1.The mathematical theory of acupoints.
Chinese Acupuncture & Moxibustion 2013;33(12):1094-1098
The ancient medical classics were retrieved to explore narrative on acupoints. And the relevant content of legal calendar in Shiji (Historical Records) and Hanshu (History of the Former Han Dynasty) were taken as a reference. The result showed that the total number of acu-points were based on the number of 365 days of a year. And the corrupts can be restored with the theory of numerology. The 59 heat point originated from the phase of moon, while the 57 water points originated from the number or year related with diasters. Although acupoints are considered to be related with numerology, the recognition of hot points and water points are held to be associated with experiential points in clinic.
Acupuncture
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history
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Acupuncture Points
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China
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History, Ancient
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Humans
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Mathematical Concepts
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Medicine in Literature
2.Discussion on the concerns in paediatric drug taste masking technology and evaluation
Acta Pharmaceutica Sinica 2023;58(11):3173-3178
Good palatability of pediatric drugs improves the accuracy of dosing and adherence to dosing regimens. Many active pharmaceutical ingredients have an undesirable taste, so effective taste masking methods need to be developed to improve the palatability of pediatric medicines. This article mainly introduces the commonly taste masking techniques and taste evaluation methods, and puts forward suggestions on the concerns and general principles of the pharmaceutical evaluation of taste masking effects based on cases, in order to provide reference for the development of drug taste masking technology in children.
4.Awareness rate of child health management in parents of children aged 0 - 36 months
Xiaobing FU ; Jie LIAN ; Ping SHI
Chinese Journal of General Practitioners 2012;(7):519-521
A questionnaire survey on awareness of child health management was conducted in 238 family members ( 236 were parents) of children aged 0 - 36 months; among whom 92 of children aged 0 to 6 months,85 of children aged 7 to 12 months,33 of children aged 13 to 18 months,16 of children aged 19 to 24 months and 12 of children aged 24 to 36 months.52.1% of the surveyees had college education level.The awareness about medical examination in last half year in female subjects was higher than males ( P < 0.05).There were no differences in other health management knowledge.The results showed that the average times of medical examination was 2.8 ± 1.9 in last half year; the age for supplement of meat in food was 7.4 ± 2.4 mouths; supplement of meat,animal liver and eggs was more than 7 time a week.The subjects with college education or above paid more attention to the children's growth,risk for rickets and anemia than other peoples.Pure breast feeding accounted for only 37.0% (88/238).The study indicates that strengthening the knowledge and awareness is necessary to improve the children health management.
5.Influence of Polysaccharides Removal in Modified Simiao Prescription on Anti- inflammation and Analgesic Action
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(01):-
Objective To observe the anti- inflammation and analgesic action and anti- urarthritis effect of modified Simiao prescription with polysaccharide removal and thus to screen the effective anti- gout components from modified Simiao prescription. Methods Mouse acetic- acid- induced twisting experiment, mouse xylene- induced auricular swelling experiment, and rat sodium- urate- induced pedal swelling experiment were carried out in this study. Results After the removal of polysaccharides, modified Simiao prescription still kept obvious anti- inflammation and analgesic action and in a dose- effect manner. Conclusion Polysaccharides removal has no influence on the anti- inflammation and analgesic action of modified Simiao prescription .
6.Cavins: new sights of caveolae-associated protein.
Dan SHI ; Yan LIU ; Xin LIAN ; Wei ZOU
Chinese Journal of Biotechnology 2013;29(11):1531-1537
Caveolae are specialized lipid rafts that form flask-shaped invaginations of the plasma membrane. Many researches show that caveolae are involved in cell signaling and transport. Caveolin-1 is the major coat protein essential for the formation of caveolae. Recently, several reports indicated that the other caveolae-associated proteins, Cavins, are required for caveola formation and organization. It's worth noting that Cavin-1 could cooperate with Caveolin-1 to accommodate the structural integrity and function of caveolae. Here, we reviewed that the relationship between Cavins and Caveolins and explore the role of them in regulating caveolae.
