1.Research on the Students′Socialist Core Values Construction in Medical University
Xiaoning LU ; Wenyan XI ; Shengyu FU
Chinese Medical Ethics 2016;29(5):795-797
Objective:To investigate the cognitive status of socialist core value among medical students, and to provide reference for the core value education in medical colleges and universities. Methods: 1024 medical students were selected with random cluster sampling method, and the socialist core value was investigated using self-designed questionnaire. Results:It was shown that 69 percent of medical students recognized the importance of socialist core values, but the contents had not been mastered. Social atmosphere, medical student's own short-coming and school education were all the factors leading to the weakness of socialist core values. Conclusion:It is quite necessary to cultivate medical students′socialist core values. Class, school, and society should play the main role to guide the medical students to establish the correct socialist core value.
2.Clinical analysis for 66 cases of brucellosis in a general hospital
Ying GE ; Xiaoqing LIU ; Shengyu ZHANG ; Jie LU ; Guohua DENG
Chinese Journal of General Practitioners 2011;10(6):420-422
Epidemiological, clinical, laboratory and treatment data, as well as outcomes of 66patients diagnosed as brucellosis during 1984 to 2010 in Peking Union Medical College Hospital were retrospectively analyzed. Thirty-four (51.5%) patients had a history of close contact with sheep or cows infected with brucellosis, eight (12. 1% ) had eaten not-fully-boiled or roasted mutton, three (4. 5% ) had drunk or contacted with contaminated milk, and transmission route was unknown in 21 (31.8%). The most common manifestations were fever ( 97.0%, 64/66 ), loss of appetite and fatigue ( 93. 9%, 62/66 ),sweating (47.0%, 31/66), myalgia and arthralgia (54. 5%, 34/66 ), hepatomegaly (27.3%, 18/66),splenomegaly (37.9%, 25/66), increased erythrocyte sedimentation rate (ESR) (62. 1%, 41/66), and elevated C-reactive protein (65.4%, 34/52). Average interval from onset to diagnosis was 19. 2 weeks. All 66 patients were positive in serum agglutination test for BruceUa, and 28 (42. 4% ) positive in blood or bone marrow culture for Brucella. Sixty-five of 66 patients were treated by standard combined treatment with rifampicin, quinolone, minocycline and streptomycin, with all effective, and only four with mild liver damage in treatment who got better after discontinuing medicines and changing treatment regimen.
3.Investigation on Medical Students' Ethical Cognition of Assisted Reproductive Technology
Xiaoning LU ; Wenyan XI ; Shengyu FU ; Xianghong LI ; Qiang HAN
Chinese Medical Ethics 2017;30(8):985-988
Objective:To investigate the medical students' cognition of ethical issues in assisted reproductive technology (ART) and discuss the importance of ethical education in medical colleges and universities.Methods:A questionnaire survey about the ethical cognition of assisted reproductive technology was conducted among 632 medical students.The questionnaire included the donation and management of gametes and embryos,and offspring problems.Results:Medical students agreed with most of the current ART-related laws and regulations.however,44.8% of medical students considered that criteria of donating eggs should be relaxed,such as allowing women who do not receive ART treatment be paid for eggs.In addition,a total of 39.0% of medical students supported the legalization of surrogacy technology in china.Conclusion:Medical students exists a certain misunderstanding in egg donation and surrogacy technology.We should give more training to medical students in ethical knowledge.In addition,our country can supplement and perfect the current laws and regulations to a certain extent.
4.Preparation and Certification of Reference Materials for 3-Amino-2-oxazolidinone Residue in Eel Muscle Lyophilisates
Fang YANG ; Shoushen YANG ; Shengyu LU ; Zhengcai LIU ; Kongjie YU ; Yaoping LI ; Xiaogang CHU
Chinese Journal of Analytical Chemistry 2010;38(3):397-400
A methodology for preparing and certifying the reference material of 3-amino-2-oxazolidinone(AOZ) in eel muscle lyophilisates was presented. Furazolidone was accessed to eel by dipping fish in pond with furazolidone solution at a dosage of ca 0.16 mg/L. With the metabolism of furazolidone in eel, the muscles contain a certain concentration of AOZ as furazolidone metabolite was obtained. Lyophilization of the muscles was performed in one batch and 400 bags of samples were obtained by the procedure of homogenation, cryodesiccation and irradiation. The homogeneity and stability of the sample was examined. The value of the chemical constituent of the sample was certified through the collaborative analysis program participated by 11 laboratories using isotope dilution liquid chromatography-tandem mass spectrometry, and the uncertainty assessment was performed. The reference materials have been approved as certified reference materials by AQSIQ, China (State General Administration of the People′s Republic of China for Quality Supervision and Inspection and Quarantine) in 2009 after one year of trial period. The serial numbers is GBW(E)100180.
