1.Preliminary Study on the Ecology of Trichobilharzia Cercariae in the Huaihe River System
Sichun SHENG ; Zhihui QIN ; Minqun ZHANG ; Yan TAI ; Shigang NI ; Jiyue WEN
Chinese Journal of Parasitology and Parasitic Diseases 1997;0(06):-
Objective To investigate the ecological habit and characteristics of Trichobilharzia cercariae in the Huaihe river system. Methods During June of 2002-May of 2003, Radix auricularia snails were collected monthly in Yaohe Fishery of the branch of the Huaihe River. The cercariae, released from the positive snails and collected by Shade Drop Bottle, were examined by direct press. Ducklings were infected by cercariae with different ages and examined for the infection by miracidia hatching method.Results The results showed a typical seasonal fluctuation in infection rate of the snails, i.e. the cercariae detection rate was 0.81% in July, 0.65% in June, 0.07%-0.26% in April, May, August, September and October respectively, with a significant difference (? 2=26.73, P
2.Study on effects of Lymnaeidae size on infection of Trichobil-harzia living in Huaihe River system
Sichun SHENG ; Mingqun ZHANG ; Yan TAI ; Shigang NI ; Haifeng TANG ; Zhihui QIN
Chinese Journal of Schistosomiasis Control 1989;0(03):-
F0.01(1,5)=16. 30,P0. 05). Conclusion Laboratory results thus suggest that infection intensity is related to snail size per se, whereas prevalence in the field is related to snail size only through the correlation between size and age. In addition, under these experimental conditions, infected snails were no larger than uninfected snails, so the gigantism snails observed in the field might not be attributable to Trichobilharzia-induced effect.
3. Effects of Exosomes and Their Contents on Pathogenesis and Development of Gastric Cancer
Ziqi ZHAO ; Kunming NI ; Weiwei FU ; Shigang DING
Chinese Journal of Gastroenterology 2021;26(6):373-377
Gastric cancer is a malignant tumor with worldwide high incidence and threatening the human health severely. It is a disease induced by multiple factors. Exosomes play an important role in the pathogenesis and development of many malignant tumors including gastric cancer. Exosomes can transport specific contents to regulate local and distant cell communications, and are able to promote or inhibit the development of gastric cancer through regulating the growth and proliferation of tumor cells, relevant immune function and angiogenesis of tumors. This article reviewed the effects of exosomes and their contents on the pathogenesis and development of gastric cancer.