Humans ; Vitamin D ; poisoning ; Vitamins ; poisoning

Object To determine the histochemical location d eposited artemisinin and to provide selection character for screening of Artemisia annua L. which contains rich content of artemisinin Methods Artemisinin was located by the histochemic al method and then statistical method was used to ascertain the correlation betw een the content of artemisinin and the density of biseriate glandular triche mes (BGT) Results Artemisinin is located in both BGT and non glandular T -shaped filamentous trichomes (NTFT) in A annua leave s The content of artemisinin had a positive correlation with the density of BG T in A annua leaves Conclusion High density of BGT in foliar tissue might be considered as one of the selection characters for the screening of A. annua with rich content of artemisinin

Objective To observe the effects ofTanyu Tongzhi Formula on proliferation and migration of human umbilical vein endothelial cells (HUVECs);To explore its activity of pro-angiogenesis.Methods HUVECs were cultured in vitro. Rats were treated with gavage containing different doses ofTanyu Tongzhi Formula (78.0, 39.0, 19.5 g/kg) to prepare serum with different doses of medicine. The activity of HUVECs was measured by MTT method. The effects on migration of HUVECs were inspected by using scratch wound assay.Results Compared with the normal control group, serum containing high-dose and medium-doseTanyu Tongzhi Formula could significantly promote the proliferation of the HUVECs (P<0.01). The rates were 49.78% and 33.92% respectively. And the cell migration rate was higher in the two groups than in the normal control group (P<0.01). The rates were 11.36% and 11.62% respectively.ConclusionTanyu Tongzhi Formula can promote proliferation and migration in HUVEC, which may be active to pro-angiogenesis.

In order to improve the effect of teaching and teachers' ability,make our teaching methods adapt to the social development,the department of Endocrinology used the method of preparing lessons collectively in our teaching.We found that the method not only made the the supply of teachers reasonably but also made good contribution to the students' culture.Practice testified that the method of preparing lessons collectively could adapt to the new model of cultivation and create substantial results.

BACKGROUND: At present, more and more scholars pay attention to the influence of spine and pelvis sagittal balance on the quality of life of patients. Postoperative changes in spine imaging parameters fol owing corrective osteotomy for lumbar degenerative kyphosis have not been reported. OBJECTIVE: To evaluate postoperative changes in sagittal balance fol owing corrective osteotomy for lumbar degenerative kyphosis. METHODS: We retrospectively analyzed 35 consecutive lumbar degenerative kyphosis patients treated with posterior osteotomy fixation in the First Affiliated Hospital of Xinjiang Medical University from February 2012 to December 2014. Imaging parameters were measured before fixation, immediately after fixation and during final fol ow-up. RESULTS AND CONCLUSION: (1) There were significant differences between preoperative and postoperative parameters except for pelvic incidence angle (P < 0.05). (2) There were significant differences between postoperative and last fol ow-up parameters except for Cobb angle, pelvic incidence angle, thoracic kyphosis angle and the thoracolumbar kyphosis (P < 0.05). (3) Pelvic tilt angle was negatively correlated with lumbar lordosis after fixation (r=-0.610, P < 0.001). Thoracic kyphosis was positively correlated with lumbar lordosis (r=0.598, P < 0.001). (4) Results suggested that lumbar sagittal contour can be significantly improved by corrective osteotomy for lumbar degenerative kyphosis. Simultaneously, reciprocal changes in the adjacent areas such as thoracic spine and pelvis occur to adapt to the new sagittal balance.

Objective To assess the efficiency ,safety and feasibility of percutaneous renal sympa-thetic denervation (RSD) for elderly refractory hypertension patients .Methods Office and ambu-latory blood pressures ,serum levels of creatinine ,angiotensin Ⅱ and aldosterone ,estimated glo-merular filtration rate (eGFR) and rennin activity were measured in 20 elderly refractory hyper-tension patients before and 1 ,3 ,6 months after percutaneous RSD .Complications of percutaneous RSD were observed .Results The office and ambulatory blood pressures were 16 .9/11 .9 mm Hg (1 mm Hg=0 .133 kPa) ,24 .8/17 .1 mm Hg ,29 .1/20 .5 mmHg and 24 .2/17 .2 mm Hg lower 1 , 3 ,6 months after percutaneous RSD than before percutaneous RSD ( P< 0 .01 ) .No significant difference was found in serum creatinine level and eGFR before and after percutaneous RSD (P>0 .05) .The creatinine ,angiotensin Ⅱand aldosterone levels were significantly lower after percuta-neous RSD than before percutaneous RSD (P<0 .05) .Femoral artery hematoma was detected in 1 patient .Conclusion Percutaneous RSD is a safe ,effective and feasible procedure for elderly re-fractory hypertension patients .

