1.Analysis of prognosis and risk factors of patients with bronchopulmonary carcinoid tumors after surgical treatment
Feng TANG ; Shengjun TANG ; Xiaolong GUO ; Shu XIANG ; Chao YANG
Chongqing Medicine 2014;(22):2870-2872
Objective To investigate the prognostic factors and survival of patients with bronchopulmonary carcinoid tumors (BPC) after surgical treatment .Methods The clinical data of 87 patients undergoing surgery for BPC from Jan .2002 to Dec .2008 were reviewed retrospectively .Kaplan-Meier method was used to analyze the survival of the patients .The risk factors such as age , gender ,smoking history ,histological type ,tumor size ,were analyzed by Cox proportional hazards regression model .Results The 1-,3-and 5-year overall survival rates were 85 .1% ,71 .3% and 63 .2% .Univariate analysis revealed that age (P=0 .016) ,smoking history(P=0 .007) ,histological type(P=0 .000) ,tumor stage(P= 0 .000) ,tumor size(P= 0 .006) lymph node metastasis(P=0 .000) ,surgery type (P= 0 .045) and postoperative chemotherapy (P= 0 .000) were prognostic factors .Multivariate analysis showed that histological type(P=0 .008) ,tumor stage(P=0 .000) ,lymph node metastasis(P=0 .033) were independent prognostic factor .Conclusion The survival rate of the BPC patient after surgical treatment is high ,histological type ,tumor stage and lymph node metastasis were independent prognostic factors .
2.Analysis on correlation between SIRS occurrence and calculi composition after flexible ureteroscopy lithotripsy
Li JIANG ; Shengjun LUO ; Lei YANG ; Wei TANG
Chongqing Medicine 2017;46(25):3489-3490,3493
Objective To analyze the correlation between postoperative systemic inflammatory response syndrome (SIRS) and calculi composition following flexible ureteroscopy (f-URS) lithotripsy.Methods The clinical data of 1 130 patients with kidney stones treated with f-URS lithotripsy in the department of urology surgery of our hospital from November 2013 to August 2016 were collected to analyze the correlation between postoperative SIRS occurrence and calculi composition.Results The compositions of urinary stones were mainly calcium oxalate monohydrate(67.7 %),carbonate apatite (14.7 %),anhydrous uric acid (6.4 %),six magnesium ammonium phosphate (6.2 %) and calcium oxalate dihydrate (3.2 %).Only six magnesium ammonium phosphate was related to the development of SIRS(P<0.01).Conclusion Six magnesium ammonium phosphate has a correlation with the development of SIRS following f-URS lithotripsy,and the results of stone compositions analysis can help to prevent the occurrence of SIRS after f-URS lithotripsy.
3.Diagnosis and treatment of insulinoma:a report of 30 cases
Wei WEI ; Huihuan TANG ; Shengjun HUO ; Jushi LI
Chinese Journal of General Surgery 1993;0(03):-
Objective To discuss the diagnosis and treatment of insulinoma.Methods The clinical data of 30 patients with insulinoma were reviewed.Results All patients had Whipple′s triad.Accurate preoperative localization rate of B ultrasonography, CT and MRI was 34.8 %(8/23),58.3 %(7/12) and 71.4 %(5/7),respectively. Localization rate of intraoperative ultrasonography (IOUS) was 87.5 %(7/8). The tumors were single in 27 cases,and multiple in 3 cases. In the location of single tumor,8 of them were in the head,7 in the body, and 12 in the tail; while for multiple tumors, 2 tumors were both located in the body in 1 patient,and 2 tumors were separately located in the body and tail respectively in 2 patients. Local enucleation was performed in 21 cases, distal pancreatectomy in 6 cases,distal pancreatectomy plus splenectomy in 2 cases,and duodenopancreatectomy in 1 case. The tumor was benign in 29 cases, and malignant in 1 case.Pancreatic fistula developed after operation in 4 cases, and in all cases, it healed after drainage. All patients had no symptoms of hypoglycemia after operation. At follow-up visit in 27 cases, 1 case of benign tumor recurred 4 years after operation, and was cured by resection of the pancreas body with tumor; the malignant tumor case, recurred and died of metastasis of abdominal cavity 3 years after operation.Conclusions Whipple′s triad, and the ratio of immunoreactive insulin to blood glucose (IRI/G)are the bases for qualitative diagnosis of insulinoma. Meticulously palpating the gland combined with IOUS during operation is the most effective method for accurate tumor localization. Enucleation is the main mode of surgical treatment of insulinoma.
