1.Reform of teaching contents and curriculum system for medical staff's post-education in rural areas
Chinese Journal of Medical Education Research 2006;0(09):-
The current paper, pivoting on an analytical survey of the teaching contents and curriculum system of post-education for rural medical personnel, pinpoints the problems existing therein, and explores the various approaches for reforming the teaching contents and curriculum system.
3.Progress in genetic studies on severe cutaneous adverse reactions to anti-epileptic drugs.
Chinese Journal of Pediatrics 2012;50(12):906-908
Anticonvulsants
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adverse effects
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Asian Continental Ancestry Group
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genetics
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Carbamazepine
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adverse effects
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China
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epidemiology
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Drug Eruptions
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epidemiology
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ethnology
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genetics
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Genetic Predisposition to Disease
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genetics
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HLA-B Antigens
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genetics
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HLA-B15 Antigen
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genetics
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Humans
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Risk Factors
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Severity of Illness Index
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Skin
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pathology
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Stevens-Johnson Syndrome
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epidemiology
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etiology
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genetics
4.Seventy-eight cases of humeral epicondylitis treated by pricking and cupping combined with moxibustion.
Guo-Li NING ; Sheng-Yang HE ; Xing-Li LIU
Chinese Acupuncture & Moxibustion 2014;34(1):20-20
Acupuncture Therapy
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Adult
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Aged
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Combined Modality Therapy
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Female
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Humans
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Male
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Middle Aged
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Moxibustion
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Punctures
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Tennis Elbow
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therapy
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Treatment Outcome
6.Establishment of the mathematic model of total quantum statistical moment standard similarity for application to medical theoretical research.
Fuyuan HE ; Kaiwen DENG ; Sheng HUANG ; Wenlong LIU ; Jilian SHI
Acta Pharmaceutica Sinica 2013;48(9):1453-8
The paper aims to elucidate and establish a new mathematic model: the total quantum statistical moment standard similarity (TQSMSS) on the base of the original total quantum statistical moment model and to illustrate the application of the model to medical theoretical research. The model was established combined with the statistical moment principle and the normal distribution probability density function properties, then validated and illustrated by the pharmacokinetics of three ingredients in Buyanghuanwu decoction and of three data analytical method for them, and by analysis of chromatographic fingerprint for various extracts with different solubility parameter solvents dissolving the Buyanghanwu-decoction extract. The established model consists of four mainly parameters: (1) total quantum statistical moment similarity as ST, an overlapped area by two normal distribution probability density curves in conversion of the two TQSM parameters; (2) total variability as DT, a confidence limit of standard normal accumulation probability which is equal to the absolute difference value between the two normal accumulation probabilities within integration of their curve nodical; (3) total variable probability as 1-Ss, standard normal distribution probability within interval of D(T); (4) total variable probability (1-beta)alpha and (5) stable confident probability beta(1-alpha): the correct probability to make positive and negative conclusions under confident coefficient alpha. With the model, we had analyzed the TQSMS similarities of pharmacokinetics of three ingredients in Buyanghuanwu decoction and of three data analytical methods for them were at range of 0.3852-0.9875 that illuminated different pharmacokinetic behaviors of each other; and the TQSMS similarities (ST) of chromatographic fingerprint for various extracts with different solubility parameter solvents dissolving Buyanghuanwu-decoction-extract were at range of 0.6842-0.999 2 that showed different constituents with various solvent extracts. The TQSMSS can characterize the sample similarity, by which we can quantitate the correct probability with the test of power under to make positive and negative conclusions no matter the samples come from same population under confident coefficient a or not, by which we can realize an analysis at both macroscopic and microcosmic levels, as an important similar analytical method for medical theoretical research.
7.Value of interleukin-18 changes in early warning of organ dysfunction after trauma
Jingqu LIU ; Zhongjie HE ; Hongyuan LIN ; Yongming YAO ; Zhiyong SHENG
Chinese Journal of Trauma 2003;0(09):-
Objective To detect the changes of interleukin-18 (IL-18) in plasma of trauma patients and evaluate their value in early warning of organ dysfunction. Methods A prospective study was carried out in 54 trauma patients admitted in from March 2001 to September 2002, which were divided into low injury severity score(ISS) group (Group L-ISS) and high ISS group (Group H-ISS). ELISA was applied to measure the level of IL-18 of blood samples that were collected on arrival, at days 4, 7 and 14 following admission. In the meantime, IL-18 level of plasma samples from patients with systemic inflammatory response syndrome (SIRS), sepsis and multiorgan dysfunction syndrome (MODS) was retrospectively analyzed so as to calculate the critical value of IL-18 in predicting organ dysfunction. Results After trauma, IL-18 concentration of plasma reached peak at days 4 and 7, and decreased gradually at day 14, which was significantly related to SIRS, sepsis and MODS, respectively. The IL-18 level was high relatively in plasma from patients with organ dysfunction. The higher IL-18 level in plasma within seven days after trauma indicated the severer organ dysfunction. Conclusion IL-18 is sensitive in early warning of organ dysfunction after trauma.
