1.Experimental study of animal chronic myocardial ischemia model by ultrasonic integrated backscatter and doppler tissue imaging
Jing XU ; Baozhen ZHAO ; Zhong WANG ; Junyan GU ; Shipin LU
Journal of Medical Postgraduates 2003;0(10):-
Objective: To establish porcine chronic ischemic myocardium model and to evaluate ultrasonic integrated backscatter(IBS) and Doppler tissue imaging(DTI) in detecting this model. Methods: An Ameroid constrictor was placed around the porcine proximal left circumflex artery. The calibrated average image intensity (%AⅡ), cyclic variation of IBS (CVIB), the subendo-epicardical gradient index (TGI) and the spectrum of left ventricular papillary muscle level short axis view (LVPM-SAM) and apical four chamber view (AP-4CV) were measured at normal state, 2 w, 4 w, 6 w and 8 w after Ameroid placement. Results: Normal %AⅡ, CVIB and TGI were 2.29?0.32,(9.69?2.22)dB and 0.22? 0.08 respectively. After Ameroid placement, the %AII increased gradually, the CVIB decreased gradually, and the decrease was higher in subepicardium than that in subendocardium. The most obvious decrease of TGI occurred from 2 w to 4 w after Ameroid placement and became zero at 8 w(P
2.INFLUENCE OF GARDENIA YELLOW ON CCl_4- HEPATOTOXICITY IN MICE
Dequan ZHANG ; Feijie LU ; Jianxiang TAI ; Shipin ZHAO ; Guixiang FU ; Qin FU ;
Acta Nutrimenta Sinica 1956;0(03):-
Objective: To study the protective function of Gardenia yellow (GY) against CCl 4 induced hepatotoxicity in mice.Methods: Healthy Kunming male mice, weighting (20?2) g, 10 per group were randomized into 5 groups:control group, CCl 4 injured group, low dose group(CCl 4 injured+0.1 ml GY solution), medium dose group(CCl 4 injured+ 0.2 ml GY solution) and high dose group(CCl 4 injured+0.4ml GY solution). GY solution was given i.g. 5 d prior to CCl 4 injury. Serum glutamate pyruvate transaminase(SGPT) and glutamic oxaloacetic transaminase(SGOT) and lactic dehydrogenase(LDH) activities were determined 18 h after CCl 4 injury. Hepatic malondialdehyde(MDA), glutathione(GSH) and liver index were also detected. Results: In GY treated groups, the increases of serum SGOT, SGPT, LDH activities and liver GSH were inhibited obviously. The elevations of MDA and liver index were prevented significantly. The lesions in liver lobule were ameliorated obviously. Conclusion: Gardenia yellow can protect against CCl 4 induced hepatotoxicity.
3.Diagnosis and treatment of right middle lobe torsion after thoracoscopic lobectomy of right upper lobe: report of two cases
Chengguang HU ; Shipin GUO ; Jianhong LIAN ; Diansong MA ; Kang ZHENG ; Zhilong LI ; Guanhua LIU ; Yanli ZHAO ; Yanyan MA
Chinese Journal of Thoracic and Cardiovascular Surgery 2018;34(4):250-251