1.THE PATTERN OF MUSCLE ARRANGEMENT OF THE ESOPHAGOGASTRIC JUNCTION
Acta Anatomica Sinica 1957;0(04):-
The muscle arrangements of esophago-gastric junction were observed in 30 human specimens. Muscles of the esophago-gastric junction consist of two layers-an outer longitudinal oblique layer and an inner circular oblique layer. At the top of esophageal vestibule 2 superficial muscle bundles may be identified. They are continuous with longitudinal muscle fibers of the tubular esophagus and runs to the stomach. The deep circular layer of the tubulovestibular junction is thicker than that of the tubular esophagus. It looks like a sphincter which lies 27.06 2.11mm above the cardiac incisure. At the middle segment of the esophageal vestibule some of the circular muscle fibers turn into spiral or loop forms. At the terminal portion of the vestibule two semicircular muscles separately localized towards the fundus and the lesser curvature of the stomach. They overlap at the back or at the front of the stomach. A small bundle opposite the gastric sling fiber demarcates the right margin of the esophago-gastric junction.
2.Advancement of non-invasive coronary artery angiography
Chinese Journal of Interventional Imaging and Therapy 2009;6(4):371-374
Non-invasive coronary artery angiography is one of the hotspots of imaging.This article reviewed the status and the relevant advancement of the cardiac EBCT, DSCT, MSCT and MR imaging.
3.Therapeutic Analysis of Hepatic Artery Chemoembolization in 60 Patients with Middle-Late Hepatocarcinoma
Journal of Practical Radiology 2000;0(02):-
Objective To evaluate the therapeutic effect of middle-late hepatocarcinoma by transcather arterial chemoembolization (TACE).Methods 60 patients with middle-late hepatocarcinoma were undergone selective hepatic artery catheter purfusion chemotherapy combined with iodized oil embolism through femoral artery using Seldinger technique totally . All patients 140 times . Results There were significant effect in 36 cases (60%),effect in 19 cases (31.7%) and stable in 5 cases(8.7%) after treatment.The survival rate has been improved,38 cases ( 63.3%) have survived for more than 12 months . Conclusion For the patients with middle-late hepatocarcinoma,TACE is curative effect,it can prolong survival time significantly and improve patient’s life quality.
4.DETERMINATION OF THE DIRECTION OF THE NUTRIENT A RTERIES OF THE FEMUR IN THE HUMAN FETUS
Mingyang LI ; Wengui WANG ; Shixin JIN
Acta Anatomica Sinica 1954;0(02):-
Forty human fetuses ranging from C-R length 72 mm (which corresponds to a developmental stage of the second week in the third month of the embryo) to fullterm were used to investigate the nutrient arteries of the femora using the dissection method and roentgenography. In comparison with adults, there are apparently more (P
5.Application of fluorescence imaging in the research of tumor
Shixin ZHANG ; Mingxin CHEN ; Fangqiu LI
Journal of Medical Postgraduates 2004;0(02):-
Fluorescence imaging of animal in vivo is to tag cell or DNA with fluorescence reporter gene, and then detect the fluorescence using sensitive optics apparatus. With this system, researcher can observe tumor growth, metastasis and angiogenesis in vivo, and reliable information for tumor diagnosis and treatment will be provided for researcher.
6.The effects of intranasal budesonide on eosinophils in nasal polyps
Shixin ZHENG ; Li YAO ; Ying XIAO
Chinese Journal of Primary Medicine and Pharmacy 2005;0(02):-
Objective To study clinicopathologic significance of eosinophils in human nasal polyps and the effect of corticosteroids.Methods 90 cases of nasal polyps were divided into two group randomly:corticosteriods group(n=30) with topical application of budesonide(BUD,400?g/d) for 14 days before endoscopic polypectomy,and control group(n=60) without BUD before surgery.All cases were stained with HE.Results Eosinophils showed higer in the group of nasal polyps than in the group of norm al inferior turbinate(P
7.Combined use of near-infrared and other technologies in tumor research
Mingxin CHEN ; Shixin ZHANG ; Fangqiu LI
Journal of Medical Postgraduates 2003;0(09):-
Near-infrared technology can be used as an auxiliary means for the early diagnosis of cancer and for surgical resection of tiny lesion that can not be discriminated by naked eyes,but it can not satisfy the purpose when used alone.Thus,we have developed an integrated technique by combining near-infrared and other technologies,and extended the scope of its application.This article reviews the advances of several integrated techniques applied to tumor research,including double labeled technology of nuclide and near-infrared,the combination of near-infrared and fluorescence resonance energy transfer,the combined use of near-infrared and endoscopy,and the integration of near-infrared with carbon nanotubes.
