1.Development and application of simple oxygenation respirator
Chengli XU ; Xia JIANG ; Jingxue HU ; Tao LU ; Shijin PAN
Chinese Medical Equipment Journal 2003;0(12):-
Simple oxygenation respirator is mainly used for respiratory failure patients who are failed in being treated with open positive pressure.It can markedly improve the oxygenation concentration and ventilation.Most respiratory failure patients can avoid using mechanical respirator if it is used adequately.Respiratory model Ⅰ,Ⅱ,Ⅲ can be applied according to different type of respiratory failure respectively.It is also very effective to cerebral vascular diseases.The structure of respirator is fit for human physiology without interfering cardiac and pulmonary functions.It has no contraindications and side effect.It is simple,cheap and practical.
2.Development and validation of an individualized nomogram for early prediction of the duration of SARS-CoV-2 shedding in COVID-19 patients with non-severe disease.
Shijin YUAN ; Yong PAN ; Yan XIA ; Yan ZHANG ; Jiangnan CHEN ; Wei ZHENG ; Xiaoping XU ; Xinyou XIE ; Jun ZHANG
Journal of Zhejiang University. Science. B 2021;22(4):318-329
With the number of cases of coronavirus disease-2019 (COVID-19) increasing rapidly, the World Health Organization (WHO) has recommended that patients with mild or moderate symptoms could be released from quarantine without nucleic acid retesting, and self-isolate in the community. This may pose a potential virus transmission risk. We aimed to develop a nomogram to predict the duration of viral shedding for individual COVID-19 patients. This retrospective multicentric study enrolled 135 patients as a training cohort and 102 patients as a validation cohort. Significant factors associated with the duration of viral shedding were identified by multivariate Cox modeling in the training cohort and combined to develop a nomogram to predict the probability of viral shedding at 9, 13, 17, and 21 d after admission. The nomogram was validated in the validation cohort and evaluated by concordance index (C-index), area under the curve (AUC), and calibration curve. A higher absolute lymphocyte count (
Aged
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Aged, 80 and over
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Antibodies, Viral/blood*
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Area Under Curve
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COVID-19/virology*
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Female
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Humans
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Lymphocyte Count
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Male
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Middle Aged
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Nomograms
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Proportional Hazards Models
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Retrospective Studies
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Viral Load
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Virus Shedding