATION OF NITROGEN RETENTION BY N-BALANCESTUDIES AND THE ADEQUATE PROTEIN INTAKEOF PRESCHOOL CHILDREN
Wenzhen PANG ; Eryi XU ; Shouqin LI ; Shuping CHE ; Jingxian MO
Acta Nutrimenta Sinica 1956;0(04):-
Nitrogen balance of normal developed, healthy preschool children 4-7 yrs old, lodged in the kindergartens was studied. 105 preschool children were divided into 15 groups at different protein intakes ranged from 6.28g /MJ to 10.35g/MJ. Prominant correlationship was shown between the intake of protein g/MJ (x) and the retained nitrogen g/kg (y), r= 0.6709, n= 15, p
3.Effects of Intensive Lower Extremity Motor Control Training on Function of Lower Extremitis in Stroke Patients
Xu HU ; Xiang MOU ; Qiang DUAN ; Li MAO ; Mingliang JIN ; Honglei LI ; Shouqin SHAN ; Jiali SUN
Chinese Journal of Rehabilitation Theory and Practice 2015;21(5):552-556
Objective To observe the effects of intensive lower extremity motor control training on the motor function of lower extremity, balance and walking capability of stroke patients. Methods 40 stroke patients were randomized into the intervention group (n=20) and control group (n=20). Both groups received the routine rehabilitation, while the intervention group accepted the lower extremity motor control training in addition for 6 weeks. Before and after 6 weeks of treatments, they were assessed with Fugl-Meyer Assessment of lower extremity (FMA-L), Berg Balance Scale (BBS), Holden Functional Ambulation Category (FAC); their gaits were analysesd with footprint. Results Both groups improved significantly in scores of FMA-L, BBS, FAC and average step length, stride width, walking velocity (P<0.01) after treatment, and improved more in the intervention group than in the control group (P<0.05). Conclusion Intensive motor control training of lower extremity may promote the recovery of motor function of lower extremities, balance and walking ability of stroke patients.
4.The role of integrin involved heparin-binding protein secretion in acute lung injury
Yang LIU ; Shaolin MA ; Xuebin WANG ; Wei XU ; Shouqin ZHANG ; Xiangyu ZHANG
Chinese Journal of Emergency Medicine 2018;27(7):764-768
Objective To study the relationship between heparin-binding protein(HBP) and β2 integrin on the surface of neutrophil in acute lung injury.Methods A total of 30 mice from animal center of Tongji University were divided into control group,CLP group and antibody-treatment group by random number method.Acute lung injury animal model was established by cecal Ligation and puncture in the mice of CLP group and antibody-treatment group.Sham operations were performed on the mice in control group.Mice in antibody-treatment group received anti-CD18 antibody injected via tail vein 30 min before establishing acute lung injury animal model.Twenty-four hours after operation,mice were sacrificed and lung tissue was taken.After HE staining,lung injury were evaluated by Smith score.Lung tissue wet/dry weight ratio,BALF protein level,plasma HBP level and β2 integrin on neutrophil were measured.T test were used to compare the difference among groups.Pearson correlation was used to study the correlation between HBP,integrin and lung injury index.Results Compared with control group,mice in CLP group had higher Smith score(t=10.607,P<0.01),lung wet/dry ratio(t=3.968,P=0.001),BALF protein level(t=4.331,P<0.01) and as well as higher plasma HBP(t=3.515,P=0.002) and β2 integrin(t=4.816,P<0.01) level.After CD18 antibody treatment,anti-treat group mice had lower Smith score (t=2.307,P=0.033),lung wet/dry ratio(t=3.080,P=0.006),BALF protein level(t=2.484,P=0.023) and as well as higher plasma HBP level(t=2.218,P=0.046) than mice in CLP group.Pearson correlation analysis showed HBP had obvious correlation with wet/dry ratio(r=0.527,P=0.017),BALF protein(r=0.508,P=0.022) and as well as β2 integrin(r=0.674,P=0.001).Conclusions Both HBP and β2 integrin involved in the lung injury pathogenesis.HBP level is interrelated with the severity of lung injury.The β2 integrin is associated with the release of HBP by neutrophil.Inhabiting the function of integrin could decrease HBP level and alleviate the severity of lung injury.