1.Seroprevalence of susceptibility to morbillivirus infection on giant panda in captivity
Hiroshi KAMATA ; Shigeo OHBA ; Hideo KIBA ; Shigehisa TSUMAGARI ; Tsunco SATO ; Kiichi KA-NAYAMA ; In-Jen PAN ; Toshi WATANABE ; ZHANG Zhi-he ; HOU Rong ; WANG Cheng-dong ; SHEN Fu-jun ; ZHANG Liang ; LUO Li
Chinese Journal of Veterinary Science 2008;28(10):1167-1170
Canine distemper virus (CDV) neutralizing antibody (NT) titer was examined against the sera from 7 giant pandas aged between 8 to 21 years housed at Chengdu Research Base of Giant Panda Breeding,China.Anti-CDV NT titer against the Onderstepoort strain showed a wide range from × 2 to×256 (median=16),even though the ani-mals had been receiving an attenuated live vaccine made from an anonymous domestic CDV strain twice a year since 2003.A single administration of attenuated morbillivirus antigen often be enough to give corresponding host a steady immunogenicity.Anti-CDV-NT variation in the giant panda suggests some deficiency in the relationship between the vaccine and the host.
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