0.05).There was significant difference in recovery of AST between two groups(P

The fluctuation of medical staff thoughts and hospital rapid action during SARS epidemic, we name it "hospital phenomenon during SARS", has its specific characteristics. We analyzed this phenomenon from the following points: the conflict between panic response and the duty of the profession, the contradiction between the need to control infection and the available conditions, the special following phenomenon post - diagnosis of SARS and the hospital routine activity and SARS prevention and cure. We conclude that at least three fields should be improved, that is to strength education of duty morals, to normalize the medical procedure, and to build the dual system of hospital' s routine run and rapid action, in order to constructing hospital credit ethic.

Objective To investigate the biological characteristics , therapy selection of tubular breast carcinoma.Relationship between axillary lymph node metastasis and other factors are analyzed retrospectively . Methods Tubular carcinoma patients were collected in our hospital from June ,1987 to March,2014.Paraffin tis-sues were re-checked again by pathology doctors and all patients were performed follow -up by telephone to e-valuate the prognosis .Results Sixty eight cases of tubular carcinoma of the breast were chosen .Axillary lymph node metastasis was closely related to tumor size and tumor grade in our research .In all patients ,only one patient was relapsed ,24 patients died of other diseases ,without distant metastasis or death of breast cancer .Conclusion Tubular breast carcinoma has a good prognosis with low recurrence rate .The treatment of tubular carcinoma is not quite reasonable .Preoperative core needle biopsy and surgery axillary staging should be paid more attention and breast conserving rate is still needed for improvement .

Objective To find a biomechanical evaluation methods of manual performance fatigue,for providing the feasible methods for the hand fatigue of spacesuit glove.Method Twelve females and forteen males in two groups served as the subjects and participated in the experiments of changeless force fatigue,including gripping,pinching and screwing,and took part in the nondimensional force fatigue.Result Manual performance fatigue could be fully evaluated based on gripping,pinching and screwing.The nondimensional force fatigue had widely applied ranges and well veracity.The combination of nondimensional subjective and objective evaluations was the optimal fatigue evaluation method.Conclusion The results can provide the feasible methods for performance evaluation of spacesuit glove system.

The role of insulin pump in the treatment of diabetes is becoming more and more significant. Based on the systematic literature review, collation and analysis, this article introduces the management of insulin pump outside the hospital from the development trend of insulin pump, application and common problems. In order to enhance the therapeutic satisfaction of patients and improve their quality of life, our aims are to put forward the strategy of standardized management and provide a reference for establishing and improving the standardized management system of insulin pump therapy outside hospital.

Objective To observe the pain behavioral performance of rats that different sensory nerve fibers were transected,and examine the expression of brain-derived neurotrophic factor(BDNF) in these models.Methods Twenty-four rats were divided into three groups according to random number table method:SUR group,GS group and SHAM group, which received sural nerve transection, gastrocnemius-soleus nerve transection or sham operation respectively.There were 8 rats in every group.The expression of BDNF in the lumbar 5 DRG and spinal dorsal horn were detected,and the types of damaged cells were also observed.Results In GS group, 50% paw-withdrawal thresholds were significantly decreased on the ipsilateral hind paw compared with baseline and with those in SHAM group,and the paw-withdrawal durations in response to the thermal stimulus increased significantly (P＜0.01 ＝.In contrast, no change was found in SUR group(P＞0.05 ).The expression of BDNF in the lumbar 5 DRG ( (37.87 ± 4.23 ) % ) and spinal dorsal horn ( (21.9 ± 3.1 ) % ) was significantly higher in GS group than in SHAM group( ( 17.31 ± 2.12 ) %, ( 12.6 ± 1.3 ) % ), and no significant difference was found between SUR and SHAM groups(P＞0.05 ).FG opposite cells which also expressed BDNF in GS group were more than those in SUR group ( (47.7 ± 1.8) % and (26.7 ± 2.3 ) % ) (P ＜ 0.01 ＝.The percentage in N200 and FG double positive cells to N200 positive cells in GS group was significantly increased in GS group than those in SUR group ( (47.7 ±1.8 ) %, (26.7 ± 2.3 ) % ) (P ＜ 0.01 ＝.Conclusion The data suggest that injury of the sensory nerve innervating skin does not produce hyperalgesia, but injury of the sensory nerve innervating muscle does.Different kinds of neuron were damaged and the differences of BDNF expression is essential for this difference.

