Biomedical Engineering ; Reconstructive Surgical Procedures ; Surgery, Plastic

Adult ; Asbestos ; adverse effects ; Humans ; Male ; Mesothelioma ; chemically induced ; Occupational Diseases ; chemically induced ; Pleural Neoplasms ; chemically induced

Breast cancer metastasis suppressor 1(BRMS1)can suppress the tumor cells metastasis. and significantly reduces the metastasis without affecting tumor growth. The relevant mechanism(s)may be related to intercellular communication, phosphoinositide signal transduction and interaction with NF-KB, and so on. Therefore, exploring the mechanisms of inhibition of tumor metastasis might be helpful for use of BRMS1 as tumor gene therapy.

Totally digitalized B-ultrasonography is the tendency of the development of ultrasonic medical instruments. Its basic technical characteristic is realizing real-time processing of the extremely huge ultrasonic data with digital electric circuit. This paper summarized the tendency of development and the primary techniques of signal processing, which including dynamic filtering, log amplification, envelope detection and secondary sampling. Furthermore, various techniques in different procedure of signal processing are introduced in detail.

Dentistry ; Educational Measurement ; Licensure, Dental ; Prosthodontics ; education

Objective:To establish hospital infection data sharing and service platform for collecting and issuing the hospital infection data. Methods:The relational database was used to realize data storage and J2EE light structure was employed to enhance the development and the operating efficiency and flexibility of the system according to the principles of Web information system.Results and Conclusion:An open and sharing hospital infection data platform for data processing, retrieving and analyzing was established. The established hospital infection data set and surgery infection data set contained more than 20 000 records. The system provided an effective software platform support for the utilization of hospital infection data and the prevention and control of hospital infection. This article introduces key technologies of the design and realization of the system.

Adult ; Biopsy ; methods ; Bronchoscopy ; Humans ; Lung ; pathology ; Male ; Middle Aged ; Pneumoconiosis ; diagnosis ; pathology

The paper described the building of a nursing team in a newly built hospital.The process consists of setting up the nursing department in advance and developing rules and regulations;enhancing nurse rotations and training to enhance their professionalism; building a seamless communication to make a supportive environment and sense of belongings; enhancing education of professional spirit to train the nurses to respect their career.All these provide the hospital with solid support of nursing team building.

Objective To investigate the expression and significance of Peripheral blood of Toll-like receptor-4 and cytotoxic T lymphocyte-associated antigen-4 in patients with essential hypertension. Methods We selected 35 patients with hypertension and 20 healthy people.We used flow cytometry to investigate TLR4 expression levels, and ELISA to detect the expression of CTLA-4. Results TLR4 expression in peripheral blood of patients with hypertension was (8.63 ±1.16)%, significantly higher (5.27 ± 1.25)%.The difference was statistically significant (t = 6.16,P < 0.05); CTLA-4 expression in peripheral blood of patients with hypertension was significantly higher (P<0.05); Hypertensive patients with CTLA-4 positive rate and TC, LDL-C was positively correlated (P<0.05); TLR4 and CTLA-4 was positive correlation (r = 0.886,P < 0.05). Conclusions TLR4 and CTLA-4 were high expression in hypertensive patients with hypertension,and related to hypertension.

Objective To investigate the effects of passaging on the proliferation,differentiation and apoptosis of neural stem cells.Methods Neural stem cells both from prime culture(P0) and twice-passaged culture(P2) were tested by enzyme immunoassay for proliferation and fluorescent activated cell sorting for apoptosis by Annexin V-FITC and propidium iodide.After being enduced to differentiation for 7 days,they were detected by the neuronal marker MAP2 and the astrocyte marker GFAP with nuclei staining by Hoechst 33342 additionally.The ratios of MAP2+/Hoechst+ and GFAP+/Hoechst+ were calculated.Results The absorbance of NSCs from P0 and P2 is 1.1899?0.0485(n=13)and 0.3526?0.1053(n=11)(P=0.000).Analyses of apoptosis using cytoflurometry are 40.91%?12.74% for P0(n=8)and 24.31%?13.01% for P2(n=9,P=0.018).The ratios of MAP2+/Hoechst+ and GFAP+/Hoechst+ of NSCs from P0 were 58.81%?9.69%(n=10)和22.85%?4.36%(n=10) while the ones for P2 were 27.84%?5.70%(n=10)and 49.32%?6.95%(n=10,P=0.000).Conclusions By passaging the proliferation and apoptosis of NSCs decreases and they differentiate into less neurons and more astrocytes.