4.Relationship between schizotypal personality proneness and intelligence
Junhua TANG ; Shengjun WU ; Xufeng LIU ; Yebing YANG ; Jianquan TIAN ; Jingjing TANG ; Chao HE ; Danmin MIAO
Chinese Journal of Behavioral Medicine and Brain Science 2010;19(2):130-132
Objective To explore the relationship between schizotypal personality proneness and intelligence .Methods 1905 subjects were tested by Chinese Soldier Personality Questionnaire(CSPQ).According to the results of CSPQ,the subjects were divided into high-risk subjects and normal ones.The Words Reasoning Test, the Arithmetic Reasoning Test and the Assembling Test were used to evaluate the intelligence,and the scores of these tests were compared between the two groups.Correlation coefficient between schizotypal personality proneness and intelligence was calculated.Results The scores of the Words Reasoning Test,the Arithmetic Reasoning Test and the Assembling Test in high-risk subjects were significantly lower than those in normal ones((87.83±18.42)VS(101.37±13.48),P<0.01;(91.74±14.26)vs(101.65±14.62),P<0.01;(87.70±18.82)VS (101.73±14.26),P<0.01).Schizotypal personality proneness was significantly correlated with the scores of intelligence(r=-0.39,P<0.01).Conclusion Lower intelligence level is found in the group with schizotypal personality proneness.Intelligence is correlated with schizotypal personality proneness.
5.Value of diagnosis with the 256-slice spiral CT in severe tetralogy of Fallot of infant
Mingfeng DONG ; Zengshan MA ; Shengjun MA ; Jiantang WANG ; Shoudong CHAI ; Peizhe TANG
Chinese Journal of Postgraduates of Medicine 2011;34(30):31-33
ObjectiveTo approach the value of diagnosis with the 256-slice spiral CT in severe tetralogy of Fallot of infant.MethodsFrom January 2008 to December 2010,48 cases (severe tetralogy of Fallot of infant) were examined with 256-slice spiral CT preoperatively.All cases were then analyzed in workspace with maximum intensity projection(MIP),multiplanar reconstruction(MPR) and volume rendering (VR),while compared with transthoracic echocardiography (TTE) and surgical results.Results CT examination found that TTE misdiagnosis 4 cases of patent ductus arteriosus and 6 cases of aortic coarctation.Meanwhile,CT showed 6 aorta pulmonary collateral arteries in 5 cases.In 48 cases,surgical results confirmed 47 cases by 256-shce spiral CT,while 33 cases by TTE.The diagnosis accuracy rate of 256-slice spiral CT and TTE was 97.9% (47/48) and 68.8% (33/48) respectively.There was statistically significant difference of the two inspections in diagnostic accuracy (P < 0.05).ConclusionThe inspection of 256-slice spiral CT can benefit the preoperative diagnosis and operation program in severe tetralogy of Fallot of infant.
6.Study on Curing Time Controlling of Materials Based on Isocyanate and Its Application in Transmitting Apparatus for the Wounded
Tiebing LIU ; Liming TANG ; Zheng WANG ; Shengjun LIU ; Min WU ; Shitao QI ; Xingxi ZHU ; Chao ZHANG
Chinese Medical Equipment Journal 2009;30(7):21-24
Obiective To study controUing method for curing time of the materials based on isocyanate, and perfect making means and operating rules of transmitting apparatus for the wounded, Methods According to the controlling principles of the rate of chemical reaction, the influencing factors' were studied such as catalyzer, ambient temperature, mixture level of materials and materials volume by experiment. Results By the results of experiments, ambient temperature hasn't an effector impact on eufing time of isocyanate, catalyzer and mixture level of materials only have a little effect or impact on initial reaction time, but materials volume is an important factor of all. Conclusion By the means of experiments, the curing time of isocyanate is only influenced by the volume of materials, and the character is very useful to transmitting apparatus for the wounded in field battle or on-site emergency rescue.