5.Eye Movement Characteristics of Cooperation Degree during Image Completion Test in Psychiatric Impairment Assessment
Junjie WANG ; Chao LIU ; Lu LIU ; Shengyu ZHANG ; Haozhe LI ; Weixiong CAI
Journal of Forensic Medicine 2017;33(2):154-157,161
Objective T o explore the difference of eye m ovem ent characteristics betw een uncooperative and cooperative subjects w ith m ental disorder after cerebral traum a. Methods T hirty-nine subjects w hich needed psychiatric im pairm ent assessm ent w ere selected. A ccording to the binom ial forced-choice digit m em ory test (BFD M T),allsubjects w ere divided into cooperative and uncooperative groups. The subjects w ere asked to take the im age com pletion test from W echsler adult intelligence scale. M eanw hile, the data of eye m ovem ent track, fixation, saccade, pupil and blink w ere recorded by the track system of eye m ovem ent. Results T here w ere significantly differences (P<0.05) in the data of saccade betw een coopera-tive (10 cases) and uncooperative groups (29 cases). T he frequency, tim e, am plitude, acceleration of saccadic in uncooperative group w ere significantly higher than cooperation group. T he saccade latencies of cooperation group increased m ore than uncooperative group. T here w as a significant difference (P<0.05) in total discrete distance, average distance and total tim e of fixation betw een tw o groups, w hile the aver-age duration tim e, num ber and frequency of fixation had no significantly difference (P>0.05) betw een tw o groups. A nd the blink frequency of cooperation group w as higher than uncooperative group. Conclusion E ye m ovem ent can be an objective index for the prim ary judgm ent of cooperation level.
6.The MRI and clinical features of acinic cell carcinoma of the parotid gland.
Xinping KUAI ; Shengyu WANG ; Guorun FAN ; Qingguo DING ; Hongbo ZHAO ; Chuanhai JIA ; Yongming LU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(24):1968-1971
OBJECTIVE:
To analyze the MR imaging findins of acinic cell carcinoma(ACC) in parotid gland and develop the diagnosis of this disease.
METHOD:
The MR imaging fearures of 11 patients with pathologically proved ACC were retrospectively analyzed. MR imagings were analyzed in relation to the follow:amount, location, size, shape, margin, pseudocapsule, MR signal intensity and enhanced pattern and the cervical lymphadenopathy. The clinical analysis on patients included age, sex, and follow-up.
RESULT:
There were 11 patients, 7 lesions was located in the right parotid gland and 4 lesions was located in the left parotid gland; the average maximum diameter was (2.66±0.99)cm; 7 lesions showed lobulated,and 4 lesions showed round; 8 lesions had no pseudocapsules and 3 lesions had incomplete pseudocapsule. All lesions showed homogeneous or heterogeneous isointense and slight hyperintense on T1 WI and T2WI. On post contrast images, the tumor parenchyma ingredients showed remarkable enhancement in all lesions.
CONCLUSION
The MR imaging of ACC in the parotid gland don't have specific features, but when the tumor of the parotid gland showed no pseudocapsule (or showed incomplete pseudocapsule), lobulate, small cysitc and remarkable enhancement, it may indicate ACC, and the correct diagnosis depends on clinical pathology.
Carcinoma, Acinar Cell
;
pathology
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Contrast Media
;
Humans
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Magnetic Resonance Imaging
;
Parotid Gland
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Retrospective Studies
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Salivary Gland Neoplasms
;
pathology
7.Genetic analysis of an infant with duplication 9q34 syndrome.
Yu TONG ; Shengyu YAN ; Jianyou SHI ; Lu CHEN ; Cheng WAN ; Kai XU
Chinese Journal of Medical Genetics 2018;35(3):437-439
OBJECTIVETo determine the genetic cause of an infant with multiple congenital anomalies.
METHODSRoutine karyotype analysis and chromosome microarray analysis (CMA) were carried out for the infant and her parents.
RESULTSCMA has detected a 9.3 Mb duplication at 9q34.11-q34.3. G-banding analysis suggested that the infant has a 46,XX,der(1)add(1)(p34.1) karyotype, while her father was 46, XY, t(1,9)(p36.3;q34.1). Fluorescence in situ hybridization (FISH) analysis confirmed that the 9q34 duplication has derived from the balanced translocation carried by the father.
