Fisher syndrome is characterized by ophthalmoplegia, ataxia and areflexia after preceding infection. The ophthalmoplegic symptom is described in a volume of Yomeibyo of the Shokan Ron, the classic Chinese encyclopedia of medical treatment. The Shokan Ron recommends Dai-joki-to as a treatment for this symptom. Accordingly, we administered Dai-joki-to to one patient diagnosed with atypical Fisher syndrome. The result was a prompt reduction of the ophthalmoplegic symptom in the patient. As Fisher syndrome is not a critical disease, Dai-joki-to administration should be considered as an alternative treatment to plasmapheresis.