200 units of eligible blood from donors with negative HBsAg reaction had been tested for hepatitis B virus markers (HBVM), using ELISA and dot-blot hybridization. The results of testing showed that 120 of the 200 units of blood had negative HBVM reaction, and the rest 80 units of blood had positive HBVM reaction. Among these 80 units of blood, 62 units had negative hepatitis B virus replication markers (HBVRM) and the rest 18 units had positive HBVRM. The rate, of post-transfusion HBV infection in the patients received HBVM (+) blood was 25.4%, significantly higher than the rate of post-transfusion HBV infection (3.75%) in the patients received HBVM (-) blood (P

Depression is the most common mental disorder in epilepsy, which means that they maybe have some common pathogene-sis. This paper discussed the biological relation mechanism, such as neurotransmitter, neuropeptide and its receptor, glial cell, immune-medi-ators, nerve signal transduction pathway, synaptic plasticity and nerve regeneration.

AIM: To investigate the effect of Ganoderma lucidum spores powder on the expression of insulin-like growth factor-1 (IGF-1), nuclear factor-?B (NF-?B) and apoptosis of nerve cells in rats with epilepsy established by pentetrazole. METHODS: The sub-eclampsia dosage of pentetrazole (PTZ) was used to make epilepsy model. Ganoderma lucidum spores powder group was given from stomach. The enduring time and latent period were recorded. The immune reactivity of IGF-1, NF-?B/P65 and apoptosis of nerve cells were measured with immunohistochemical staining and TUNEL method. RESULTS: In high power sight (?400), there were much more apoptosis cells in hippocampus and brain cortex of model group (18.80?2.13, 16.87?2.00) than those in control group (0.97?0.52, 0.58?0.25). The expressions of IGF-1, NF-?B in model group were higher than those in control group. Compared with model group, the latent period of Ganoderma lucidum spores powder group at the 17th, 21th, 25th days were longer (P

Objective: To introduce the SVF-gel as a filling, and the application of SVF-gel for the treatment of horizontal neck wrinkles. Methods: This investigation presented a retrospective study of 30 patients (age ranged from 25 to 56 years, with mean 36 years) in Guangzhou Eye-Nose-Fat Cosmetic Plastic Clinic from December 2017 to June 2019. We used the SVF-gel injection for horizontal neck wrinkles for the patients. The effectiveness was observed 1 to 6 months later. Results: No serious complications occurred in all patients. Postoperative evaluation of horizontal neck wrinkles showed that the swelling time lasted for 1-3 days, and the satisfactory rate of the doctors and patients after one month was 83.33% and 86.67%, and that after 6 months was 86.67 % and 83.33%, respectively. Conclusions SVF-gel is an effective treatment for horizontal neck wrinkles.

Objective:To investigate the relationship between parathyroid hormone（PTH） level and permanent hypoparathyroidism（PHPP） on the first day after radical papillary thyroidectomy, and its predictive value. Methods:A total of 80 patients with papillary thyroid cancer who underwent total thyroid resection and central lymph node dissection were collected and analyzed from January 2021 to January 2022. According to whether PHPP occurred after surgery, the patients were divided into hypoparathyroidism group and normal parathyroid function group, and univariate and binary logistics regression were used to analyze the correlation between PTH and serum calcium levels and PHPP on the first day after surgery in two groups. The dynamic changes of PTH at different time points after operation were analyzed. The area under the receiver operating characteristic was used to evaluate the predictive power of PTH on the development of PHPP after surgery. Results:Among the 80 patients with papillary thyroid cancer, 10 cases developed PHPP, with an incidence rate of 12.5%. Binary logistics regression analysis showed that PTH on the first postoperative day（OR=14.534, 95%CI: 2.377-88.858, P=0.004） was an independent predictive risk factor for postoperative PHPP. Taking PTH=8.75 ng/L on the first postoperative day as the cut-off value, the AUC of the area under the curve was 0.874（95%CI: 0.790-0.958, P<0.001）, the sensitivity was 71.4%, the specificity was 100%, and the Yoden index was 0.714. Conclusion:PTH level on the first day after total thyroid papillary carcinoma surgery is closely related to PHPP, and is an independent predictor of PHPP.
Humans ; Calcium ; Hypoparathyroidism/surgery* ; Parathyroid Glands ; Parathyroid Hormone ; Postoperative Complications/surgery* ; Thyroid Cancer, Papillary/surgery* ; Thyroid Neoplasms/complications* ; Thyroidectomy