Objective:To investigate the clinical and experimental effect of Zhao's Weitiao Ⅲ decoction on colorectal cancer.Methods:Clinical study:After oral administration of Zhao's Weitiao Ⅲ decoction,main symptoms,quality of life,clinical curative effect and survival rate of the patients were observed.Experimental study:Zhao's Weitiao Ⅲ decoction was observed by the antitumor effect on transplanted sarcoma,the influence on cytokine of experimental animal and the inhibition and apoptosis of HT-29 and LOVO cells.Results:Clinical study:Zhao's Weitiao Ⅲdecoction could improve patients’ main symptoms(the total effective rate was 89.52%),improve patients’ quality of life(P