Zn. Conclusion Human activities developed along the Huaihe River does not influence the concentration of heavy metals in the sediment, no serious contamination of heavy metals in the sediment is found in the present investigation.

Objective To explore high risk factors of large instestine cancer in loudi city.Methods 132 cases of large intestine cancer of in-patients were reviewed from jan 1990 to Dec 2001,we used paired patients with non-alimentaly system disease as comparative studing group.Results By one way analysis (ANOVA method) of condition logistic regression showed that familial tumor,ulcerative colitis,intestinal polyp,schistosome infection,hormone substitution therapy etc diseases history,social-ecnomical situation,consumed fibre (fruits,vegetables),consumtions of friying meat treated with high temperature,salted fish and salted meat,frying food in oil,smoking≥35 years,physical training were all related to large intestine pathogenesis.Five risk factors were scrrened by condition logistics multiple factors,they were familial tumor histor,intake frying food in oil,smoking ≥35-age,number of calcium intake.Conclusion Large intestine pathogenesis in loudicyte were related to familiar tumor history,intake frying fook in oil,salted fish and salted meat consumption,smoking ≥35 years and number of calcium intake.

Aim To explore the effects of Baixiangdan capsule on learning and memory in PMS rat model with liver-qi invasion syndrome. Methods Liver-qi inva-sion rat model was prepared using foot-shock and noise stimulation, and then the model was treated with drugs, finally all the group of rats were evaluated using open-field test. We also detected learning and memory function of PMS liver-qi invasion rats model using Y-maze, new-object recognition and Morris water maze test. Results Compared with the normal group, the total distance increased significantly, number of crosses into the central area and duration of movement in the central area decreased significantly in model group. The total distance decreased significantly, number of crosses into the central area and duration of movement in the central area increased significantly in Baixiang-dan treatment group compared to the model group, and the total distance decreased significantly in fluoxetine treatment group compared to the model group. Com-pared with the normal group, DI decreased significant-ly in model group, and DI increased significantly in Baixiangdan treatment group. During place navigation training, the model group’ s escape latency was obvi-ously delayed on 2nd, 4th day. Compared with the model group, Baixiangdan and fluoxetine treatment group’ s escape latency was obviously reduced. During spatial probe test, compared with the normal group, the escape latency was obviously delayed, and the number of crossing platforms was significantly reduced in the model group. Compared with the model group, the number of crossing platforms significantly increased in Baixiangdan treatment group. Conclusion PMS liver-qi invasion rat model presents learning and memo-ry damage, which could be improved by Baixiangdan capsules, and the treatment effect may be superior to that of fluoxetine.

OBJECTIVE:To provide reference for rational drug use in the clinic. METHODS:The calculation was carried out in type,amount and consumption sum of Chinese patent medicines containing Salvia miltiorrhiza in our hospital during 2011-2014. These data were analyzed,classified and sorted by DDDs sequence and the method of pharma-coeconomics with Excel statistically. RESULTS:The consumption sum of Chinese patent medicines containing S. miltiorrhiza took on little changes in our hospital dur-ing 2011-2014,decreasing by 10.52% in 2012 compared to 2011 but increasing by 8.49% in 2013 compared to 2012. The order of DDDs kept stable,indicating that Chinese patent medicines containing S. miltiorrhiza were used frequently in 4 year. The order of consumption sum also kept stable relatively. CONCLUSIONS:The utilization of Chinese patent medicines containing S. miltiorrhi-za in our hospital is rational. Those with suitable prices and proved efficacy take a great share in the clinical application.