1.Reasons and Countermeasures of Discrepancy of the Account in Inventory Management of Automatic Oral Single Dose Drug Dispensing Machine
Hang HUANG ; Liman QIAO ; Shishi ZHENG ; Shihui BAO
China Pharmacy 2015;(25):3592-3594
OBJECTIVE:To explore the reasons and countermeasures of discrepancy of the account in inventory management of automatic single dose drug dispensing machine. METHODS:The discrepancy information of using sub charter in the process of inventory management from Feb. to Jun. 2014(before management)was collected,the causes were analyzed and countermeasures were put forward and carried out;then management results were evaluated via the discrepancy information from Jul. to Nov. 2014 (after management). RESULTS & CONCLUSIONS:For the relative discrepancy factors such as peeling medicine,adding medi-cine and recording information,etc.,which appeared in each link,the management was strengthened in terms of drug,machine and personnel like limiting scattered drug product rules,modifying the machine parameters settings,strengthening the training and testing of machine operators;and deliver inside account discrepancy rate was decreased from 3.34% to 0.79%. Improvement of the relative system with effective countermeasures can reduce the account sub charter discrepancy rate.
2. Advances in the research of application of artificial intelligence in burn field
Haihang LI ; Zhenxing BAO ; Xiaobin LIU ; Shihui ZHU
Chinese Journal of Burns 2018;34(4):246-248
Artificial intelligence has been able to automatically learn and judge large-scale data to some extent. Based on database of a large amount of burn data and in-depth learning, artificial intelligence can assist burn surgeons to evaluate burn surface, diagnose burn depth, guide fluid supply during shock stage, and predict prognosis, with high accuracy. With the development of technology, artificial intelligence can provide more accurate information for burn surgeons to make clinical diagnosis and treatment strategies.
3.Investigation and analysis of the needs of community pharmaceutical care in Wenzhou city
Shihui BAO ; Zhengfeng LIN ; Ying ZHENG ; Yao PAN ; Junbang LIN
China Modern Doctor 2014;(30):108-111
Objective To survey the current status of community pharmacy care, analyze the needs of both community residents and medical staff for community pharmacy care, and provide references for improving the quality of communi-ty pharmacy care and policy making. Methods The form of questionnaire was taken for community residents and com-munity pharmacists from community health service centers, a random survey was conducted to collect information for statistical analysis. Results Sixty-six point eight percent of community residents selected community health service center as the main choice for obtaining drugs. The residents' home-stored drugs were mainly for cold/fever, abdominal pain/diarrhea, common chronic diseases, external wounds treating and antibacterial. Only 16.8%of community residents stored the drugs according to instructions, 70.6% would use antibacterial drug by themselves under various circum-stances, 82.8% thought there were errors in drug usage, over 98.0% of community pharmacists recognized the impor-tance of pharmaceutical care and the needs for further development. 89.1% of them were eager to improve their own capability of serving and have the needs of collaboration with large hospitals. Conclusion Improper drug usage and storage are common among community residents. Their expectations for pharmaceutical service are increasing. And community pharmacists expected to improve their own pharmacy service capability.
4.Study on Preventive Effects and Mechanism of Ginsenoside Rg 1 on Focal Cerebral Ischemia-reperfusion Injury Model Rats
Wenwen WU ; Shihui WU ; Chunhong LIU ; Cuifen BAO ; Lianqiu MIN
China Pharmacy 2020;31(11):1287-1293
OBJECTIVE:To st udy preventive effect and mec hanism of ginsenoside Rg 1 on focal cerebral ischemia-reperfusion injury(CIRI)model rats. METHODS :Totally 78 SD rats were randomly divided into sham operation group ,model group , butylphthalide control group (positive control ,10 mL/kg),ginsenoside Rg 1 low-dose,medium-dose and high-dose groups (10, 20,40 mg/kg),with 13 rats in each group. Administration groups were give relevant medicine intraperitoneally ,sham operation group and model group were given constant volume of normal saline intraperitoneally ,once a day ,for consecutive 7 d. After medication,except for the sham operation group ,focal CIRI model was induced by middle cerebral artery occlusion (MCAO) method in other groups. After modeling ,neurological deficit scoring was performed according to the modified neurological difict scoring standard ; TTC staining was used to detected the percentage of cerebral infarction of rats ;the cerebral water content was measured by dry/wet weight method ;serum contents of IL- 1β and IL-6 were detected by ELISA ;the protein expressions of p-p 38 MAPK and p-NF-κB p65 in cerebral tissue were determined by immunohistochemistry and Western blotting assay. RESULTS : Compared with sham operation ,neurological deficits score ,percentage of cerebral infarction and cerebral water content ,serum contents of IL- 1β and IL-6,positive expression numbers of cells and protein expressions of p-p 38 MAPK and p-NF-κB p65 in cerebral tissue were increased significantly in model group (P<0.05 or P<0.01). Compared with model group ,above index levels of administration groups were all decreased significantly (P<0.05 or P<0.01),and the effect of ginsenoside Rg 1 had a dose-dependent trend ;there was no significant difference of all above indexes between ginsenoside Rg 1 middle-dose,high-dose groups and butylphthalide control group (P>0.05). CONCLUSIONS :Ginsenoside Rg 1 has a certain preventive effect on focal CIRI model rats ,the mechanism of which may be associated with down-regulating the protein expression of p-p 38 MAPK and p-NF-κB p65,inhibiting the release of inflammatory factors such as IL- 1β and IL-6.