1.Effects of Moxibustion and Goshazinkigan for Spontaneous Fatty II Diabetes Rat
Kaori TAMAKI ; Norimasa TANIGUCHI ; Izuru MATSUHATA ; Shigeyuki KANAI
Kampo Medicine 2005;56(4):555-560
In order to examine the effectiveness of moxibustion and Goshajinkigan for diabetes we investigated using Otsuka Long-Evans Tokushima Fatty (OLETF) rats and Long-Evans Tokushima Otsuka (LETO) rats. 18 male OLETF rats (5 weeks old) and 6 male LETO rats (5 weeks old) were divided into 4 groups. Group I rats were given trial moxibustion (BL 20, BL 23). Group II rats were administered Goshajinkigan (100mg/kg). Group III (OLETF) and IV (OLETF) rats were untreated as controls. In each group, we measured body weight (BW), blood sugar (BS), urine albumin (UA), pain-related time (PRT) and blood flow volume (BFV) before and after the experiment. Moreover, kidney and pancreas tissues were observed.
In groups I, II and III, BW, BS and UA increased in comparison with that of group IV, as the rats grew older. But groups I and II showed suppressed increases, in comparison with that of III group. After stimulation groups I and II showed reaction sensitivity, in comparison with group III. Group I showed a suppressed decrease of BFV. Tissue samples showed no serious change.
These findings suggest that moxibustion and Goshajinkigan inhibited some quantity of the progress of diabetic disease.
2.Factors That Influence Functional Prognosis in Elderly Patients with Hip Fracture
Shigeko TAKAYAMA ; Masayuki IKI ; Yukinori KUSAKA ; Haruki TAKAGI ; Shigeyuki TAMAKI
Environmental Health and Preventive Medicine 2001;6(1):47-53
The purpose of this study was to evaluate in aged patients with hip fracture, the degree of recovery at discharge and after discharge relative to the pre-fracture walking level, to clarify the factors involved in unsuccessful recovery. The patients were 189 patients aged 60 years and older who underwent surgery between 1988 and 1994. Patients who died within 1 year or lacked data on walking were excluded. Multiple logistic regression analysis was applied to data on the walking level before fracture, that at discharge, and the best walking level after discharge, to clarify factors involved in unsuccessful recovery. The rate of recovery to the pre-fracture level was 55.1% at discharge. Unsuccessful recovery at discharge was influenced by prior dementia, a history of cerebrovascular diseases, and an age of 85 or more years. Analysis showed an “after-discharge” recovery rate of 63.2%. Prior dementia and the residence outside one’s own home influenced unsuccessful recovery rate. These findings suggested that it is important to provide patients with such factors a more effective postoperative rehabilitation program not merely the standard rehabilitation program. In addition, a walking rehabilitation program should be offered to those who were re-hospitalized or admitted to other health care facilities.
Walking
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Personal failure
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Rehabilitation therapy
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Dementia
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seconds
3.Rate of Mortality with Hip Fracture and its Prognostic Factors in an elderly Japanese population
Shigeko TAKAYAMA ; Masayuki IKI ; Yukinori KUSAKA ; Haruki TAKAGI ; Shigeyuki TAMAKI
Environmental Health and Preventive Medicine 2000;5(4):160-166
The purpose of this study was to clarify the survival rates and prognostic factors in elderly Japanese patients with hip fractures. This study investigated the outcome of 256 patients aged 60 years and older with surgically treated hip fractures. Information including age, gender, duration of hospitalization, place of residence before fracture and at discharge, and level of mobility before fracture and at discharge was obtained from patient records. The survival of the patients after discharge was determined by mail surveys supplemented with telephone inquiries.The observed survival rates were significantly lower than the expected survival rates (p<0.001, by Mantel Haenszel test). The short-term mortality rates were 6% for six months and 12.7% for one year, which were lower than previously reported rates in Western countries. Significantly higher hazard ratios (HR) for mortality adjusted for age and gender were observed in patients who had lived in places other than their own home before fracture (HR=2.67(1.63-4.3)), were discharged to places other than their own home (Nursing home HR=2.25 (1.24-4.1) or to a non-orthopedic unit (HR=5.95 (3.12-11.34)), those requiring full-time assistance for mobility at discharge (HR=5.71 (3.59-9.01)), and those who had stayed in a hospital for fewer than 40 days (HR=2.20 (1.38-3.51)). After adjusting for the effects of all the potential prognostic factors, discharge to places other than their own home and the lowest level of mobility at discharge remained significant factors causing adverse effects on survival.Therefore, to improve the prognosis, patients should be allowed to recover to a level at which they can ambulate with some assistance, enabling them return to their own homes.
survival aspects
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seconds
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Japanese language
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prognostic
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Mortality Vital Statistics