Objective To explore the significance of calcification in diagnosis of thyroid mass , and to improve the differential diagnosis of benign and malignant thyroid nodules .Methods 286 cases with thyroid masses admitted to the hospital from Jan .2008 to Dec.2012 underwent preoperative ultrasound scan .The clinical data were retrospectively analyzed from patients with or without calcification , the characteristics of different calci-fication and the comparison between preoperative diagnosis and postoperative pathological results .Results Ultra-sound and pathological analysis showed there was significant difference between calcification group and non -calci-fication group in detection rate of thyroid cancer (66.98%vs 13.51%, P<0.05).Detection rate of thyroid car-cinoma was significantly higher in microcalcification group than in coarse calcification group ( 84.42% vs 20.69%,P<0.05) .There was significant difference in detection rate of benign and malignant nodules in the two types of calcification group(P<0.05).The detection rate was higher in the malignant nodules than in the benign nodules .The detection rate of thyroid cancer had no statistical significance in non-calcification group and coarse calcification group ( P>0.05 ) .Conclusion Thyroid calcification , especially microcalcification has important significance in diagnosis of thyroid cancer .

Objective To explore the diagnostic value of multiplanar reconstruction(MPR)of spiral CT in the disorders of lumbar intervertebral discs.Methods Fourty-one cases with the disorders of lumbar intervertebral discs were examined with conventional CT scans and MPR of spiral CT.CT findings of intervertebral discs at L 3/4 ,L 4/5 and L 5/S 1 were compared and observed.Results The conventional scans showed bulging and /or herniation of intervertebral discs in 35 cases,and normal in 6 cases which compression of nerveroots by intervertebral discs or osseous narrow of intervertebral discs were showed on MPR.The MPR showed compression of nerve roots,compression of dural sac or osseous narrow of intervertebral foramens in 36 cases.Conclusion MPR possesses important value in diagnosing the disorders of lumbar intervertebral discs,showing the causes of lumbar vertebral diseases and distinguishing the various diseases of lumbar vertebrae.

This review summarizes the present situation of research, development and application of the Chinese herbal feed additives and its prospect. It can provide scientific references for researchers to carry out in-depth study. Chinese herbal feed additives will hopefully solve problems such as antibiotic residues, environmental pollu-tion, low productivity which hinders the development of livestock and provides strong support for developing green husbandry, meeting the food safety demand, closing the gap of livestock between the developed countries and Chi-na, increasing competitiveness of Chinese animal products in world markets. The development of Chinese herbal feed additives have very important economic and social benefits.

Angelica ; chemistry ; Animals ; Animals, Newborn ; Cell Count ; Female ; Fetal Hypoxia ; pathology ; Hippocampus ; cytology ; drug effects ; Male ; Neuroglia ; cytology ; Neurons ; cytology ; Pregnancy ; Rats ; Rats, Sprague-Dawley

Accidents, Occupational ; Adult ; Female ; Humans ; Male ; Nitrogen Mustard Compounds ; poisoning ; Occupational Exposure ; adverse effects

Objective: To investigate the gene expression of bone morphogenetic protein(BMP)in human cervical disc.Methods:cervical disc specimen were obtained from patients undergoing anterior disc surgery,who had the signs of cervical disc herniation.Immunohistochemical and in situ hybridization studies were conducted to detect cells with BMP gene expression.Results:It showed positive staining of BMP-like immunohistoreactivity and its mRNA gene expression in degenerated discs,osteophytes,posterior longitudinal ligments,amd periosteum of vertebra.Conclusion:BMP may be relate to intervertebral disc degeneration as prolifertion-stimulating factor of chondrocytes that replace normal anular cells during disc degeneration but its mechanism needs further study.

