1.Clinical Usefullness of a Database Obtained from the Experience of Physicians Prescribing Herbal Medicines : Report on a Questionnaire Regarding Treatment for Chillness of the Limbs
Norio IIZUKA ; Akihiro UCHIZONO ; Takaaki KITANO ; Yasumasa SATO ; Sadahiro SEMPUKU ; Hajime NAKAE ; Yoshihiro NISHIDA ; Ginryu FUKUMOTO ; Kiyoshi MINAMIZAWA ; Kojiro YAMAGUCHI ; Shinei RYU
Kampo Medicine 2014;65(2):138-147
Aim of the present study was to statistically evaluate the examination rule with use of a questionnaire obtained from physicians regarding treatment for chillness of the limbs, and to prove the clinical usefulness of the database. The database showed that tokishigyakukagoshuyushokyoto was the most frequently used to treat chillness of the limbs, and subsequently keishikajutsubuto, hachimijiogan, and tokishakuyakusan were ranked as drugs with wide use. When physicians determined a kampo formulation suitable for each patient, they used findings specific for the kampo formulation, but not uniform findings obtained from the four traditional examination methods (i.e., inspection, listening and smelling, interviewing, palpitation). There was a statistical difference in the selection mode of drugs among physicians. In a simulation obtained from a questionnaire, there was a positive association between time (time X) to the start of becoming physically warm in the limbs, and time (time Y) to remission (R2 = 0.971, P = 0.014). The formula (Y = 4.379 X−0.519), which could predict time Y on the basis of information on time X, was able to accurately monitor the clinical courses of 7 responders to treatment for chillness of the limbs. Taken together, these results strongly suggest that the database constructed in the present study may be useful for evaluation of traditional Kampo medicine, and might allow us to perform more fittingly personalized Kampo medicine in the near future.
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