Stellate ganglion radiation by polarized light (SGR) and placebo radiation were applied to healthy adults to compare the effects on the autonomic nervous system and electroencephalogram (EEG) of these radiations and the following results were obtained:
(1) The pulse rate tended to decrease during and after both SGR and placebo radiation. In contrast, the systolic blood pressure tended to increase during and after both radiations. No significant difference between radiations was found in either the pulse rate or systolic blood pressure. The coefficient of variation of the pulse rate (CV-PR), which reflects conditon of the cardiovascular parasympathetic nervous function, tended to increase during and after SGR and tended to decrease during placebo radiation. The value of CV-PR was significantly higher after SGR than after placebo radiation.
(2) The surface skin temperature of the lower extremities after SGR was slightly higher than that after placebo radiation, but the temperature of the upper extremities did not show any difference between SGR and placebo radiation.
(3) The relative power of alpha-2 wave as determined by quantitative EEG tended to be greater during and after SGR than during and after placebo radiation. The value 10min after SGR was significantly higher than after placebo radiation.
These results suggested that SGR activated the cardiovascular parasympathetic nervous function and relatively suppressed the cardiovascular sympathetic nervous function. We concluded that SGR influences not only the cardiovascular autonomic nervous system and surface skin temperature of the lower extremities, but also a wide range of EEG.

Background: Cerebral blood flow (CBF) has direct effects on neuronal function and neurocognitive disorders. Oxidative stress from abdominal aortic surgery is important in the pathophysiology of CBF impairment. We investigated the effect of edaravone on the pial arteriolar diameter changes induced by abdominal aortic surgery and the involvement of the endothelium in the changes. Methods: The closed cranial window technique was used in rabbits to measure changes in pial arteriolar diameter after the unclamping of abdominal aortic cross-clamping with an intravenous free radical scavenger, edaravone (control group [n = 6], edaravone 10 μg/kg/min [n = 6], 100 μg/kg/min [n = 6]). Pial vasodilatory responses to topical application of acetylcholine (ACh) into the cranial window were investigated before abdominal aortic cross-clamping and after unclamping with intravenous administration of edaravone (control group [n = 6], edaravone 100 μg/kg/min [n = 6]). Results: Aortic unclamping-induced vasoconstriction was significantly attenuated by continuous infusion of edaravone at 100 μg/kg/min. Topical ACh after unclamping did not produce any changes in pial arteriolar responses in comparison to before aortic cross-clamping in the control or edaravone groups. The changes in the response to topical ACh after unclamping in the saline and edaravone groups did not differ significantly. Conclusions Free radicals during abdominal aortic surgery might have contracted cerebral blood vessels independently of endothelial function in rabbits. Suppression of free radicals attenuated the sustained pial arteriolar vasoconstriction after aortic unclamping. Thus, the free radical scavenger might have some brain protective effect that maintains CBF independently of endothelial function.