7.Analysis of psychological status and influencing factors of medical workers amid COVID-19 pandemic; analysis of influencing factors
Xufeng LIU ; Yifei WANG ; Kang SHI ; Gang CHEN ; Shiqi TANG ; Yongqi LI ; Jingkuan SU ; Shengjun WU ; Qiang ZENG
Chinese Journal of Health Management 2021;15(2):167-172
Objective:The study seeks to explore the factors influencing the psychological status and sleep quality of medical workers amid the ongoing COVID-19 pandemic, in order to provide data sources and theoretical basis for the development of relevant psychological intervention programs.Methods:Employing the convenience sampling method, general information questionnaire (age, gender, marital status, educational background, job status, etc.), Generalized Anxiety Disorder-7 and Patient Health Questionnaire, epidemic stress index scale, and sleep quality questionnaire were distributed to medical staff between February 18 and April 3, 2020, using the PEM mental health care platform of by ZhongShengKaiXin for medical staff issued. Descriptive, single factor, and correlation analyses, as well as multiple linear regression analysis were used to analyze the data.Results:Overall, 24, 845 questionnaires were collected from 23 provinces, of which 24, 687 were valid, with a recovery rate of 99.36%. The findings showed that the proportion of medical personnel with symptoms of anxiety and depression was 50.58% and 51.37%, respectively; 16.11% had poor or very poor anti-stress ability; and 71.78% reported poor or very poor sleep quality. There was a positive correlation between anxiety, depression, anti-stress ability, and sleep quality ( P<0.05). Anxiety was positively correlated with depression, stress tolerance, and sleep quality( r=0.787, 0.667, and 0.486, all P<0.001); depression was positively correlated with stress tolerance and sleep quality ( r=0.709 and 0.586, both P<0.001); and stress tolerance was positively correlated with sleep quality ( r=0.452, P<0.001). Multiple linear regression analysis results showed that age, gender, marital status, educational background, professional title, job status, and participation influenced the anxiety levels of medical personnel in the backdrop of the pandemic ( P<0.001). Depression levels of medical staff were influenced by gender, educational background, job position, and participation ( P<0.001), while gender, marital status, educational background, job position, and participation influenced the stress tolerance levels ( P<0.001). The sleep quality of medical workers was influenced by age, gender, job position, participation in the fight against the pandemic, and professional title ( P<0.001). Conclusions:Amid the ongoing COVID-19 pandemic, medical staff reported poor mental health status and sleep quality, which can be attributed to diverse factors. The research findings can be useful for assisting medical staff to strengthen their self-cognition, while also providing certain psychological counseling data and theoretical basis for management departments.
8.Reasons and treatment methods of high transprothetic pressure gradient after aortic valve replacement
Jindong LI ; Yanhong WU ; Mingfeng DONG ; Jiantang WANG ; Shoudong CHAI ; Peizhe TANG ; Tao LIU ; Zhenkun LI ; Feng XIA ; Shengjun MA
Chinese Journal of Postgraduates of Medicine 2016;39(10):883-885,886
Objective To analyze the reasons and treatment methods of high transprothetic pressure gradient after aortic valve replacement. Methods The clinical data of 45 patients with high transprothetic pressure gradient after aortic valve replacement were retrospectively analyzed. The patients were followed up for average 24.6 (12 - 40) months. The postoperative effective orifice area (EOA) of artificial valve was measured by transthoracic color Doppler ultrasound. Compared with published referred EOA of different artificial valve, there were 2 kinds results:measured EOA=referred EOA and measured EOA
9.H. L.P.E.S. scoring system combined with a virtual reality technique for evaluation of the stone-free rate of flexible ureteroscopy in the treatment of renal calculi
Jianglin GU ; Shengjun LUO ; Li JIANG ; Daixing HU ; Guozhi ZHAO ; Wei TANG
Chinese Journal of Urology 2022;43(5):384-386
The clinical data of 120 patients admitted to our hospital with renal stones treated by flexible ureteroscopy (FURS) and the imaging-related data measured by virtual reality technology were retrospectively analysed. The results of the univariate analysis showed that stone surface area (S), renal pelvis volume (P), length of calyces funnel (L), pelvic calyceal height (H) and essence of stone (E) were closely related to stone-free rate. The H. L.P.E.S. score was constructed to predict stone-free rate after FURS based on the above factors, and the area under the receiver aperating characteristic curve for the H. L.P.E.S. and S. O.L.V.E. scoring systems was 0.921 and 0.754 respectively.The H. L.P.E.S. scoring system has higher predictive value.
