1.Study on the Attributive Zang-Fu of TCM to the EBV Infection According to the Malignant Tumor
Xiaojun ZHOU ; Shizheng WANG ; Daofa TIAN
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(07):-
Objective To study on the attributive Zang-Fu of TCM to the EBV infection according to the malignant tumor. Methods The malignant tumor in-patients were reviewed to survey the EBV infection, and the nasopharyngeal carcinoma infected the EBV were reviewed to survey the transfer cancer occurance. Results Of the malignant tumor in-patients, there were high EBV infection appearances in the nasopharyngeal (87.5%), the liver (15.0%) the lung (8.3%). There was no EBV infection in the other malignant tumor in-patients. The transfer cancer of the nasopharyngeal carcinoma occurred in the liver (40%) and lung(25%). Conclusion The attributive Zang-Fu of TCM to the EBV infection are liver and lung.
2.Vacuum sealing drainage with biological foam dressing accelerates the healing of chronic wounds:changes in gelatinase activity
Ping YANG ; Hongwei YAN ; Hui GONG ; Hua LIU ; Zhimin NI ; Shizheng TIAN
Chinese Journal of Tissue Engineering Research 2015;(25):4064-4068
BACKGROUND:Studies have shown that vacuum sealing drainage can accelerate wound healing through increasing the wound blood flow, but its influence on activated gelatinases in human chronic wound stil lacks corresponding research. OBJECTIVE:To observe the effect of vacuum sealing drainage on the activity of gelatinase during the healing of chronic wounds. METHODS:Total y 96 trauma patients admitted at the People’s Hospital of Hubei University of Medicine from April 2013 to January 2014 were divided into two groups:52 patients in chronic wound group were treated with vacuum sealing drainage and 44 in control group treated with wound drainage at 3 days after removal of breast cancer. In the chronic wound group, exudates from pressure sores and skin necrosis after removal of breast cancer were col ected as samples A and B;exudates from two cases of venous stasis ulcer were col ected as samples C and D;exudates from traumatic skin wounds col ected as sample E. RESULTS AND CONCLUSION:TLC analyzer showed that:after 15-day negative pressure therapy, activities of matrix metal oproteinase 2 in sample A with low activity of gelatinase, matrix metal oproteinase 9 in sample B, matrix metal oproteinase 2 and 9 in samples C, D, E were al increased significantly (P<0.05);however, the activities of matrix metal oproteinase 9 in sample A with high activity of gelatinases and matrix metal oproteinase 2 in sample B were reduced significantly after treatment (P<0.05). In addition, no significant difference was found in the activity of matrix metal oproteinase 2, matrix metal oproteinase 9 and activated gelatinase betweenthe chronic wound group and control group (P>0.05). These findings indicate that the variation of activated gelatinases activity in human chronic wounds may be the reason why the chronic wounds cannot be healed for a long time, but vacuum sealing drainage can regulate the activity of activated gelatinases in chronic wounds.