Objective To evaluate the role of protein kinase C (PKC) in reduction of hypoxia-reoxygenation (H/R) injury by hypoxic preconditioning or norepinephrine preconditioning in cultured neonatal rat cardiomyocytes. Methods Primary cultured neonatal rat cardiomyocytes were randomly divided into 6 groups (n = 25 each): control group (group Ⅰ), H/R group (group Ⅱ), hypoxia preconditioning group (group Ⅲ), norepinephrine preconditioning group (group Ⅳ), H7 + hypoxia preconditioning group (group Ⅴ) and H7 + norepinephrine preconditioning group (group Ⅵ). In group Ⅱ , the cardiomyocytes were exposed to 3 h of hypoxia followed by 1 h of reoxygenation. In group Ⅲ, the cells were subjected to 20 min of hypoxia followed by 20 min of reoxygenation before H/R. Norepinephrine was added to the culture medium with a final concentration of 10- 7 mol/L,and then the cells were cultured for 30 min before H/R in group Ⅳ. H7 was added to the culture medium with a final concentration of 5 × 10-5 mol/L, the cells were then cultured for 10 min, and the following procedures before H/R were the same as thase described in group Ⅴ . H7 was added to the culture medium with a final concentration of 5 × 10-5 mol/L, the cells were then cultured for 10 min, and the following procedures were the same as those described in group Ⅵ. The cell survival rate, the activities of LDH and CK in the supernatant, and the content of MDA and activity of SOD in cardiomyocytes were determined. Results The cell survival rate and activity of SOD were significantly lower, while the LDH and CK activities and MDA content higher in group Ⅱ than in group Ⅰ ,in group Ⅴ than in group Ⅲ, and in group Ⅵ than in group Ⅳ (P ＜ 0.01). The cell survival rate and activity of SOD were significantly increased, while the LDH and CK activities and MDA content decreased in group Ⅲ and Ⅳ compared with group Ⅱ (P＜0.01).Conclusion The activiation of PKC is involved in the reduction of H/R injury by hypoxic preconditioning or norepinephrine preconditioning in cultured neonatal rat cardiomyocytes.

Objective To investigate the relationship between serum three triacylglycerol lipase (ATGL) and inflammatory factors in patients with coronary atherosclerotic heart disease (CHD).Methods 135 cases of CHD patients,and 50 healthy people were enrolled in the study.CHD patients were divided into stable angina pectoris (SAP) group (53 cases),unstable angina pectoris (UAP) group(46 cases) and acute myocardial infarction (AMI) group (36 cases) according to relevant diagnostic criteria.The serum levels of ATGL,tumor necrosis factor (TNF-α),interleukin-6(IL-6), interleukin-10(IL-10),1,25 dihydroxy vitamin D3[1,25(OH)2D3] were measured by ELISA, and statistical treatment was performed.Results The levels of ATGL,1,25(OH)2D3 in CHD group were lower than that in control group,and the levels of TNF-α,IL-6 and IL-10 were higher than those of control group(P<0.05).Comparison among different clinical types of CHD patients showed that ATGL,1,25 (OH)2D3 levels of AMI group were significantly lower than those of SAP group and UAP group,while TNF-α,IL-6 and IL-10 were higher than those of SAP group and UAP group(P<0.05);the levels of ATGL,1,25(OH)2D3 in UAP group were lower than those in SAP group,and TNF-α and IL-10 were higher than those in SAP group(P<0.05).Spearman correlation analysis showed that in the CHD group the serum levels of ATGL negatively correlated with TG,LDL-C,LP (a),TNF-α,IL-6,IL-10(r=-0.289,-0.227,-0.359,-0.243,-0.205,-0.337,P<0.05),while positively correlated with age,HDL-C,1,25(OH)2D3(r=0.267,0.356,0.229,P<0.05).Conclusion The ATGL levels in patients with CHD decreases with the increase of inflammatory factors,and plays a certain anti-inflammatory role in the progression of CHD.It can be used as a monitoring indicator to reflex the progress of CHD.

Objective To search for perfect and logical evaluation indexes of range of motion of manual performance and maximal voluntary range of motion. Methods From mechanism of hand movement and characteristics of manual action,some relative comprehensive evaluation indexes on range of motion of manual performance were provided.Twenty six undergraduates (14 male and 12 female)participated in the test for 16 indexes. Results The maximal voluntary range of motion of thumb,four fingers and wrist were obtained. Conclusion The results can provide foundation for ergonomics design of spacesuit gloves.

Objective To quantify dose variations of the parotid glands and spinal cord in nasopharyngeal carcinoma (NPC) patients during helical tomotherapy (HT) by using megavolt (MV) CT and planned adaptive application. Methods Five patients with advanced local-regional NPC were treated by HT with a prescription dose of 70 Gy in 35 fractions in primary tumor and involved lymph nodes. Daily MV CT scans were registered with the planning CT images. The parotid glands were re-contoured every 4 fractions to a total of 45 times, and location of the spinal cord were corrected by MVCT IGRT system every 2 fractions to a total of 85 times. The actual doses delivered to these organs were evaluated by using the planned adaptive application software of HT system. Results At the end of therapy, the mean volume of the parotid gland was decreased by 42% (left) and 33% (right) , respectively. The average V1 of the parotid was increased by 26. 0% (left) and 31.4% (right), and the D50 increased by 15. 8% (left) and 17. 3% (right), respectively. The average Dmax of the spinal cord was increased by 1.3%. Conclusions During HT, the parotid glands receive a higher actual dose due to the volume shrinkage, while the Dmax of the spinal cord changes little. By using adaptive radiation therapy technique, constant monitoring anatomic changes of organs at risk and selective replanning are necessary during radiation therapy for NPC.