10.Evaluation the clinical value of S.O.L.V.E.nephrolithometry scoring system for predicting the stone-free rate of flexible ureteroscopy
Shengjun LUO ; Hao HU ; Daixing HU ; Guozhi ZHAO ; Lifeng GONG ; Wei TANG
Chinese Journal of Urology 2018;39(9):661-666
Objective To establish S.O.L.V.E.nephrolithometry scoring system,and to evaluate value of S.O.L.V.E.scoring system for predicting the stone-free rate (SFR) of flexible ureteroscopy (FURS).Methods Five reproducible variables were included in S.O.L.V.E.scoring system,such as stone surface area (S),obstruction (O),length of calyces funnel (L),visible number of calyces (V) and essence of stone (E).Variables were measured based on preoperative non-contrast computed tomography of urography.Clinical data of 392 patients who underwent FURS for upper urinary tract stones in our department from January,2017 to Jnne,2018 were retrospectively analyzed.The total study population consisted of 258 male and 134 female patients.The mean age was (49.5 ± 12.6) years old,ranged from 15 to 85 years.There were 292 patients in stone-fiee group,including 197 male and 95 female patients.The average age was (49.2 ± 12.8) years old.37 patients had previous history of renal stone surgery.Median body mass index was 24.7 kg/m2 (18.1-29.0 kg/m2) and median value of preoperative serum creatinine was 72.5 μmol/L (48.9-84.8 μmol/L).The number of patients,whose stone located in the left side and right side were 155 and 137,respectively.The number of patients,whose stones located in ureter,renal pelvis,lower calyceal and non-lower calyceal were 19,16,87,170,respectively.There were 100 patients in non-stone free group,61 men and 39 women.The average age was (50.4 ± 12.0) years old.15 patients had previous history of renal stone surgery.Median body mass index was 25.0 kg/m2 (18.5-28.8 kg/m2) and median value of preoperative serum creatinine was 73.8 μmol/L (46.5-92.5 μnol/L).The number of patients,whose stone located in the left side and right side were 51 and 49,respectively.The number of patients,whose stones located in ureter,renal pelvis,lower calyceal and non-lower calyceal were 7,4,27,62,respectively.The correlation of S.O.L.V.E.scoring system and stone-free rate,postoperative hospital stay,surgical complications,operation time were analyzed.Receiver operating characteristic curves were drawn to detect predictive value of S.O.L.V.E.scoring system for SFR of FURS.Results All cases FURS were performed successfully and the SFR was 74.5% (292/392).Among the variables of the S.O.L.V.E.scoring system in the stone-free group and the non-stone free group,item S were (82.6 ± 69.8) mm2 and (172.6±133.7)mm2,respectively.The item L were (12.7 ± 15.8) mm and (23.9 ± 15.3)mm,respectively.The item V were (0.6 ± 0.7) and (1.3 ± 0.8),respectively.The item E were (817.1 ± 285.5) HU and (902.4 ± 256.1) HU,respectively.The difference was statistically significant (P < 0.01).The item O was (17.7 ± 10.9) mm and (19.3 ± 13.1) mm,respectively,no statistical significance was found (P =0.242).The mean score was 6.3 (ranging 4-11) in this c ohort.The patients were divided into low score (4-5) group,moderate score (6-8) group and high score (9-11) group due to S.O.L.V.E.scoring system,and the stone-free rates were 93.5% (130/139),70.5% (153/217) and 37.5% (9/36),respectively (P <0.01).The operation time of low,moderate,andi high score group were (31.6 ± 10.9),(42.3 ± 18.3),and (58.0 ± 19.2) min,respectively.Additionally,the score was correlated with the operation time(P <0.01),but not with postoperative hospital stay (P =0.133),intraoperative bleeding (P =0.185) and postoperative infectious fever (P =0.839).In logistic regression model analysis,the stone surface area,length of calyces funnel,number of involved calyces were significantly correlated with SFR (P < 0.01).The obstruction degree and essence of stone were not associated with SFR (P > 0.05).The area under receiver operating characteristic curve of S.O.L.V.E.score was 0.782,higher than that of each variable in S.O.L.V.E.scoring system(S,O,L,V,E were 0.738,0.535,0.698,0.735,0.593,respectively).Conclusions The stone surface area,length of calyces funnel,number of involved calyces were significantly correlated with SFR.The S.O.L.V.E.nephrolithometry scoring system can predict SFR after FURS accurately,and provide assistance for making clinical decisions.