1.Effect of hemorheology on ultrasonic doppler blood flow spectrum diagram.
Journal of Biomedical Engineering 2014;31(4):798-800
The present research aims to point out the long-existing defect of analyzing the spectrum diagram only from the perspective of haemodynamics instead of haemorheology. In the light of the theories of haemodynamics and haemorheology, the causes of spectrum diagram formation of carotid artery blood at the rapid and slow flow can be clarified completely and accurately. Four conclusions have been drawn in the end. As long as the velocity gradient is large enough, obvious red blood cells concentrate to the shaft even in the big or bigger blood vessels; the spectrum diagram is the powerful proof of the two phase flow model of blood; the spectrum diagram can be completely and accurately analyzed only by combining haemodynamics with haemorheology; and only when the red blood cells concentrate to the shaft, the big or bigger blood vessels can be regarded as haemogeneous fluid.
Blood Flow Velocity
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Carotid Arteries
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diagnostic imaging
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Hemodynamics
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Hemorheology
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Humans
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Ultrasonography, Doppler
2.Summing up Experiences and Pushing the Development of Clinical Hemorheologic of my Nation in Depth
Chinese Journal of Medical Physics 2010;27(2):1821-1824
Objective: Pushing the development of scientific research, education and clinical applying of hemorheologic in eath part comprehensively and in depth. Methods: Summarizing the experiences, lessons and questions in scientific research, edu-cation and clinical applying of hemorheologic in twenty and more years, clarifying the harm of high viscosity to health. Re-sults: Stating the foundation, necessity and feasibility of the overall and deep development have been possessed. Conclusions: Hemorheologic can be developed comprehensively and in depth provided that studying good experiences, cultivating talent, playing the role of learning organizations and conquering the existing questions.
4.EFFECT OF LYCIUM BARBARUM POLYSACCHARIDE ON ANTITUMOR ACTIVITY AND IMMUNE FUNCTION
Lu GAN ; Shenghua ZHANG ;
Acta Nutrimenta Sinica 1956;0(02):-
Objective: To study the antitumor effect of Lycium barbarum polysaccharide (LBP X) and its immunity regulating effect on S 180 bearing mice. Methods: S 180 bearing mice were used as animal model. The effect of LBP X on tumor weight and immune function was observed. Results: LBP X could inhibit the growth of S 180 effectively and increase thymus index, the macrophage phagocytic function, anti SRBC antibody secreted by the spleen cells, lymphocyte proliferation and CTL activity and decrease LPO markedly in S 180 bearing mice. Conclusion: The mechanism of tumor inhibition by LBP X was due to enhance the immune function.
6.U-100 laser lithotripsy through extra-thin choledochoscope under mini-incision for refractory choledocholithiasis
Chenggang ZHANG ; Shenghua ZHANG ; Shouquan FENG
Chinese Journal of Current Advances in General Surgery 1999;0(03):-
Objective:To explore the value of applying the U-100 laser lithotripsy through extra-thin choledochoscope under miniincision to treat the refractory common bile duct stones.Methods:The curative effect and complications of 68 patients were observed.Results:All of the operations were succeeded whithout cases of death.67 cases’ biliary stones were completely removed,and the stone free rate is 98.52%,only 4 cases have complications.Transcystic bile duct exploration were performed in 29 patients,and CBDE were performed in 39 patients,the average postoperative time of in hospital stay is only 10.5 days.Conclusion:The treatment plan has the advantages of mini invasion,high efficiency and low postoperative complication rate,so it’s safe and practicable.
7.Relationship between ways of nutritional support and immune function in patients with malignant obstructive jaundice after PTCD
Shenghua YANG ; Chenghua ZHANG ; Linghong DU
Journal of Clinical Hepatology 2014;30(11):1148-1152
Objective To investigate the clinical effect of different nutritional therapies on the immune function of patients with malignant obstructive jaundice after percutaneous transhepatic cholangiodrainage (PTCD).Methods A total of 50 patients with malignant obstructive jaundice who were admitted to our hospital from January 2009 to March 2013 were randomly divided into two groups according to the admis-sion order.The patients in group A (n=25 )received enteral nutritional support after PTCD,and those in group B (n=25 )received total parenteral nutritional support after PTCD.Intra-group and inter-group comparisons were made in terms of jaundice clearance,nutritional indices,and body’s immune function on preoperative day 1 and postoperative day 7;comparison between the two groups was made by t test. Results Among the 50 patients who underwent PTCD,39 (78%)had good drainage,while 1 1 (22%)did not reach the expectation,of which,5 (10%)were in group A and 6 (12%)in group B.In both groups,the nutritional indices on postoperative day 7 were significantly higher than those on preoperative day 1(P<0.05),but no significant difference in these indices was observed between group A and group B on postoperative day 7 (P>0.05).The immune function of patients in both groups was significantly improved following PTCD and nutrition-al support (P<0.05),but there was no significant difference between the two groups (P>0.05).Although the same scheme of nutritional support was used,there were 1 1 patients who did not achieve the expected jaundice clearance after PTCD and had limited improvement in immune function compared with those who had complete jaundice clearance (all P<0.05).Conclusion Jaundice clearance is closely re-lated to PTCD in patients with malignant obstructive jaundice,but not markedly associated with the ways of nutritional support.
8.Experimental Study of the Neointimal of Balloon-injured Rabbit Carotid Arteries
Yi ZHANG ; Shushan QI ; Shenghua ZHOU
Journal of Chinese Physician 2001;0(02):-
Objective To observe the dynamic change of the intimal proliferation in balloon-injured rabbit carotid arteries to explore the mechanism of restenosis. Methods 40 healthy male New Zealand white rabbits were randomly divided into experiment groupsⅠ、Ⅱ、Ⅲ and control group, each group containing 10 rabbits. Right carotid artery was injured with PTCA balloon in the experiment groups. 10 rabbits in each experiment group were killed on 1, 2 and 4 weeks after injury. Morphological change of injured intimae was examined by light microscope and analyzed using a computerized imaging analysis system. Results In experiment group, neointimal areas were significantly more than those in control group(P
9.Protective Effect of Metformin on Kidney in Non-diabetic Hypertension Elderly
Yong ZHANG ; Shenghua ZHOU ; Guanghui FAN
Journal of Chinese Physician 2001;0(03):-
Objective To investigate the protection of metformin on kidney in non-diabetic hypertension elderly.Methods The patients was divided into two groups;one given nifedipine ,another given nifedipine plus metformin. Three months Later,the changes of body mass index (BMI), plasma insulin, urine protein, blood urea nitrogen(BUN), blood and urine ? 2-microglobulin(? 2-MG) were examined. Results Above-markers were reduced more remarkably in nifedipine plus metformin group than that in only nifedipine group(P
10.Expression of Vascular Endothelial Growth Factor in Patients With Acute Myocardial Infarction
Yi ZHANG ; Shushan QI ; Shenghua ZHOU
Journal of Chinese Physician 2001;0(03):-
Objective To investigate the clinical significance of vascular endothelial growth factor (VEGF) levels in the serum of patients with acute myocardial infarction (AMI),and also to explore the relationship between VEGF and creatine kinase (CK) levels in AMI.Methods 25 patients with AMI and 12 controls were used for this study. Serum was isolated from peripheral blood on day 1, 5, 10 and15 after the onset of AMI. VEGF levels were measured by enzyme-linked immunosorbant assay (ELISA).Results Serum VEGF levels elevated gradually after the onset of AMI and reached a peak on day 10, which was significantly higher than that of control group (178 9?48 9)pg/ml vs(64 9?16 7)pg/ml,P