A 81-year-old man was referred to our hospital for treatment of a skin ulcer of the right anterior crus. After 2 months left common femoral artery-right popliteal artery bypass, graft infection was occurred and methicillin-sensitive Staphylococcus aureus was found in the bacterial culture. The wound was extended in order to decide the extent of graft infection, but graft healing was totally insufficient. All of the graft was excised, and right axillo-popliteal bypass using 8mm Bionit graft was performed. The graft was passed through lateral femoral. Thus, in this case the graft excision was necessary, but major amputation could be avoided by successful revascularization.