1.Effects of Xuezhikang on carotid atherosclerosis plaque and blood lipids in patients with transient ischemic attack
Yingmin MO ; Min HAN ; Shengfang XIE
Journal of Clinical Neurology 1988;0(02):-
Objective To investigate the effects of Xuezhikang (XZK) on carotid atherosclerosis plaque and blood lipids in patients with transient ischemic attack (TIA). Methods 65 patients with TIA were randomly divided into two groups: XZK group and control group.XZK group received XZK and Aspirin for 6 months, while the control group received Aspirin only. The intima-midia thickness (IMT) of carotid artery,the area of carotid atherosclerosis plaque, and levels of blood lipids, oxidized low density lipoprotein cholesterol (ox-LDL) and serum nitric oxide (NO) were measured before and after treatment.Incidence rate of cerebrovascular event in the two groups were compared in 6 months. Results After 6 months of treatment, the total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and ox-LDL concentrations decreased significantly in XZK group, however high density lipoprotein (HDL) and NO levels increased markedly (all P0.05).Conclusion It is shown that XZK not only effectively adjusts blood lipids, inhibits peroxide of lipids and protects vascular endothelial, but also regresses the atherosclerosis and stabilizes the plaque.
2.Long-term clinical effects of Fogarty catheter on arteriovenous fistula thrombosis
Shengfang XIE ; Weiping GAO ; Liming FANG ; Yong HU ; Jianjing LIU ; Keling GAO
Chinese Journal of Geriatrics 2009;28(9):719-721
Objective To observe the long-term clinical effects of Fogarty catheter on arteriovenous fistula thrombosis and reperfusion rate in patients on hemodialysis. Methods The thrombosed vascular access was incised and F4 or F5 Fogarty catheter was inserted. After the Fogarty catheter passed through the thrombus, the heparin saline was infused into the balloon and then the catheter was pulled back. All the patients were followed up for 5-48 months. Results In 14 cases of total 15 patients embolisms were removed successfully and the blood flow during hemodialysis reached more than 200 ml/min. The catheter use time was (21.5±15.4) months in average and the longest use time was 48 months. Conclusions The recent and long-term effects of Fogarty catheter is good for arteriovenous fistula thrombosis, which prolongs the use period of autologous arteriovenous fistula and is worthy to be popularized.
3.Evaluate curative effect of chronic renal failure by methods of Bushen Jianpi Huoxue Paidu.
Shengfang XIE ; Yuanzhang YAO ; Jia ZHU
China Journal of Chinese Materia Medica 2009;34(16):2097-2100
OBJECTIVEThe evaluation of curative effect of CRF by Bushen Jianpi Huoxue Paidu and combination western medicine.
METHODGather articles mainly of VIP Information and Wanfang Data of the decade to cure CRF by Bushen Jianpi Huoxue Paidu and combination western medicine with random controlled way, and geostatistical analyse with RevMan4. 2 downloading from Cochrane Collaboration.
RESULTThe control group was 3.82 (95% CI, 2.72-5.38), in neurofunction 2 al impairment. The serum creatinine SMD = -0.72 (95% CI, -1.08-(-)0.35). Urea Nitrogen WMD = -3.32 (95% CI, -4.34-(-)2.29), P < 0.05.
CONCLUSIONIn addition to the routine treatment, the method of Bushen Jianpi Huoxue Paidu can be used by using some Chinese drugs to enhance the clinical effect.
Drugs, Chinese Herbal ; therapeutic use ; Humans ; Kidney ; drug effects ; physiopathology ; Kidney Failure, Chronic ; drug therapy ; physiopathology ; Randomized Controlled Trials as Topic
4.Analysis of influential factors of non-thyroidal illness syndrome in elderly inpatients
Shengfang CHEN ; Jiayin BI ; Haoming SONG ; Xinyi FEI ; Nanzi XIE
Chinese Journal of Geriatrics 2018;37(5):532-535
Objective To investigate the effects of risk factors on non thyroidal Illness syndrome (NTIS) in elderly inpatients.Methods A total of 819 elderly inpatients who met inclusion criteria were consecutively recruited in thiscross-sectional study.Physicalmeasurements and mini nutritional assessment using the mini nutritional assessment-short form (MNA-SF) score were conducted.A serum levels of thyroid stimulating hormone (TSH),free triiodothyronine (FT3),free thyroxine (FT4),brain natriuretic peptide (BNP) and C-reactive protein (CRP) were examined.Data were analyzed with multivariatelogistic regression.Results The significant differences were found between NTIS group (n=145) versus control group (n=674)inage (78.5±8.1) years vs.(75.1±8.6) years(t=5.422,P<0.01),in body mass index (23.0 ±3.8) kg/m2 vs.(24.1±3.6) kg/m2,in MNA-SF score 11.2±2.3 vs.12.3± 1.8(t=-3.315,6.754,P<0.01),in level of serum albumin (36.0±4.5) g/L vs.(38.4±3.6) g/L (t=-6.977,P<0.01),in triglyceride level (1.3± 0.9) mmol/L vs.(1.5±1.0) mmol/L(t=-3.039,P<0.01),inCRP (Z=-8.857,P<0.01)),and in BNP (t=6.331,P<0.01).Logistic regression analysis revealed that age> =80 years (OR=2.433,95%CI:1.357 4.361),malnutrition (OR=1.946,95%CI:1.261-3.001),renal insufficiency (eG FR<60 ml/min,OR =2.131,95% CI:1.367-3.322),and high level of CRP (10 mg/L and 50 mg/L:OR=3.446,95%CI:2.117-5.611;over 50 mg/L:OR =10.029,95%CI:4.693-21.432,all P<0.01)) were risk factors for NTIS.Conclusions Non-thyroidal illness syndrome in elderly inpatients is correlated with advanced age,renal insufficiency,malnutrition and stress,which are the independent risk factors.