8.Rheumatic diseases associated with myelodysplastic syndromes:nine cases report
Sheng-Tao ZHANG ; Pei-Gen HE ; Wen-Li LIU ;
Chinese Journal of Rheumatology 2003;0(07):-
Objective To investigate rheumatic disease manifestations in patients with myelodysplastic syndromes and explore possible causes.Methods Nine myelodysplastic syndromes(MDS)inpatients with rheumatic disease manifestations were reviewed retrospectively.Results Nine patients with the diagnosis of MDS had active rheumatic disease manifestations with various degree of hypergammaglobulinemia and positive autoantibodies.Two patients had rheumatoid arthritis(RA)and RA+anti-phospholipid syndrome(APS),four systemic lupus erythematosus(SLE)and SLE+polymyositis(PM),one patients had adult onset Still's disease, one with acute arthritis and cutaneous vassulitis,one had lupus-like manifestations including polyserositis,al- buminuria,hypocomplementemia and positive Commb's test.Conclusion The rheumatic disease manifesta- tions in patients with myelodysplastic syndromes are characterized by various active rheumatic disease manifes- tation.Immunological abnormalities and ineffective hematopoiesis are persistent.Immunologic abnormalities in MDS such as impaired function of T and B cells,hypergammaglobulinemia,positive autoantibodies,may be the causes of various rheumatic manifestations.We suggest that there is a significant association between myeludys- plastic syndrome and rheumatic diseases.
9.Study on antithrombogenicity and surface heparinization of small intestinal submucosa
Ben-Song HAN ; Cun-Yi FAN ; Sheng-He LIU ;
Chinese Journal of Orthopaedic Trauma 2004;0(10):-
Objective To study surface heparinization of small intestinal submucosa(SIS)and an- tithrombegenicity of beparinized SIS films with plasma initiation technique for the engineering vascular scaffolds. Methods The SIS films were grafted with heparin by hypothermia plasma initiation technique.The blood com- patibility of the modified SIS films was assessed by observing blood coagulation time in vitro and the long term pa- tency of hepafinized SIS vascular scaffolds directly under the circulation of blood.Results The hypothermia plasma initiation method could attach heparin onto the SIS surface,The water contact angle of SIS films modified with heparin was decreased while the surface free energy and hydrophilicity increased.The prothrombin time(PT),ac- tivated partial thromboplastin time(APTT)and thrombin clotting Time(TT)of the SIS films modified with heparin were prolonged obviously.Small caliber engineering vascular scaffold made of heparinized SIS films kept the patency for six weeks.Conclusion Heparin can be attached to SIS films by hypothermia plasma initiation technique.The modified surfaces provide good and persistent antithrombogenicity,and possess potent blood compatibility,
10.Therapy progress of spinal cord compression by metastatic spinal tumor.
Yao-sheng LIU ; Qi-zhen HE ; Shu-bin LIU ; Wei-gang JIANG ; Ming-xing LEI
China Journal of Orthopaedics and Traumatology 2016;29(1):94-98
Metastatic epidural compression of the spinal cord is a significant source of morbidity in patients with systemic cancer. With improvment of oncotheray, survival period in the patients is improving and metastatic cord compression is en- countered increasingly often. Surgical management performed for early circumferential decompression for the spinal cord com- pression with spine instability, and spine reconstruction performed. Patients with radiosensitive tumours without spine instabili- ty, radiotherapy is an effective therapy. Spinal stereotactic radiosurgery and minimally invasive techniques, such as vertebro- plasty and kyphoplasty, percutaneous pedicle screw fixation, radiofrequency ablation are promising options for treatment of cer- tain selected patients with spinal metastases.
Decompression, Surgical
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Humans
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Minimally Invasive Surgical Procedures
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Spinal Cord Compression
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therapy
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Spinal Neoplasms
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secondary
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therapy