AIM: To evaluate posterior capsular opacification (PCO) with hydrophobic acrylic intraocular lens (IOL, Sensar AR40e) and silicone IOLs after cataract surgery, to use a software program developed to provide an objective assessment of the amount of PCO in the digital images of the posterior capsule to quantify PCO. METHODS: Ninety-eight eyes underwent standardized phacoemulsification and "in the bag" IOL placement, were randomized to receive a three piece lens of hydrophobic acrylic or silicone, but lens materials were different in one case. In year 1 and 2, digitized retro-illumination images were taken from the posterior capsule. Images were analyzed by POCO software program, removing the Purkinje light reflexes, contrast enhancement, filtering to enhance low-density PCO. RESULTS: The percentage of PCO were 0.32±0.13 of hydrophobic acrylic IOLs in year 1, compared with 0.39±0.17 of silicone (P=0.37). In year 2, the percentage of PCO were 0.42±0.20 with hydrophobic acrylic IOLs and 0.34±0.18 with silicone IOLs (P=0.50). Of those patients with PCO in year 1 and 2, severity grades were 0.50±0.30 and 0.82±0.58 of hydrophobic acrylic cases, compared with 0.63±0.35 and 0.55±0.35 of patients with silicone IOLs (P=0.52,P=0.69) with no statistical significance.CONCLUSION: The POCO system is capable of producing an objective and repeatable measure of PCO that is relevant to assessing techniques of PCO prevention.

Objective:To investigate the effect of PBL+LBL double-track in long-term-system clinical medicine in Gynecology and Obstetrics.Methods:We divided the students of 2001-seven-year-progrems in random into two groups: trial group practiced PBL+LBL double-track teaching,control group practiced LBL teaching.Results The results showed that although the two groups had no significant difference in examinational total score and in foundational subjects,but the trial group had a significant higher score in comprehend subjects.The students exhibited great enthusiasm to the PBL.And the students learned and absorbed more knowledge of gynecology and obstetrics and literature retrieval.The education method played a comprehensive functional role for the teacher-directed and student-oriented tutorial process,and the teaching effects improved.Meanwhile,the teachers need to be prepared with more knowledge to meet the students query.Conclusions:PBL+LBL double-track teaching method can improve the students'activeness and can culture their ability of self-study;and at the same time the new teaching method can remain the systematicness,profundity and extent of knowledge.It is a better way in clinical education,and is well accepted by both students and teachers as it can greatly improve teaching efficacy.

Objective To investigate the resistance rate of Helicobacter pylori (Hp) to clarithromycin and its correlation with point mutations in 23S rRNA gene. Methods Hp was cultured from gastric biopsy specimen obtained from 189 patients undergoing upper gastrointestinal endoscopy. The DNA of 11 clarithromycin sensitive Hp and 19 clarithromycin resistant Hp was extracted, and 23S rRNA was amplified and sequenced. Results The rate of clarithromycin resistance in cultured Hp was 29. 2%. Point mutations in 23S rRNA gene were found in 17 clarithromycin resistant Hp strains. The proportion of A to G mutation was 36.8%, G to A of 21.5%, C to T of 15.8%, A to C of 10.5% and T to C of 5.3%. No point mutation in 23S rRNA was detected in other 2 clarithromycin resistant and 11 sensitive Hp strains. Conclusion The resistance to clarithromycin is common in Hp, and point mutations in 23S rRNA gene of Hp are frequent in clarithromycin resistant strains, with most prevalent mutations of A to G and next G to A.

Objective: To develop a grinding intrument for removing the remaining bonding material and polishing the dental enamel after orthodontic treatment. Methods: A dental griding instrument was made based on ultrasonic principle with the frequency of 25～45 kHz. 60 premolars extracted for orthodontic purpose were used in the experiment, before treatment the surface roughness was measured and recorded as Ra 1. Brackets were adhered to the premolars, and then debonded. The surface enamel of 30 teeth were polished by the ultrasonic grinding instrument (group of GI), that of another 30 by conventional technique(group of CT) , the roughness was measured and recorded as Ra 2. Results: In group GI Ra 1 and Ra 2 were 0.846 6?0.428 2 and 0.740 5?0.372 1(P0.05), respectively. After treatment Ra 2 in group GI was smaller than that in group CT(P