CONCLUSIONA 9.3 Mb duplication was detected within the 9q34 region in an infant featuring multiple congenital anomalies. CMA and FISH have enabled detection of this duplication and facilitated genetic counseling and prevention of birth of further affected offspring.
8.Establishment and application effects of a homogenized teaching model for ICU nursing students
Xiaochun LIU ; Shengyu HUANG ; Mingming WANG ; Yu LU
Chinese Journal of Modern Nursing 2017;23(12):1687-1690
Objective To explore a homogenized teaching model for ICU nursing students, and to discuss its effects when applied in clinical nursing teaching.Methods To establish a homogenized teaching model for ICU nursing students, totally 56 college nursing students studying in the ICU of a tertiary hospital between May 2015 and April 2016 were investigated as a treatment group who received homogenized teaching; and some nursing students practicing in the same ICU from May 2014 to April 2015 received traditional teaching as a control group. Their regular performance, theoretical examination and operation test scores were then compared, and clinical teachers and nurses′ comments on the homogenized teaching model were investigated, too.Results The scores of nursing students in the treatment group for regular performance, professional theory, professional operation and nursing rounds were (19.20±4.02), (28.6±3.34), (28.4±4.45) and (18.70±4.00), respectively, all higher than the figures of nursing students in the control group (P<0.05), which were (15.9±2.97), (24.8±3.88), (24.2±3.49) and (15.2±3.22), respectively; and nursing students in the treatment group had higher evaluation on teaching effects, including teaching objectives, contents, methods, positivity and comprehensive capacity building, than nursing students in the control group (P<0.05). Conclusions The homogenized teaching model, when applied in teaching college nursing students, helps them understand ICU expertise, improves clinical teaching effects, avoids randomized traditional teaching, and enhances homogenized management of clinical teaching for ICU nursing students.
9. Lymphomatoid gastropathy: one case report and literatures review
Yangzhong ZHOU ; Yan ZHANG ; Weiyang ZHEN ; Shengyu ZHANG ; Jian SUN ; Zhaohui LU ; Wei ZHANG ; Daobin ZHOU ; Tienan ZHU
Chinese Journal of Hematology 2018;39(11):937-941
Objective:
To report the first case of lymphomatoid gastropathy in China, and to demonstrate the clinical characteristics, diagnostic approach, treatment and prognosis in this kind of patients.
Methods:
One patient was diagnosed as lymphomatoid gastropathy at Peking Union Medical College Hospital, and her clinical characteristics, lab data, treatment and follow-up outcomes were reviewed.
Results:
A case of a 51-year-old female was presented, who underwent esophagogastroduodenoscopy (EGD) due to slight epigastric discomfort. EGD revealed multiple ulcers and erosions. Biopsies showed atypical lymphocytes infiltration with CD3(+), CD56(+), CD20(-), CD8(-), TIA(+), Granzyme B(-) and Ki-67 (75%). Epstein-Barr virus-encoded RNA in situ hybridization was negative. Four months later, repeated EGD examination showed regression of the lesions without specific treatment.
Conclusion
Lymphomatoid gastropathy was a unique disease entity mimicking NK/T-cell lymphomas in pathology, with the quite different profile of treatment and prognosis. It’s important to consider this issue during the differential diagnosis to avoid any excessive treatment.
10.The acceleration algorithm for projection decomposition of dual-energy computed tomography image reconstruction based on projection matching.
Xiaowen HOU ; Zipeng LU ; Yueyang TENG ; Dayu XIAO ; Shengyu FAN ; Chaoran YANG ; Yujia LIU ; Yan KANG
Journal of Biomedical Engineering 2018;35(3):376-383
Dual-energy computed tomography (CT) reconstruction imaging technology is an important development direction in the field of CT imaging. The mainstream model of dual-energy CT reconstruction algorithm is the basis material decomposition model, and the projection decomposition is the crucial technique. The projection decomposition algorithm based on projection matching was a general method. With establishing the energy spectrum lookup table, we can obtain the stable solution by the least squares matching method. But the computation cost will increase dramatically when size of lookup table enlarges and it will slow down the computer. In this paper, an acceleration algorithm based on projection matching is proposed. The proposed algorithm makes use of linear equations and plane equations to fit the lookup table data, so that the projection value of the decomposition coefficients can be calculated quickly. As the result of simulation experiment, the acceleration algorithm can greatly shorten the running time of the program to get the stable and correct solution.