Objective To compare the clinical effects of needle buried suture and the posterior wall of vagina mucosa excision vaginal tightening surgery for the treatment of mild to moderate vaginal relaxation.Methods A total of 71 patients with mild to moderate vaginal relaxation were randomly divided into observation group (39 cases) and control group (32 cases).The patients in the observation group were given buried lead needle suture,and the control group were treated with posterior wall of vagina mucosa resection.Analysis of two groups was conducted in patients with operation time,intraoperative bleeding,vaginal secretion color,postoperative wound healing and complications;sexual satisfaction was evaluated after 6,12 and 24 months in two groups of patients.Results There was no significant difference between two groups in operation time and vaginal secretion color (P＞ 0.05).Intraoperative blood loss was much more in the observation group than those in the control group,with statistically significant differences between the two groups [(6.23±2.43) ml vs (15.79 ± 7.31) ml,P＜0.05)].The follow-up for a number of months showed that sexual satisfaction had significant difference between the two groups (P＜0.05).None of the patients had rectal or urethral injury,no fistula,incision infection or other complications occurred,and the incision healed in stage Ⅰ.Conclusions For patients with mild to moderate vaginal relaxation,buried lead needle suture vaginal tightening surgery does not damage the vaginal mucosa,no scar,and fewer complications,which is a more simple and effective method to improve the quality of life in patients with vaginal relaxation.

Objective:To evaluate the clinical effect of autologous fat graft in the correction of varying degrees of nasolabial fold drop.Methods:From September 2018 to September 2021, 96 patients mean age of 41 years, with range from 36 to 50 years with nasolabial fold drop admitted in our hospital were treated with autologous fat graft, the improvement of nasolabial fold drop was evaluated by the change of severity (wrinkle severity rating scale, WSRS) to observe the clinical effect and complications of autologous fat graft.Results:Among 96 patients, 75 cases were accepted once treatment, the other 21 cases were accepted twice treatment. The patients were followed up for 12 months, 58 cases (60.4%) of patients had significant improvement, 30 cases (31.3%) of patients had moderate improvement, and 8 cases (8.3%) of patients had slight improvement. There were no complications except mild bruising in early postoperative period in some patients.Conclusions:Autologous fat graft in the correction of varying degrees of nasolabial fold drop is safe and effective, which could be popularized in clinical practice.