9.Effects of Xuesaitong on the expression of NF-κB in rats'hippocampus after global cerebral ischemia/reperfusion
Shengguang YANG ; Xiaolin DUAN ; Shixin YAN ; Ke SU ; Feng LI
Journal of Chinese Physician 2012;14(3):318-321
Objective To investigate the expression of NF-κBp65 in hippocampus after the XST intervention therapy in the SD rats with global cerebral I/R injury and testify the protective effect of XST after global cerebral I/R injury.Methods 72 healthy SD rats were randomly divided into 3 groups,sham operation(SO) group ( n =24),I/R group( n =24) and XST group( n =24).The model of acute global cerebral ischemia/reperfusion (including:I/R and XST group) injury was produced by means of simple Pulsinelli- brierley's four arteries occlusion method.H.E.staining was performed to detect the number of surviving neurons and TUNEL was used to detect the rate of neurons apoptosis.The expression activation of NF-κB p65 in hippocampus comu-ammonis ( CA1 ) region were examined by immunohistochemical method (SABC).Results The survival pyramidal neurons in the XST group continued to increase,and it was significantly more than the I/R group at each time-point after reperfusion[ (99.23 ±4.22)/mm vs (75.83 ±7.17 )/mm,(80.93 ± 5.36)/mm vs (51.50 ± 8.26 )/mm,(103.24 ± 5.48 )/mm vs (35.67 ± 13.17 )/mm,( 126.22 ± 7.54 )/mm vs (9.83 ± 4.71 )/mm ],the differences were statistically significant ( P <0.01 ).The apoptosis rate of pyramidal cell in the XST group at each time-point were more significantly reduced than the I/R group [ ( 8.82 ± 2.71 ) % vs ( 22.58 ± 4.68 ) %.( 19.15 ± 6.23 ) % vs (42.68 ± 3.04 ) %,( 11.82 ± 2.87 ) % vs ( 55.51 ± 6.81 ) %,( 8.44 ± 3.23 ) % vs ( 71.69 ± 7.71 ) % ],the differences were statistically significant ( P <0.01 ).The positive neurons of NF-κBp65 expression in the XST group at different time-points were significantly less than the L/R group[ ( 13.20 ±2.50) vs ( 18.00 ± 1.87),(8.20 ±5.31) vs (41.60±3.65),(6.70±3.36) vs (55.30±5.10),(7.10±3.57) vs (72.80 ±4.71)],the differences were statistically significant ( P < 0.05,P < 0.01 ).Conclusions After global cerebral ischemia/reperfusion,XST could protect the brain from global cerebral ischemia/reperfusion injury by holding up the expression of NF- kappaB p65,and inhibiting neuronal apoptosis,and increasing the number of surviving neurons.Thus,the results of this experiment could provide a powerful and weighty objective indication for XST being used during cerebral resuscitation.
10.Expression of caveolin-1 in osteosarcoma and its significance for clinicopathological features
Jichen WANG ; Shixin BAO ; Manxi BAO ; Hai LI
Clinical Medicine of China 2011;27(10):1097-1099
Objective By detecting the expression of caveolin-1 in osteosarcoma tissues,to explore its possible roles in the occurrence,progress and metastasis of osteosarcoma and its relationship with clinicopathological features.Methods The expression level of caveolin-1 protein in 48 osteosarcoma tissues and 24 normal bone tissues were detected by immunohistochemistry of SP method.Its relationship with clinical and pathological features were also analyzed.Results among the 48 osteosarcomas examined,38 were stained weak or negative for caveolin-1,whereas the strong caveolin-1 staining was observed in all the 24 normal bone tissues.The absorbent optical density value of caveolin-1 protein in osteosarcoma tissues and normal bone tissues were(0.2292 ± 0.0329) and(0.6428 ± 0.0028),respectively.The expression of caveolin-1 in osteosarcoma tissues was significantly lower than that in normal bone tissues (t =21.48,P < 0.01 ).Caveolin-1 protein expression was significant correlated with the pulmonary metastasis of tumors ( t =11.84,P < 0.05 ),but had no correlation with nge,sex,tumor size and pathologic grades.Conclusion The low expression of caveolin-1 may participate in osteosarcoma invasion and metastasis,and may be a new prognostic molecular marker for osteosarcoma and a new therapeutic target for tumor.