Animals
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Caveolae
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physiology
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Caveolin 1
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metabolism
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physiology
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Caveolins
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metabolism
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physiology
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Humans
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Membrane Proteins
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metabolism
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physiology
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RNA-Binding Proteins
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metabolism
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physiology
7.Preoperative immune state of gastric cancer patients
Jinghua SHI ; Teng CHEN ; Ronghua ZHAO ; Zhaorui LIAN ;
Academic Journal of Second Military Medical University 2000;0(07):-
Objective: To explore the relationship between the preoperative immune state and the progress, the prognosis in patients with gastric carcinoma. Methods: The NK cell activity (lactdehydrogenase releasing),the level of T cells subgroup (FACS) were detected preoperatively. The data of intra operative findings, pathologic observations and the results of clinical follow up were also studied. Results: The preoperative immune function in cancer patients was significantly reduced compared with the control group, and it had a significantly negative correlation with the stage of the cancer, but a positive correlation with the prognostic results. Conclusion: The detection of the preoperative immune state can play an important role in the estimation of the disease progress and the prognosis in cancer patients.
8.Analysis on implementation effect of formative assessment in nutrition and food hygiene
Wei MI ; Wu LIAN ; Tala SHI ; Weijie YI ; Wenting HAN
Chinese Journal of Medical Education Research 2014;(9):869-873
Objective To analyze the implementation effect of formative assessment in nutri-tion and food hygiene. Methods 55 students of Class One from grade 2010 majoring in preventive medicine were taken as the control group, with 56 students of Class Two as the experimental group.The control group used the summative assessment , while the experimental group used the formative assessment. Results were analyzed by course examinations and questionnaire surveys. SPSS 17.0 soft-ware was used and the measurement data were expressed by x±s. Statistical analysis was performed using t test, test, rank sum test, a Yuan linear correlation analysis, with the level of test α=0.05. Results The experimental scores and final scores of experimental group students were significantly higher than the control group and the difference was statistically significant(P values were 0.001, 0.000). The experimental group's overall result is closer to the negative skewed distribution. The ex-perimental group's average score of 89 points is significantly higher than the control group's average score of 79 points(P<0.01), and the usual results and the final results were positively correlated(r=0.865, P<0.001). The survey indicated that the students recognized the application of formative assess-ment in teaching process . Conclusion Formative assessment can help improve the teaching and learning quality in nutrition and food hygiene.
9.Biological characteristics of dendritic cells derived from peripheral blood of patients diagnosed with syphilis
Haiping ZHANG ; Wenming ZHAO ; Wei ZHU ; Shi LIAN
Chinese Journal of Dermatology 2008;41(5):304-306
Objective To study the biological characteristics of dendritic cells (DCs) derived from peripheral blood mononuclear cells (PBMCs) of patients diagnosed with syphilis. Methods PBMCs were isolated from 16 patients clinically and serologically diagnosed with syphilis, and from 16 healthy human controls, then cultured with GM-CSF and IL-4. On day 10, the monocyte-derived dendritic cells (MoDCs)of the patients and controls were collected and subjected to the detection of surface molecules by flow cytometry; TpN17 was used to stimulate MoDCs from the controls, the expression of phosphorylated ERK was detected by Westem blotting 20 minutes following the stimulation. Results The positivity rate of CD80 was significantly increased in the patients with syphilis than that in the controls (51.90% vs 33.67,P < 0.05), while no significant difference was observed in the expressions of CD83, CD86 or HLA-DR be tween the two groups (16.53% vs 15.99%, 66.13% vs 59.32%, 91.29% vs 90.51%, all P 0.05). The ex pressions of CD80 and CD83 on the surface of MoDCs were enhanced in a dose-dependent manner after ex-posure to TpN17. The expression of cytoplasmic phosphorylated ERK was observed in MoDC stimulated by TpN17, but not in those without the treatment. Conclusions Antigenic stimulation with Treponema pal-lidum may be a reason for phenotypic abnormality of MoDCs derived from patients with syphilis. TpN17 may stimulate the maturation of DCs through the ERK signal transduction pathway.
10.MRI Manifestations of the Dural Sinus Thrombosis
Junling XU ; Dapeng SHI ; Xiaoming MAO ; Jianmin LIAN ; Shewei DOU
Journal of Practical Radiology 2001;0(05):-
Objective To sum up MRI and MR venography features of the dural sinus thrombosis (DST).Methods The findings of MRI and MR venography in 20 patients with DST were retrospectively analysed.Results MRI showed the normal flowing void of the dural sinus disappeared,instead of the abnormal high signal intensities.The easily involved positions respectively were transversal - sigmoid, superior sagittal and straight sinuses. Some cortical drainage and large internal cerebral veins were also involved . MR venography demonstrated that there were no blood flowing in these involved dural sinuses or veins . The locations of these lesions in MRI were same as that in MRV.Conclusion Because the DST can be directly displayed in MRI and MR venography,they are the most reliable methods of non- invasive diagnosis of DST.